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公开(公告)号:US20120321591A1
公开(公告)日:2012-12-20
申请号:US13595250
申请日:2012-08-27
申请人: Venkata Ramana Doppalapudi , Jing-Yu Lai , Bin Liu , Dingguo Liu , Joel Desharnais , Abhijit Suresh Bhat , Yanwen Fu , Bryan Douglas Oates , Gang Chen , Curt William Bradshaw
发明人: Venkata Ramana Doppalapudi , Jing-Yu Lai , Bin Liu , Dingguo Liu , Joel Desharnais , Abhijit Suresh Bhat , Yanwen Fu , Bryan Douglas Oates , Gang Chen , Curt William Bradshaw
IPC分类号: A61K38/18 , A61P35/00 , A61P19/02 , A61P9/12 , A61P13/12 , A61K38/21 , A61P27/06 , A61K39/395 , A61K33/36 , A61K38/50 , A61K33/24 , A61P27/02 , A61P17/06
CPC分类号: A61K47/48215 , A61K47/48246 , A61K47/48415 , A61K47/48507 , A61K47/60 , A61K47/64 , A61K47/6811 , A61K47/6835 , C07K14/71
摘要: The present invention provides various uses of VEGF binding peptides, including methods to treat disorders associated with abnormal angiogenesis. In addition, the invention provides VEGF peptides conjugated to antibodies alone and in conjunction with other anti-angiogenic molecules
摘要翻译: 本发明提供VEGF结合肽的各种用途,包括治疗与异常血管生成相关的疾病的方法。 此外,本发明提供了与单独的抗体和其它抗血管生成分子结合的VEGF肽
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公开(公告)号:US08293714B2
公开(公告)日:2012-10-23
申请号:US12432528
申请日:2009-04-29
申请人: Venkata Ramana Doppalapudi , Jing-Yu Lai , Bin Liu , Dingguo Liu , Joel Desharnais , Abhijit Suresh Bhat , Yanwen Fu , Bryan Douglas Oates , Gang Chen , Curt William Bradshaw
发明人: Venkata Ramana Doppalapudi , Jing-Yu Lai , Bin Liu , Dingguo Liu , Joel Desharnais , Abhijit Suresh Bhat , Yanwen Fu , Bryan Douglas Oates , Gang Chen , Curt William Bradshaw
IPC分类号: A61K38/16
CPC分类号: A61K47/48215 , A61K47/48246 , A61K47/48415 , A61K47/48507 , A61K47/60 , A61K47/64 , A61K47/6811 , A61K47/6835 , C07K14/71
摘要: The present invention provides VEGF binding peptides. In addition, the invention provides VEGF peptides conjugated to antibodies alone and in conjunction with other anti-angiogenic molecules. Various uses of the peptides and compounds are provided, including methods to treat disorders associated with abnormal angiogenesis.
摘要翻译: 本发明提供VEGF结合肽。 此外,本发明提供了与单独的抗体和其它抗血管生成分子结合的VEGF肽。 提供肽和化合物的各种用途,包括治疗与异常血管发生相关的疾病的方法。
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公开(公告)号:US20100003267A1
公开(公告)日:2010-01-07
申请号:US12432528
申请日:2009-04-29
申请人: Venkata Ramana Doppalapudi , Jing-Yu Lai , Bin Liu , Dingguo Liu , Joel Desharnais , Abhijit Suresh Bhat , Yanwen Fu , Bryan Douglas Oates , Gang Chen , Curt William Bradshaw
发明人: Venkata Ramana Doppalapudi , Jing-Yu Lai , Bin Liu , Dingguo Liu , Joel Desharnais , Abhijit Suresh Bhat , Yanwen Fu , Bryan Douglas Oates , Gang Chen , Curt William Bradshaw
IPC分类号: A61K39/395 , C07K14/00 , C07K19/00
CPC分类号: A61K47/48215 , A61K47/48246 , A61K47/48415 , A61K47/48507 , A61K47/60 , A61K47/64 , A61K47/6811 , A61K47/6835 , C07K14/71
摘要: The present invention provides VEGF binding peptides. In addition, the invention provides VEGF peptides conjugated to antibodies alone and in conjunction with other anti-angiogenic molecules. Various uses of the peptides and compounds are provided, including methods to treat disorders associated with abnormal angiogenesis.
摘要翻译: 本发明提供VEGF结合肽。 此外,本发明提供了与单独的抗体和其它抗血管生成分子结合的VEGF肽。 提供肽和化合物的各种用途,包括治疗与异常血管发生相关的疾病的方法。
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公开(公告)号:US08937048B2
公开(公告)日:2015-01-20
申请号:US13595250
申请日:2012-08-27
申请人: Venkata Ramana Doppalapudi , Jing-Yu Lai , Bin Liu , Dingguo Liu , Joel Desharnais , Abhijit Suresh Bhat , Yanwen Fu , Bryan Douglas Oates , Gang Chen , Curt William Bradshaw
发明人: Venkata Ramana Doppalapudi , Jing-Yu Lai , Bin Liu , Dingguo Liu , Joel Desharnais , Abhijit Suresh Bhat , Yanwen Fu , Bryan Douglas Oates , Gang Chen , Curt William Bradshaw
IPC分类号: A61K38/10 , C07K14/00 , C07K14/515 , A61K47/48 , C07K14/71
CPC分类号: A61K47/48215 , A61K47/48246 , A61K47/48415 , A61K47/48507 , A61K47/60 , A61K47/64 , A61K47/6811 , A61K47/6835 , C07K14/71
摘要: The present invention provides various uses of VEGF binding peptides, including methods to treat disorders associated with abnormal angiogenesis. In addition, the invention provides VEGF peptides conjugated to antibodies alone and in conjunction with other anti-angiogenic molecules.
摘要翻译: 本发明提供VEGF结合肽的各种用途,包括治疗与异常血管发生相关的疾病的方法。 此外,本发明提供了与单独的抗体和其它抗血管生成分子结合的VEGF肽。
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