Device and method for separation, concentration, and/or purification of cells
    1.
    发明授权
    Device and method for separation, concentration, and/or purification of cells 有权
    细胞分离,浓缩和/或纯化的装置和方法

    公开(公告)号:US08399205B2

    公开(公告)日:2013-03-19

    申请号:US12622924

    申请日:2009-11-20

    IPC分类号: G01N33/53

    CPC分类号: C12M47/04

    摘要: The present invention relates to methods and apparatuses for cell separation. In particular, the invention relates to separation of a particular cell type from a mixture of different cell types based on the differential rolling property of the particular cell type on a substrate coated with molecules that exhibits adhesive property with the particular cell type. The molecules can be directly coated on the surface or coated on nanoparticles that are adhered to the surface. This technology is adaptable for use in implantable shunts and devices for cell trafficking or tumor neutralization.

    摘要翻译: 本发明涉及细胞分离的方法和装置。 特别地,本发明涉及基于特定细胞类型的不同滚动性在不同细胞类型的混合物中分离特定细胞类型,所述特异性细胞类型在涂覆有表现具有特定细胞类型的粘合性质的分子的基质上。 分子可以直接涂覆在表面上或涂覆在粘附到表面的纳米颗粒上。 该技术适用于可植入分流器和用于细胞运输或肿瘤中和的装置。

    Device And Method For Separation, Concentration, And/Or Purification Of Cells
    2.
    发明申请
    Device And Method For Separation, Concentration, And/Or Purification Of Cells 有权
    细胞的分离,浓缩和/或纯化的装置和方法

    公开(公告)号:US20100167372A1

    公开(公告)日:2010-07-01

    申请号:US12622924

    申请日:2009-11-20

    IPC分类号: C12N11/00 C12M1/00

    CPC分类号: C12M47/04

    摘要: The present invention relates to methods and apparatuses for cell separation. In particular, the invention relates to separation of a particular cell type from a mixture of different cell types based on the differential rolling property of the particular cell type on a substrate coated with molecules that exhibits adhesive property with the particular cell type. The molecules can be directly coated on the surface or coated on nanoparticles that are adhered to the surface. This technology is adaptable for use in implantable shunts and devices for cell trafficking or tumor neutralization.

    摘要翻译: 本发明涉及细胞分离的方法和装置。 特别地,本发明涉及基于特定细胞类型的不同滚动性在不同细胞类型的混合物中分离特定细胞类型,所述特异性细胞类型在涂覆有表现具有特定细胞类型的粘合性质的分子的基质上。 分子可以直接涂覆在表面上或涂覆在粘附到表面的纳米颗粒上。 该技术适用于可植入分流器和用于细胞运输或肿瘤中和的装置。