公开(公告)号：US20180111954A1

公开(公告)日：2018-04-26

申请号：US15562973

申请日：2016-03-28

Applicant: Steven M. SILVERMAN ,  Bryon Ladd SIMMONS ,  Zhuqing LIU ,  Jing LIAO ,  Artis KLAPARS ,  Kevin R. CAMPOS ,  Ana Ines BELLOMO PERAZA ,  MERCK SHARP & DOHME CORP.

Inventor： Steven M. Silverman ,  Bryon Ladd Simmons ,  Zhuqing Liu ,  Jing Liao ,  Artis Klapars ,  Kevin R. Campos ,  Ana Inés Bellomo Peraza

IPC: C07H1/02 ,  C07H19/10 ,  C07H19/20 ,  C07F9/6558 ,  C07F9/58 ,  C07F9/24

CPC classification number: C07H1/02 ,  C07F9/242 ,  C07F9/58 ,  C07F9/65586 ,  C07H19/10 ,  C07H19/20

Abstract: The present invention is directed to process for making Compounds of Formula (II): (II), and salts thereof, wherein B, X, R2, R3, R4 R7, R8 and R9 are defined herein.