公开(公告)号：US06481515B1

公开(公告)日：2002-11-19

申请号：US09580083

申请日：2000-05-30

申请人： James F. Kirkpatrick ,  Harry B. Maddox ,  Kevin B. Clendenien ,  Andrew Weatherston ,  Charles W. Fisher ,  Gary G. Heaton ,  Larry R. Genskow ,  Christopher J. Binski

发明人： James F. Kirkpatrick ,  Harry B. Maddox ,  Kevin B. Clendenien ,  Andrew Weatherston ,  Charles W. Fisher ,  Gary G. Heaton ,  Larry R. Genskow ,  Christopher J. Binski

IPC分类号： B60K100

CPC分类号： A47L11/4011 ,  A47L11/03 ,  A47L11/10 ,  A47L11/12 ,  A47L11/24 ,  A47L11/29 ,  A47L11/292 ,  A47L11/4061 ,  A47L2201/00 ,  A47L2201/04

摘要： One aspect of the invention is directed to an autonomous mobile surface treating apparatus having a chassis, a drive mechanism mounted to the said chassis by a suspension, and a substantially rigid shell movably mounted to the chassis. The suspension includes a resilient member interposed between the drive mechanism and the chassis so that when the shell is pushed toward the supporting surface with a predetermined force the resilient member compresses to permit the drive mechanism to move and the shell and/or the chassis to contact the supporting surface. A second aspect of the invention is directed to the movable support of shell relative to the chassis. The shell is supported by a plurality of elongated elastic supports received within plurality of elongated openings in the chassis. Preferably, a passive portion of a collision detection sensor is attached to a central portion of the shell. A third aspect of the invention is directed to a non-skid lower edge member movably attached to the shell to adjust a clearance between the non-skid lower edge member and the supporting surface. A fourth aspect of the invention is directed to a vacant volume that defines a module receiving area adapted to removeably receive a surface treatment module, preferably a plurality of types of surface treatment modules including a pressure adjusting module. A fifth aspect of the invention is directed to a surface treatment module adapted to be removably received in a surface treatment module receiving area of an autonomous mobile surface treating apparatus.

摘要翻译： 本发明的一个方面涉及一种自主的移动表面处理装置，其具有底盘，通过悬架安装到所述底盘的驱动机构和可移动地安装到底架的基本上刚性的外壳。 悬架包括插入在驱动机构和底盘之间的弹性构件，使得当壳体以预定的力被推向支撑表面时，弹性构件被压缩以允许驱动机构移动并且壳体和/或底架接触 支撑面。 本发明的第二方面涉及壳体相对于底盘的可移动支撑件。 壳体由容纳在底盘中的多个细长开口内的多个细长弹性支撑件支撑。 优选地，碰撞检测传感器的被动部分附接到壳体的中心部分。 本发明的第三方面涉及一种可滑动地附接到壳体上的无滑动下边缘构件，以调节防滑下边缘构件与支撑表面之间的间隙。 本发明的第四方面涉及一种空容积，其限定适于可移除地接收表面处理模块的模块接收区域，优选多个类型的包括压力调节模块的表面处理模块。 本发明的第五方面涉及一种表面处理模块，其适于可拆卸地容纳在自动移动表面处理装置的表面处理模块接收区域中。

公开(公告)号：US5383496A

公开(公告)日：1995-01-24

申请号：US160956

申请日：1993-12-03

申请人： Donald Y. Bridges ,  Charles W. Fisher

发明人： Donald Y. Bridges ,  Charles W. Fisher

IPC分类号： F16L21/06 ,  F16L55/172 ,  F16L21/02

CPC分类号： F16L55/172 ,  F16L21/06 ,  Y10S285/91

摘要： A pipe coupling wherein the axial split is offset from the location wherein the coupling is closed. The offset increases the resistance of the pipe coupling to lifting forces exerted by pressurized fluid in pipes or pipelines. In addition, an extension member and a reinforcing member on the opposite sides of the closure device increase the section modulus of the pipe coupling and further increase the resistance of the pipe coupling to lifting forces.

摘要翻译： 一种管接头，其中所述轴向分离件偏离所述联接器关闭的位置。 偏移增加了管接头对加压流体在管道或管道中施加的提升力的阻力。 此外，在闭合装置的相对侧上的延伸构件和加强构件增加了管接头的截面模数，并进一步增加了管接头对提升力的阻力。

公开(公告)号：US20130212172A1

公开(公告)日：2013-08-15

申请号：US13370916

申请日：2012-02-10

申请人： Charles W. FISHER ,  Pace G. WILLISSON

发明人： Charles W. FISHER ,  Pace G. WILLISSON

IPC分类号： G06F15/16

CPC分类号： G06Q50/01

摘要： A method, computer program product, and computer system for providing, using a processor of a computer, at least a portion of text that includes a link for use by a website. A plurality of posts associated with an online social network is monitored using the processor of the computer to determine whether the link is present in at least one post of the plurality of posts. A first user of the online social network that has the link included in the at least one post is identified using the processor of the computer, where the at least one post of the first user identifies a second user of the online social network. Information associated with the first user is recorded in a data store using the processor of the computer in response to identifying that the first user has the link posted in the at least one post.

摘要翻译： 一种用于使用计算机的处理器提供至少一部分文本的方法，计算机程序产品和计算机系统，所述文本的至少一部分包括由网站使用的链接。 使用计算机的处理器监视与在线社交网络相关联的多个帖子，以确定链接是否存在于多个帖子的至少一个帖子中。 使用计算机的处理器识别具有包括在至少一个帖子中的链接的在线社交网络的第一用户，其中第一用户的至少一个帖子标识在线社交网络的第二用户。 响应于识别出第一用户具有在至少一个帖子中张贴的链接，与第一用户相关联的信息被记录在数据存储器中，使用计算机的处理器。

公开(公告)号：US5420027A

公开(公告)日：1995-05-30

申请号：US908317

申请日：1992-07-02

申请人： Charles W. Fisher ,  Henry J. Barnes ,  Ronald W. Estabrook

发明人： Charles W. Fisher ,  Henry J. Barnes ,  Ronald W. Estabrook

IPC分类号： C12N1/21 ,  C12N9/02 ,  C12N15/53 ,  C12N15/67 ,  C12N15/70 ,  C12N15/62 ,  C12N15/63

CPC分类号： C12N9/0077 ,  C12N15/67 ,  C12N15/70 ,  C12N9/0085 ,  C12Y114/99009 ,  C07K2319/00

摘要： Disclosed are methods and compositions for effecting bacterial expression of eukaryotic cytochrome P450 enzymes and fusion proteins comprising a eukaryotic P450 domain fused to a reductase enzyme domain in a biologically active form. Certain embodiments involve the expression of eukaryotic cytochrome P450.sub.17.alpha. -hydroxylase which is expressed in large amounts in an E. coli host in a biologically active form without the need for coexpression or admixture of a cytochrome P450 reductase. Methods and compositions are also disclosed for the construction of cytochrome P450 enzyme hybrids or fusion proteins, incorporating the N-terminal 9 amino acids from bovine 17.alpha.-hydroxylase, which will enable many eukaryotic cytochrome P450 enzymes or fusion proteins to be expressed in bacteria.

摘要翻译： 公开了用于实现真核细胞色素P450酶和融合蛋白的细菌表达的方法和组合物，其包含与生物活性形式的还原酶结构域融合的真核P450结构域。 某些实施方案涉及在生物活性形式的大肠杆菌宿主中大量表达的真核细胞色素P45017α-羟化酶的表达，而不需要共表达或混合细胞色素P450还原酶。 还公开了用于构建细胞色素P450酶杂交体或融合蛋白的方法和组合物，其结合来自牛17α-羟化酶的N-末端9个氨基酸，这将使许多真核细胞色素P450酶或融合蛋白在细菌中表达。

公开(公告)号：US09171337B2

公开(公告)日：2015-10-27

申请号：US13370916

申请日：2012-02-10

申请人： Charles W. Fisher ,  Pace G. Willisson

发明人： Charles W. Fisher ,  Pace G. Willisson

IPC分类号： G06F15/16 ,  G06Q50/00

CPC分类号： G06Q50/01

摘要： A method, computer program product, and computer system for providing, using a processor of a computer, at least a portion of text that includes a link for use by a website. A plurality of posts associated with an online social network is monitored using the processor of the computer to determine whether the link is present in at least one post of the plurality of posts. A first user of the online social network that has the link included in the at least one post is identified using the processor of the computer, where the at least one post of the first user identifies a second user of the online social network. Information associated with the first user is recorded in a data store using the processor of the computer in response to identifying that the first user has the link posted in the at least one post.

摘要翻译： 一种用于使用计算机的处理器提供至少一部分文本的方法，计算机程序产品和计算机系统，所述文本的至少一部分包括由网站使用的链接。 使用计算机的处理器监视与在线社交网络相关联的多个帖子，以确定链接是否存在于多个帖子的至少一个帖子中。 使用计算机的处理器识别具有包括在至少一个帖子中的链接的在线社交网络的第一用户，其中第一用户的至少一个帖子标识在线社交网络的第二用户。 响应于识别出第一用户具有在至少一个帖子中张贴的链接，与第一用户相关联的信息被记录在数据存储器中，使用计算机的处理器。

公开(公告)号：US1791189A

公开(公告)日：1931-02-03

申请号：US46146830

申请日：1930-06-16

申请人： CHARLES W FISHER

发明人： BURTON CHARLES H

IPC分类号： B65G51/30

CPC分类号： B65G51/30