公开(公告)号：US20090041736A1

公开(公告)日：2009-02-12

申请号：US12281448

申请日：2007-03-07

申请人： Norbert Sprenger ,  Francois Morgan ,  Rafael Berrocal ,  Marcel Braun ,  Chistine Cherbut ,  Peter Duncan

发明人： Norbert Sprenger ,  Francois Morgan ,  Rafael Berrocal ,  Marcel Braun ,  Chistine Cherbut ,  Peter Duncan

IPC分类号： A61K35/74 ,  A61P31/04 ,  A23L1/30

CPC分类号： A61K35/747 ,  A23C9/1425 ,  A23L33/10 ,  A23L33/135 ,  A23L33/26 ,  A23L33/40 ,  A23V2002/00 ,  A23Y2220/63 ,  A23Y2220/71 ,  A23Y2220/73 ,  A23Y2300/29 ,  A23Y2300/49 ,  A23Y2300/55 ,  A61K35/745 ,  A61K47/26 ,  A23V2250/28 ,  A23V2250/5438

摘要： This invention relates to a preparation comprising a probiotic bacterial strain and a prebiotic mixture comprising 5-70 wt % of at least one N-acetylated oligosaccharide selected from the group comprising Ga1NAcα1,3Ga1β1,4G1c and Ga1β1,6Ga1NAcα1,3Ga1β1,4G1c, 20-95 wt % of at least one neutral oligosaccharide selected from the group comprising Ga1β1,6Ga1, Ga1β1,6Ga1β1,4G1c Ga1β1,6Ga1β1,6G1c, Ga1β1,3Ga1β1,3G1c, Ga1β1,3Ga1β1,4G1c, Ga1β 1,6Ga1β 1,6Ga1β 1,4G1c, Ga1β 1,6Ga1β 1,3Ga1β 1,4GIc Ga1β 1,3Ga1β 1,6Ga1β 1,4GIc and Ga1β1,3Ga1β1,3Ga1β1,4G1c and 2-50 wt % of at least one sialylated oligosaccharide selected from the group comprising NeuAcα2,3Ga1β1,4G1c and NeuAcα2,6Ga1β1,4G1c. The invention extends to food products comprising said preparation and to the use of the preparation in the prevention and treatment of infections.

摘要翻译： 本发明涉及包含益生菌菌株和益生元混合物的制剂，其包含5-70重量％的至少一种N-乙酰化寡糖，其选自包含Ga1NAcalpha1,3Ga1beta1,4G1c和Ga1beta1,6Ga1NAcalpha1,3Ga1beta1,4G1c，20- 95重量％的选自包含Ga1beta1,6Ga1，Ga1beta1,6Ga1beta1,4G1c Ga1beta1,6Ga1beta1,6G1c，Ga1beta1,3Ga1beta1,3G1c，Ga1beta1,3Ga1beta1,4G1c，Ga1beta1,3Ga1beta1,4G1c，Ga1beta1,6Ga1beta1,4G1b，Ga1beta1,6Ga1beta1,4G1b， 4G1c，Ga1beta1,6Ga1beta1,3Ga1beta1,4GiCGa1beta1,3Ga1beta1,6Ga1beta1,4GIc和Ga1beta1,3Ga1beta1,3Ga1beta1,4G1c以及2-50wt％选自NeuAcalpha2,3Ga1beta1的至少一种唾液酸化寡糖 ，4G1c和NeuAcalpha2,6Ga1beta1,4G1c。 本发明延伸到包含所述制剂的食品和用于预防和治疗感染的制剂中。