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公开(公告)号:US20090041736A1
公开(公告)日:2009-02-12
申请号:US12281448
申请日:2007-03-07
申请人: Norbert Sprenger , Francois Morgan , Rafael Berrocal , Marcel Braun , Chistine Cherbut , Peter Duncan
发明人: Norbert Sprenger , Francois Morgan , Rafael Berrocal , Marcel Braun , Chistine Cherbut , Peter Duncan
CPC分类号: A61K35/747 , A23C9/1425 , A23L33/10 , A23L33/135 , A23L33/26 , A23L33/40 , A23V2002/00 , A23Y2220/63 , A23Y2220/71 , A23Y2220/73 , A23Y2300/29 , A23Y2300/49 , A23Y2300/55 , A61K35/745 , A61K47/26 , A23V2250/28 , A23V2250/5438
摘要: This invention relates to a preparation comprising a probiotic bacterial strain and a prebiotic mixture comprising 5-70 wt % of at least one N-acetylated oligosaccharide selected from the group comprising Ga1NAcα1,3Ga1β1,4G1c and Ga1β1,6Ga1NAcα1,3Ga1β1,4G1c, 20-95 wt % of at least one neutral oligosaccharide selected from the group comprising Ga1β1,6Ga1, Ga1β1,6Ga1β1,4G1c Ga1β1,6Ga1β1,6G1c, Ga1β1,3Ga1β1,3G1c, Ga1β1,3Ga1β1,4G1c, Ga1β 1,6Ga1β 1,6Ga1β 1,4G1c, Ga1β 1,6Ga1β 1,3Ga1β 1,4GIc Ga1β 1,3Ga1β 1,6Ga1β 1,4GIc and Ga1β1,3Ga1β1,3Ga1β1,4G1c and 2-50 wt % of at least one sialylated oligosaccharide selected from the group comprising NeuAcα2,3Ga1β1,4G1c and NeuAcα2,6Ga1β1,4G1c. The invention extends to food products comprising said preparation and to the use of the preparation in the prevention and treatment of infections.
摘要翻译: 本发明涉及包含益生菌菌株和益生元混合物的制剂,其包含5-70重量%的至少一种N-乙酰化寡糖,其选自包含Ga1NAcalpha1,3Ga1beta1,4G1c和Ga1beta1,6Ga1NAcalpha1,3Ga1beta1,4G1c,20- 95重量%的选自包含Ga1beta1,6Ga1,Ga1beta1,6Ga1beta1,4G1c Ga1beta1,6Ga1beta1,6G1c,Ga1beta1,3Ga1beta1,3G1c,Ga1beta1,3Ga1beta1,4G1c,Ga1beta1,3Ga1beta1,4G1c,Ga1beta1,6Ga1beta1,4G1b,Ga1beta1,6Ga1beta1,4G1b, 4G1c,Ga1beta1,6Ga1beta1,3Ga1beta1,4GiCGa1beta1,3Ga1beta1,6Ga1beta1,4GIc和Ga1beta1,3Ga1beta1,3Ga1beta1,4G1c以及2-50wt%选自NeuAcalpha2,3Ga1beta1的至少一种唾液酸化寡糖 ,4G1c和NeuAcalpha2,6Ga1beta1,4G1c。 本发明延伸到包含所述制剂的食品和用于预防和治疗感染的制剂中。
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公开(公告)号:US09005682B2
公开(公告)日:2015-04-14
申请号:US12281448
申请日:2007-03-07
申请人: Norbert Sprenger , Francois Morgan , Rafael Berrocal , Marcel Braun , Christine Cherbut , Peter Duncan
发明人: Norbert Sprenger , Francois Morgan , Rafael Berrocal , Marcel Braun , Christine Cherbut , Peter Duncan
IPC分类号: A23L1/308 , A23L1/0528 , A23C9/123 , A01N63/02 , A23C9/142 , A23L1/29 , A23L1/30 , A61K47/26 , A01N63/00
CPC分类号: A61K35/747 , A23C9/1425 , A23L33/10 , A23L33/135 , A23L33/26 , A23L33/40 , A23V2002/00 , A23Y2220/63 , A23Y2220/71 , A23Y2220/73 , A23Y2300/29 , A23Y2300/49 , A23Y2300/55 , A61K35/745 , A61K47/26 , A23V2250/28 , A23V2250/5438
摘要: This invention relates to a preparation comprising a probiotic bacterial strain and a prebiotic mixture comprising 5-70 wt % of at least one N-acetylated oligosaccharide selected from the group comprising Ga1NAcα1,3Ga1β1,4G1c and Ga1β1,6Ga1NAcα1,3Ga1β1,4G1c, 20-95 wt % of at least one neutral oligosaccharide selected from the group comprising Ga1β1,6Ga1, Ga1β1,6Ga1β1,4G1c Ga1β1,6Ga1β1,6G1c, Ga1β1,3Ga1β1,3G1c, Ga1β1,3Ga1β1,4G1c, Ga1β 1,6Ga1β 1,6Ga1β 1,4GIc, Ga1β 1,6Ga1β 1,3Ga1β 1,4GIc Ga1β 1,3Ga1β 1,6Ga1β 1,4GIc and Ga1β1,3Ga1β1,3Ga1β1,4G1c and 2-50 wt % of at least one sialylated oligosaccharide selected from the group comprising NeuAcα2,3Ga1β1,4G1c and NeuAcα2,6Ga1β1,4G1c. The invention extends to food products comprising said preparation and to the use of the preparation in the prevention and treatment of infections.
摘要翻译: 本发明涉及包含益生菌菌株和益生元混合物的制剂,所述益生菌混合物包含5-70重量%的至少一种选自包含Ga1NAcα1,3Ga1和bgr; 1,4G1c和Ga1&bgr;1,6Ga1NAcα1,3Ga1和bgr的组合物的至少一种N-乙酰化寡糖。 1,4G1c,20-95重量%的至少一种选自包含Ga1&bgr; 1,6Ga1,Ga1&bgr; 1,6Ga1&bgr; 1,4G1cGa1&bgr; 1,6Ga1&bgr; 1,6G1c,Ga1&bgr; 1,3Ga1&bgr的中性寡糖 ; 1,3G1c,Ga1&bgr; 1,3Ga1&bgr; 1,4G1c,Ga1&bgr; 1,6Ga1&bgr 1,6Ga1&bgr 1,4GIc,Ga1&bgr; 1,6Ga1&bgr 1,3Ga1&bgr 1,4GIc Ga1&bgr; 1,3Ga1&bgr 1,6Ga1&bgr 1,4GIc和Ga1&bgr; 1,3Ga1&bgr; 1,3Ga1&bgr; 1,4G1c和2-50wt%选自NeuAcα2,3Ga1&bgr; 1,4G1c和NeuAcα2,6Ga1&bgr; 1,4G1c的至少一种唾液酸化寡糖。 本发明延伸到包含所述制剂的食品和用于预防和治疗感染的制剂中。
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公开(公告)号:US20090092729A1
公开(公告)日:2009-04-09
申请号:US12278918
申请日:2007-02-09
CPC分类号: A23L33/10 , A23L5/00 , A23L7/00 , A23L29/30 , A23L33/40 , A23V2002/00 , A61K31/702 , A23V2250/28 , A23V2250/704 , A23V2250/70 , A23V2250/156
摘要: An oligosaccharide mixture comprising 5-70 wt% of at least one N-acetylated oligosaccharide selected from the group comprising GalN Acα1,3Galβ1,4Glc and Galβ1,6GalN Acα1,3Gal⊕1,4Glc, 20-90 wt % of at least one neutral oligosaccharide selected from the group comprising Galβ1,6Gal, Galβ1,6Glβ1,4Glc Galβ1,6Galβ1,6Glc, Galβ1,Galβ1,3Glc, Galβ1,3Galβ1,4Glc, Galβ1,6Galβ1,6Galβ1,4Glc, Galβ1,6Galβ1,3Galβ1,4Glc, Galβ1,3Galβ1,6Galβ1,4Glc and Galβ1,3Galβ1,3Galβ1,4Glc and 5-50 wt % of at least one sialylated oligosaccharide selected from the group comprising NeuAcα2,3Galβ1,4Glc and NeuAcα2,6Gaβ1,4Glc; food products comprising said oligosaccharide mixture.
摘要翻译: 一种寡糖混合物,其包含5-70重量%的至少一种N-乙酰化寡糖,其选自GalN Acalpha1,3Galbeta1,4Glc和Galbeta1,6GalNAcalpha1,3Gal⊕1,4Glc,20-90wt%的至少一种中性 寡糖选自Galbeta1,6Gal,Galbeta1,6Glb1,4Glc Galbeta1,6Galbeta1,6Glc,Galbeta1,Galbeta1,3Glc,Galbeta1,3Galbeta1,4Glc,Galbeta1,6Galbeta1,6Galbeta1,4Glc,Galbeta1,6Galbeta1,3Galbeta1,4Glc,Galbeta1 ,3Galbeta1,6Galbeta1,4Glc和Galbeta1,3Galbeta1,3Galbeta1,4Glc以及5-50wt%选自NeuAcalpha2,3Galbeta1,4Glc和NeuAcalpha2,6Gabeta1,4Glc的至少一种唾液酸化寡糖; 包含所述寡糖混合物的食品。
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公开(公告)号:US20090035813A1
公开(公告)日:2009-02-05
申请号:US11816516
申请日:2006-02-21
IPC分类号: C12P21/06
CPC分类号: A23C9/14 , A23C9/1206 , A23L5/00 , A23L7/00 , A23L29/30 , A23L31/00 , A23L33/125 , A23L33/40 , A23V2002/00 , A23V2250/28 , A23V2200/304
摘要: An oligosaccharide mixture derived from animal milk, food products comprising said oligosaccharide mixture and a process for producing said oligosaccharide mixture.
摘要翻译: 来源于动物乳的寡糖混合物,包含所述寡糖混合物的食品和制备所述寡糖混合物的方法。
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公开(公告)号:US08361530B2
公开(公告)日:2013-01-29
申请号:US12278918
申请日:2007-02-09
IPC分类号: A23C9/00
CPC分类号: A23L33/10 , A23L5/00 , A23L7/00 , A23L29/30 , A23L33/40 , A23V2002/00 , A61K31/702 , A23V2250/28 , A23V2250/704 , A23V2250/70 , A23V2250/156
摘要: An oligosaccharide mixture comprising 5-70 wt % of at least one N-acetylated oligosaccharide selected from the group comprising GalN Acα1,3Galβ1,4Glc and Galβ1,6GalN Acα1,3Galβ1,4Glc, 20-90 wt % of at least one neutral oligosaccharide selected from the group comprising Galβ1,6Gal, Galβ1,6Glβ1,4Glc Galβ1,6Galβ1,6Glc, Galβ1,Galβ1,3Glc, Galβ1,3Galβ1,4Glc, Galβ1,6Galβ1,6Galβ1,4Glc, Galβ1,6Galβ1,3Galβ1,4Glc, Galβ1,3Galβ1,6Galβ1,4Glc and Galβ1,3Galβ1,3Galβ1,4Glc and 5-50 wt % of at least one sialylated oligosaccharide selected from the group comprising NeuAcα2,3Galβ1,4Glc and NeuAcα2,6Galβ1,4Glc; food products comprising said oligosaccharide mixture.
摘要翻译: 一种寡糖混合物,其包含5-70重量%的至少一种N-乙酰化寡糖,其选自GalNAcα1,3Gal& 1,4Glc和Gal&bgr; 1,6GalNAcα1,3Gal&bgr; 1,4Glc,20-90wt% 至少一种选自Gal和bgr; 1,6Gal,Gal&bgr; 1,6Gl和bgr; 1,4Glc Gal&bgr; 1,6Gal&bgr; 1,6Glc,Gal&bgr; 1,Gal&bgr; 1,3Glc,Gal&bgr; 1,3Gal&bgr ; 1,4Glc,Gal&bgr; 1,6Gal&bgr; 1,6Gal&bgr; 1,4Glc,Gal&bgr; 1,6Gal&bgr; 1,3Gal&bgr; 1,4Glc,Gal&bgr; 1,3Gal&bgr; 1,6Gal&bgr; 1,4Glc和Gal&bgr; 1 ,3Gal& 1,3gal&bgr; 1,4Glc和5-50wt%的选自NeuAcα2,3Gal&bgr; 1,4Glc和NeuAcα2,6Gal&bgr; 1,4Glc的至少一种唾液酸化寡糖; 包含所述寡糖混合物的食品。
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公开(公告)号:US08591981B2
公开(公告)日:2013-11-26
申请号:US11816516
申请日:2006-02-21
IPC分类号: A23C9/00
CPC分类号: A23C9/14 , A23C9/1206 , A23L5/00 , A23L7/00 , A23L29/30 , A23L31/00 , A23L33/125 , A23L33/40 , A23V2002/00 , A23V2250/28 , A23V2200/304
摘要: An oligosaccharide mixture derived from animal milk, food products comprising said oligosaccharide mixture and a process for producing said oligosaccharide mixture.
摘要翻译: 来源于动物乳的寡糖混合物,包含所述寡糖混合物的食品和制备所述寡糖混合物的方法。
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公开(公告)号:US08771780B2
公开(公告)日:2014-07-08
申请号:US13203867
申请日:2009-03-04
IPC分类号: A23C9/00
CPC分类号: C07H3/04 , A23L33/10 , A23L33/40 , A23V2002/00 , C07H3/06 , A23V2250/28 , A23V2250/70 , A23V2250/156 , A23V2200/322
摘要: An oligosaccharide ingredient comprising glycosylated amino acids and peptides of the general formula RnSacm where R is an amino acid residue, Sac is a monosaccharide selected from the group comprising N-acetyl-neuraminic acid, N-acetyl galactosamine and galactose, n has a value between 1 and 10 with the proviso that if n has the value 1 R is a threonine residue or a serine residue and if n has a value between 2 and 10 the peptide contains at least one threonine or serine residue, m has a value between 2 and 4 and at least 20 mol % of the ingredient is N-acetyl-neuraminic acid.
摘要翻译: 包含糖基化氨基酸的寡糖成分和通式RnSacm的肽,其中R是氨基酸残基,Sac是选自N-乙酰 - 神经氨酸,N-乙酰半乳糖胺和半乳糖的单糖,n具有在 1和10,条件是如果n具有值1,R是苏氨酸残基或丝氨酸残基,如果n具有2至10的值,则肽含有至少一个苏氨酸或丝氨酸残基,m具有在2和 4和至少20mol%的成分是N-乙酰神经氨酸。
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公开(公告)号:US20120045566A1
公开(公告)日:2012-02-23
申请号:US13203867
申请日:2009-03-04
CPC分类号: C07H3/04 , A23L33/10 , A23L33/40 , A23V2002/00 , C07H3/06 , A23V2250/28 , A23V2250/70 , A23V2250/156 , A23V2200/322
摘要: An oligosaccharide ingredient comprising glycosylated amino acids and peptides of the general formula RnSacm where R is an amino acid residue, Sac is a monosaccharide selected from the group comprising N-acetyl-neuraminic acid, N-acetyl galactosamine and galactose, n has a value between 1 and 10 with the proviso that if n has the value 1 R is a threonine residue or a serine residue and if n has a value between 2 and 10 the peptide contains at least one threonine or serine residue, m has a value between 2 and 4 and at least 20 mol % of the ingredient is N-acetyl-neuraminic acid.
摘要翻译: 包含糖基化氨基酸的寡糖成分和通式RnSacm的肽,其中R是氨基酸残基,Sac是选自N-乙酰 - 神经氨酸,N-乙酰半乳糖胺和半乳糖的单糖,n具有在 1和10,条件是如果n具有值1,R是苏氨酸残基或丝氨酸残基,如果n具有2至10的值,则肽含有至少一个苏氨酸或丝氨酸残基,m具有在2和 4和至少20mol%的成分是N-乙酰神经氨酸。
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公开(公告)号:US20110045159A1
公开(公告)日:2011-02-24
申请号:US12919650
申请日:2009-02-25
CPC分类号: A23L1/305 , A23L33/10 , A23L33/17 , A23V2002/00 , C07H3/04 , C07H3/06 , A23V2250/28 , A23V2250/1872 , A23V2250/1874 , A23V2250/702 , A23V2250/71 , A23V2250/7142 , A23V2250/708 , A23V2250/704 , A23V2250/1614 , A23V2250/16 , A23V2250/1582 , A23V2250/1578 , A23V2250/1618 , A23V2250/161 , A23V2250/1612 , A23V2250/1626 , A23V2250/1592 , A23V2250/1598 , A23V2250/1588 , A23V2250/1642
摘要: An oligosaccharide ingredient comprising glycosylated amino acids and peptides of the general formula RnSacm where R is an amino acid residue, Sac is a monosaccharide selected from the group comprising N-acetyl-neuraminic acid, N-acetyl galactosamine and galactose, n has a value between (1) and (10) with the proviso that if n has the value (1) R is a threonine residue or a serine residue and if n has a value between (2) and (10) the peptide contains at least one threonine or serine residue, m has a value between (2) and (4) and at least (20) mol % of the ingredient is N-acetyl-neuraminic acid.
摘要翻译: 包含糖基化氨基酸的寡糖成分和通式RnSacm的肽,其中R是氨基酸残基,Sac是选自N-乙酰 - 神经氨酸,N-乙酰半乳糖胺和半乳糖的单糖,n具有在 (1)和(10),条件是如果n具有值(1),R是苏氨酸残基或丝氨酸残基,如果n具有(2)和(10)之间的值,则肽含有至少一个苏氨酸或 丝氨酸残基,m具有(2)和(4)之间的值,并且至少(20)摩尔%的成分是N-乙酰神经氨酸。
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公开(公告)号:US08617631B2
公开(公告)日:2013-12-31
申请号:US12919650
申请日:2009-02-25
IPC分类号: A23C9/00
CPC分类号: A23L1/305 , A23L33/10 , A23L33/17 , A23V2002/00 , C07H3/04 , C07H3/06 , A23V2250/28 , A23V2250/1872 , A23V2250/1874 , A23V2250/702 , A23V2250/71 , A23V2250/7142 , A23V2250/708 , A23V2250/704 , A23V2250/1614 , A23V2250/16 , A23V2250/1582 , A23V2250/1578 , A23V2250/1618 , A23V2250/161 , A23V2250/1612 , A23V2250/1626 , A23V2250/1592 , A23V2250/1598 , A23V2250/1588 , A23V2250/1642
摘要: An oligosaccharide ingredient comprising glycosylated amino acids and peptides of the general formula RnSacm where R is an amino acid residue, Sac is a monosaccharide selected from the group comprising N-acetyl-neuraminic acid, N-acetyl galactosamine and galactose, n has a value between (1) and (10) with the proviso that if n has the value (1) R is a threonine residue or a serine residue and if n has a value between (2) and (10) the peptide contains at least one threonine or serine residue, m has a value between (2) and (4) and at least (20) mol % of the ingredient is N-acetyl-neuraminic acid.
摘要翻译: 包含糖基化氨基酸的寡糖成分和通式RnSacm的肽,其中R是氨基酸残基,Sac是选自N-乙酰 - 神经氨酸,N-乙酰半乳糖胺和半乳糖的单糖,n具有在 (1)和(10),条件是如果n具有值(1),R是苏氨酸残基或丝氨酸残基,如果n具有(2)和(10)之间的值,则肽含有至少一个苏氨酸或 丝氨酸残基,m具有(2)和(4)之间的值,并且至少(20)摩尔%的成分是N-乙酰神经氨酸。
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