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公开(公告)号:US09492524B2
公开(公告)日:2016-11-15
申请号:US14419925
申请日:2012-08-07
CPC分类号: A61K39/0291 , A61K2039/522 , A61K2039/523 , A61K2039/542 , C12N1/36 , Y02A50/407
摘要: The application relates to a Yersinia pseudotuberculosis cell, which comprises nucleic acid coding for expression of at least one Yersinia pestis Caf1 polypeptide or of at least one antigenic fragment of Yersinia pestis Caf1, more particularly to an attenuated Y. pseudotuberculosis cell, which expresses the Y. pestis capsule. Said Y. pseudotuberculosis cell is exceptionally efficient in protecting against both bubonic plague and pulmonary plague.
摘要翻译: 本申请涉及耶尔森氏杆菌结核分枝杆菌细胞,其包括编码至少一种耶尔森氏疫霉Caf1多肽或至少一种耶尔森氏菌耶氏酵母Caf1的抗原片段的核酸,更具体地说,涉及一种减毒的假结核分枝杆菌细胞,其表达Y 鼠疫菌胶囊。 所述假结核分枝杆菌细胞在保护双歧杆菌和肺瘟疫中非常有效。
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公开(公告)号:US20150202275A1
公开(公告)日:2015-07-23
申请号:US14419925
申请日:2012-08-07
CPC分类号: A61K39/0291 , A61K2039/522 , A61K2039/523 , A61K2039/542 , C12N1/36 , Y02A50/407
摘要: The application relates to a Yersinia pseudotuberculosis cell, which comprises nucleic acid coding for expression of at least one Yersinia pestis Caf1 polypeptide or of at least one antigenic fragment of Yersinia pestis Caf1, more particularly to an attenuated Y. pseudotuberculosis cell, which expresses the Y. pestis capsule. Said Y. pseudotuberculosis cell is exceptionally efficient in protecting against both bubonic plague and pulmonary plague.
摘要翻译: 本申请涉及耶尔森氏杆菌结核分枝杆菌细胞,其包括编码至少一种耶尔森氏疫霉Caf1多肽或至少一种耶尔森氏菌耶氏酵母Caf1的抗原片段的核酸,更具体地说,涉及一种减毒的假结核分枝杆菌细胞,其表达Y 鼠疫菌胶囊。 所述假结核分枝杆菌细胞在保护双歧杆菌和肺瘟疫中非常有效。
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