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公开(公告)号:US20070135444A1
公开(公告)日:2007-06-14
申请号:US11652417
申请日:2007-01-11
IPC分类号: A61K31/506
CPC分类号: A61K31/505 , A61K31/506
摘要: 4-(4-methylpiperazin-1-ylmethyl)-N-[4-methyl-3-(4-pyridin-3-yl)pyrimidin-2-ylamino)phenyl]-benzamide or a pharmaceutical acceptable salt thereof can be used in the treatment of neuroblastoma. The invention also relates to a combination of 4-(4-methylpiperazin-1-ylmethyl)-N-[4-methyl-3-(4-pyridin-3-yl)pyrimidin-2-ylamino)phenyl]-benzamide or a pharmaceutical acceptable salt thereof with one or more antineoplastic agents.
摘要翻译: 4-(4-甲基哌嗪-1-基甲基)-N- [4-甲基-3-(4-吡啶-3-基)嘧啶-2-基氨基)苯基] - 苯甲酰胺或其药学上可接受的盐可用于 治疗神经母细胞瘤。 本发明还涉及4-(4-甲基哌嗪-1-基甲基)-N- [4-甲基-3-(4-吡啶-3-基)嘧啶-2-基氨基)苯基] - 苯甲酰胺或 其药学上可接受的盐与一种或多种抗肿瘤剂。
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公开(公告)号:US20050159426A1
公开(公告)日:2005-07-21
申请号:US10503539
申请日:2003-02-06
IPC分类号: C07D239/553 , A61K31/475 , A61K31/505 , A61K31/506 , A61K31/513 , A61K31/675 , A61K31/704 , A61K31/7048 , A61K33/24 , A61K45/00 , A61P25/00 , A61P35/00 , A61P43/00 , C07D401/04 , C07D519/04 , C07H15/252 , C07H17/04 , A61K31/445 , A01N43/40 , A61K31/11
CPC分类号: A61K31/505 , A61K31/506
摘要: 4-(4-methylpiperazin-1-ylmethyl)-N-[4-methyl-3-(4-pyridin-3-yl)pyrimidin-2-ylamino)phenyl]-benzamide or a pharmaceutical acceptable salt thereof can be used in the treatment of neuroblastoma. The invention also relates to a combination of 4-(4-methylpiperazin-1-ylmethyl)-N-[4-methyl-3-(4-pyridin-3-yl)pyrimidin-2-ylamino)phenyl]-benzamide or a pharmaceutical acceptable salt thereof with one or more antineoplastic agents.
摘要翻译: 4-(4-甲基哌嗪-1-基甲基)-N- [4-甲基-3-(4-吡啶-3-基)嘧啶-2-基氨基)苯基] - 苯甲酰胺或其药学上可接受的盐可用于 治疗神经母细胞瘤。 本发明还涉及4-(4-甲基哌嗪-1-基甲基)-N- [4-甲基-3-(4-吡啶-3-基)嘧啶-2-基氨基)苯基] - 苯甲酰胺或 其药学上可接受的盐与一种或多种抗肿瘤剂。
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