公开(公告)号：US20100069761A1

公开(公告)日：2010-03-18

申请号：US12561960

申请日：2009-09-17

申请人： Edward Karst ,  Joseph Douglas Vandine ,  Charles E. Porges ,  Clark Raymond Baker, JR.

发明人： Edward Karst ,  Joseph Douglas Vandine ,  Charles E. Porges ,  Clark Raymond Baker, JR.

IPC分类号： A61B5/0205 ,  A61B5/021

CPC分类号： A61B5/0806 ,  A61B5/0205 ,  A61B5/029 ,  A61B5/14551 ,  A61B5/4035

摘要： The present disclosure relates, in some embodiments, to devices, systems, and/or methods for collecting, processing, and/or displaying stroke volume and/or cardiac output data. For example, a device for assessing changes in cardiac output and/or stroke volume of a subject receiving airway support may comprise a processor; an airway sensor in communication with the processor, wherein the airway sensor is configured and arranged to sense pressure in the subject's airway, lungs, and/or intrapleural space over time; a blood volume sensor in communication with the processor, wherein the blood volume sensor is configured and arranged to sense pulsatile volume of blood in a tissue of the subject over time; and a display configured and arranged to display a representative of an airway pressure, a pulsatile blood volume, a photoplethysmogram, a photoplethysmogram ratio, the determined cardiac output and/or stroke volume, or combinations thereof. A method of assessing changes in cardiac output or stroke volume of a subject receiving airway support from a breathing assistance system may comprise sensing pressure in the subject's airway as a function of time, sensing pulsatile volume of blood in a tissue of the subject as a function of time, producing a photoplethysmogram from the sensed pulsatile volume, determining the ratio of the amplitude of the photoplethysmogram during inhalation to the amplitude of the photoplethysmogram during exhalation, and determining the change in cardiac output or stroke volume of the subject using the determined ratio.

摘要翻译： 在一些实施例中，本公开涉及用于收集，处理和/或显示搏动体积和/或心输出量数据的装置，系统和/或方法。 例如，用于评估受试者接受气道支持的心输出量和/或卒中体积变化的装置可以包括处理器; 与所述处理器通信的气道传感器，其中所述气道传感器被配置和布置成随时间感测所述受试者的气道，肺和/或胸膜内空​​间中的压力; 与所述处理器通信的血容量传感器，其中所述血液体积传感器被配置和布置成在时间上感测所述受试者的组织中的血液的脉动体积; 以及显示器，被配置和布置成显示气道压力，搏动血液体积，光电积氧图，光电积氧图比例，所确定的心输出量和/或行程体积的代表，或其组合。 评估来自呼吸辅助系统的受试者接受呼吸道支持的受试者的心输出量或中风体积变化的方法可以包括感测受试者的气道中的压力作为时间的函数，感测作为一个功能的受试者的组织中的血液的脉动体积 的时间，从感测到的脉动体积产生光电积氧图，确定吸入期间的光电积氧图的振幅与呼气期间的光谱脉搏波幅度的比率，以及使用确定的比例确定受试者的心输出量或中风体积的变化。

公开(公告)号：US08551006B2

公开(公告)日：2013-10-08

申请号：US12561960

申请日：2009-09-17

申请人： Edward Karst ,  Joseph Douglas Vandine ,  Charles E. Porges ,  Clark Raymond Baker, Jr.

发明人： Edward Karst ,  Joseph Douglas Vandine ,  Charles E. Porges ,  Clark Raymond Baker, Jr.

IPC分类号： A61B5/08

CPC分类号： A61B5/0806 ,  A61B5/0205 ,  A61B5/029 ,  A61B5/14551 ,  A61B5/4035

摘要： The present disclosure relates, in some embodiments, to devices, systems, and/or methods for collecting, processing, and/or displaying stroke volume and/or cardiac output data. For example, a device for assessing changes in cardiac output and/or stroke volume of a subject receiving airway support may comprise a processor; an airway sensor in communication with the processor, wherein the airway sensor is configured and arranged to sense pressure in the subject's airway, lungs, and/or intrapleural space over time; a blood volume sensor in communication with the processor, wherein the blood volume sensor is configured and arranged to sense pulsatile volume of blood in a tissue of the subject over time; and a display configured and arranged to display a representative of an airway pressure, a pulsatile blood volume, a photoplethysmogram, a photoplethysmogram ratio, the determined cardiac output and/or stroke volume, or combinations thereof. A method of assessing changes in cardiac output or stroke volume of a subject receiving airway support from a breathing assistance system may comprise sensing pressure in the subject's airway as a function of time, sensing pulsatile volume of blood in a tissue of the subject as a function of time, producing a photoplethysmogram from the sensed pulsatile volume, determining the ratio of the amplitude of the photoplethysmogram during inhalation to the amplitude of the photoplethysmogram during exhalation, and determining the change in cardiac output or stroke volume of the subject using the determined ratio.

摘要翻译： 在一些实施例中，本公开涉及用于收集，处理和/或显示搏动体积和/或心输出量数据的装置，系统和/或方法。 例如，用于评估受试者接受气道支持的心输出量和/或卒中体积变化的装置可以包括处理器; 与所述处理器通信的气道传感器，其中所述气道传感器被配置和布置成随时间感测所述受试者的气道，肺和/或胸膜内空​​间中的压力; 与所述处理器通信的血容量传感器，其中所述血液体积传感器被配置和布置成在时间上感测所述受试者的组织中的血液的脉动体积; 以及显示器，被配置和布置成显示气道压力，搏动血液体积，光电积氧图，光电积氧图比例，所确定的心输出量和/或行程体积的代表，或其组合。 评估来自呼吸辅助系统的受试者接受呼吸道支持的受试者的心输出量或中风体积变化的方法可以包括感测受试者的气道中的压力作为时间的函数，感测作为一个功能的受试者的组织中的血液的脉动体积 的时间，从感测到的脉动体积产生光电积氧图，确定吸入期间的光谱体积描记图的幅度与呼出期间的光谱脉搏波幅度的比率，以及使用所确定的比例确定受试者的心输出量或中风体积的变化。