公开(公告)号：US20130317480A1

公开(公告)日：2013-11-28

申请号：US13989556

申请日：2011-12-01

申请人： Dominic Charles Reber ,  Congyi Huang ,  Matthew Young

发明人： Dominic Charles Reber ,  Congyi Huang ,  Matthew Young

IPC分类号： A61M5/20

CPC分类号： A61M5/2033 ,  A61M5/3204 ,  A61M2005/2013 ,  A61M2005/2073 ,  Y10T29/53

摘要： The invention provides a drive mechanism for an autoinjector, configured to be coupled to a drug containing portion to form a complete autoinjector, the drive mechanism comprising: a housing (20); a drive means coupled to the housing, the drive means comprising a resilient member (22); a retaining means coupled to the housing, the retaining means (60) engaging the drive means in a first position to retain the resilient member in a deformed condition, and releasing the drive means in a second position; and a coupling means (24) for coupling with a drug containing portion (10). The drug containing portion retains the drive means in a second deformed condition when the retaining means is in the second position, the drive means storing enough energy in the second deformed condition to drive needle insertion and/or drug delivery.

摘要翻译： 本发明提供了一种用于自动注射器的驱动机构，其配置为联接到药物容纳部分以形成完整的自动注射器，所述驱动机构包括：壳体（20）; 联接到所述壳体的驱动装置，所述驱动装置包括弹性构件（22）; 保持装置，联接到壳体，保持装置（60）在第一位置接合驱动装置，以将弹性构件保持在变形状态，并将驱动装置释放在第二位置; 以及用于与药物容纳部分（10）联接的联接装置（24）。 当保持装置处于第二位置时，药物容纳部分将驱动装置保持在第二变形状态，驱动装置在第二变形状态下存储足够的能量以驱动针插入和/或药物递送。

公开(公告)号：US10406288B2

公开(公告)日：2019-09-10

申请号：US13989551

申请日：2011-12-01

申请人： Dominic Charles Reber ,  Congyi Huang ,  Matthew Young

发明人： Dominic Charles Reber ,  Congyi Huang ,  Matthew Young

IPC分类号： A61M5/20

摘要： The invention provides a delivery mechanism for an autoinjector comprising: a first drive member configured to drive a first component in an axial direction; a second drive member configured to drive a second component in an axial direction; and a release mechanism configured to control a sequence of release of the first drive member and the second drive member, wherein the release mechanism is positioned at least partially within the first or second drive member.

公开(公告)号：US20180117291A1

公开(公告)日：2018-05-03

申请号：US15699382

申请日：2017-09-08

申请人： Zita S. NETZEL ,  Gary STACEY ,  Alexander David NORMAN ,  Congyi HUANG ,  Timothy Charles FREARSON ,  Charles Frazer KILBY ,  Patrick H. RUANE ,  Alan J. LEVY ,  Kevin W. GELSTON ,  Jennifer DARMOUR ,  Jenny E. HAPGOOD ,  David Evans ROTH ,  Ronald A. OVERBECK ,  Ling-Kang TONG

发明人： Zita S. NETZEL ,  Gary STACEY ,  Alexander David NORMAN ,  Congyi HUANG ,  Timothy Charles FREARSON ,  Charles Frazer KILBY ,  Patrick H. RUANE ,  Alan J. LEVY ,  Kevin W. GELSTON ,  Jennifer DARMOUR ,  Jenny E. HAPGOOD ,  David Evans ROTH ,  Ronald A. OVERBECK ,  Ling-Kang TONG

IPC分类号： A61M35/00

CPC分类号： A61M35/00 ,  A61M5/14244 ,  A61M5/14248 ,  A61M5/145 ,  A61M5/1456 ,  A61M5/16877 ,  A61M5/16881 ,  A61M2005/14268 ,  A61M2005/14506 ,  A61M2005/14573

摘要： A two-part bioactive agent delivery system, the system including a disposable part comprising an agent reservoir, a bolus chamber, the volume of the bolus chamber being less than the volume of the agent reservoir, an agent outlet, and a valve having a first position communicating the agent reservoir with the bolus chamber and a second position communicating the bolus chamber with the outlet; and a reusable part including a valve driver, a power source and control electronics, the control electronics being adapted to control the valve driver to actuate the valve to deliver bioactive agent from the agent reservoir to the agent outlet; the system further having a spring extending between the agent reservoir piston and a surface of the reusable part or of the disposable part to pressurize the agent reservoir when the spring is compressed and the agent reservoir contains a quantity of bioactive agent.

公开(公告)号：US20160220798A1

公开(公告)日：2016-08-04

申请号：US15009683

申请日：2016-01-28

申请人： Zita S. NETZEL ,  Gary STACEY ,  Alexander David NORMAN ,  Congyi HUANG ,  Timothy Charles FREARSON ,  Charles Frazer KILBY ,  Patrick H. RUANE ,  Alan J. LEVY ,  Kevin W. GELSTON ,  Jennifer DARMOUR ,  Jenny E. HAPGOOD ,  David Evans ROTH ,  Ronald A. OVERBECK ,  Ling-Kang TONG

发明人： Zita S. NETZEL ,  Gary STACEY ,  Alexander David NORMAN ,  Congyi HUANG ,  Timothy Charles FREARSON ,  Charles Frazer KILBY ,  Patrick H. RUANE ,  Alan J. LEVY ,  Kevin W. GELSTON ,  Jennifer DARMOUR ,  Jenny E. HAPGOOD ,  David Evans ROTH ,  Ronald A. OVERBECK ,  Ling-Kang TONG

IPC分类号： A61M35/00

CPC分类号： A61M35/00 ,  A61M5/14244 ,  A61M5/14248 ,  A61M5/145 ,  A61M5/1456 ,  A61M5/16877 ,  A61M5/16881 ,  A61M2005/14268 ,  A61M2005/14506 ,  A61M2005/14573

摘要： A two-part bioactive agent delivery system, the system including a disposable part comprising an agent reservoir, a bolus chamber, the volume of the bolus chamber being less than the volume of the agent reservoir, an agent outlet, and a valve having a first position communicating the agent reservoir with the bolus chamber and a second position communicating the bolus chamber with the outlet; and a reusable part including a valve driver, a power source and control electronics, the control electronics being adapted to control the valve driver to actuate the valve to deliver bioactive agent from the agent reservoir to the agent outlet; the system further having a spring extending between the agent reservoir piston and a surface of the reusable part or of the disposable part to pressurize the agent reservoir when the spring is compressed and the agent reservoir contains a quantity of bioactive agent.

摘要翻译： 一种两部分生物活性剂递送系统，该系统包括一次性部分，其包括药剂储存器，推注室，推注室的体积小于药剂储存器的体积，药剂出口和具有第一 将药剂储存器与推注室连通的位置和将推注室与出口连通的第二位置; 以及包括阀驱动器，电源和控制电子器件的可再利用部件，所述控制电子器件适于控制所述阀驱动器致动所述阀以将生物活性剂从所述试剂储存器输送到所述试剂出口; 所述系统还具有弹簧，所述弹簧在所述药剂储存器活塞与所述可重复使用部件或所述一次性部件的表面之间延伸，以在所述弹簧被压缩并且所述药剂储存器包含一定数量的生物活性剂时对所述药剂储存器加压。

公开(公告)号：US20140046259A1

公开(公告)日：2014-02-13

申请号：US13989551

申请日：2011-12-01

申请人： Dominic Charles Reber ,  Congyi Huang ,  Matthew Young

发明人： Dominic Charles Reber ,  Congyi Huang ,  Matthew Young

IPC分类号： A61M5/20

CPC分类号： A61M5/2033 ,  A61M2005/2013 ,  A61M2005/206 ,  A61M2205/581

摘要： The invention provides a delivery mechanism for an autoinjector comprising: a first drive member configured to drive a first component in an axial direction; a second drive member configured to drive a second component in an axial direction; and a release mechanism configured to control a sequence of release of the first drive member and the second drive member, wherein the release mechanism is positioned at least partially within the first or second drive member.

摘要翻译： 本发明提供了一种用于自动注射器的输送机构，包括：构造成在轴向方向上驱动第一部件的第一驱动部件; 第二驱动构件，构造成沿轴向驱动第二部件; 以及释放机构，其构造成控制所述第一驱动构件和所述第二驱动构件的释放序列，其中所述释放机构至少部分地位于所述第一或第二驱动构件内。

公开(公告)号：US10166335B2

公开(公告)日：2019-01-01

申请号：US13989556

申请日：2011-12-01

申请人： Dominic Charles Reber ,  Congyi Huang ,  Matthew Young

发明人： Dominic Charles Reber ,  Congyi Huang ,  Matthew Young

IPC分类号： A61M5/20 ,  A61M5/32

摘要： The invention provides a drive mechanism for an autoinjector, configured to be coupled to a drug containing portion to form a complete autoinjector, the drive mechanism comprising: a housing (20); a drive means coupled to the housing, the drive means comprising a resilient member (22); a retaining means coupled to the housing, the retaining means (60) engaging the drive means in a first position to retain the resilient member in a deformed condition, and releasing the drive means in a second position; and a coupling means (24) for coupling with a drug containing portion (10). The drug containing portion retains the drive means in a second deformed condition when the retaining means is in the second position, the drive means storing enough energy in the second deformed condition to drive needle insertion and/or drug delivery.

公开(公告)号：USD671638S1

公开(公告)日：2012-11-27

申请号：US29406538

申请日：2011-11-16

申请人： Matthew Young ,  Jose Alberto De Los Rios ,  Congyi Huang

设计人： Matthew Young ,  Jose Alberto De Los Rios ,  Congyi Huang