公开(公告)号：US20060281154A1

公开(公告)日：2006-12-14

申请号：US10564741

申请日：2004-07-14

申请人： Giuseppe Molteni ,  Cristina Formantici ,  Cristina Demarchi ,  Yves Galante ,  Giuseppe Libassi

发明人： Giuseppe Molteni ,  Cristina Formantici ,  Cristina Demarchi ,  Yves Galante ,  Giuseppe Libassi

IPC分类号： C12P19/04 ,  A61K31/716

CPC分类号： C08B11/20 ,  C12P19/14

摘要： The present invention refers to the procedure for the preparation of aqueous concentrated solutions of low viscosity carboxymethylcellulose by enzymatic depolymerisation of medium viscosity carboxymethylcellulose in the form of dispersed powder in a hydro-alcoholic heterogeneous medium, and to such aqueous concentrated solutions which have Brookfield viscosity, at 20° C. and 20 rpm, comprised between 2000 and 5000 mPa*s. Preferred alcohol-water biphasic systems have from 40% to 50% of alcohol (e.g., ethanol or isopropanol). The aqueous solutions of carboxymethylcellulose produced are stable over time, and their viscosity varies no more than 10% in 3 months.

摘要翻译： 本发明涉及通过在分散粉末形式的中等粘度的羧甲基纤维素在含水异构介质中的酶促解聚制备低粘度羧甲基纤维素水溶液的方法，以及具有布鲁克菲尔德粘度的这种水性浓缩溶液， 在20℃和20rpm下，包括在2000和5000mPa * s之间。 优选的醇 - 水双相系统具有40％至50％的醇（例如乙醇或异丙醇）。 生产的羧甲基纤维素水溶液随时间稳定，3个月内粘度变化不超过10％。