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公开(公告)号：US09216229B2
公开(公告)日：2015-12-22
申请号：US13904432
申请日：2013-05-29
申请人： Alan Daniel Brown , Brian Robert Champion , Clare Lees , David Paul Gervais , Lyn Howard Jones , Anne Maria Kristina Kjerrstrom , David Cameron Pryde , Lee Richard Roberts , David Michael Wyatt
发明人： Alan Daniel Brown , Brian Robert Champion , Clare Lees , David Paul Gervais , Lyn Howard Jones , Anne Maria Kristina Kjerrstrom , David Cameron Pryde , Lee Richard Roberts , David Michael Wyatt
IPC分类号： A61K38/04 , A61K47/48 , A61K39/00 , A61K39/395
CPC分类号： A61K47/48338 , A61K39/00 , A61K39/395 , A61K47/643 , A61K47/646 , A61K2039/505 , A61K2039/6075 , A61K2039/627
摘要： The present invention relates to the provision of novel immunogens comprising an antigenic IgE peptide preferably linked to an immunogenic carrier for the prevention, treatment or alleviation of IgE-mediated disorders. The invention further relates to methods for production of these medicaments, immunogenic compositions and pharmaceutical compositing thereof and their use in medicine.
摘要翻译： 本发明涉及提供新型免疫原，其包含抗原性IgE肽，优选与免疫原性载体连接以预防，治疗或减轻IgE介导的病症。 本发明还涉及这些药物的生产方法，免疫原性组合物及其药物合成及其在药物中的用途。
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公开(公告)号：US20100158933A1
公开(公告)日：2010-06-24
申请号：US12634336
申请日：2009-12-09
申请人： ALAN DANIEL BROWN , BRIAN ROBERT CHAMPION , CLARE CHRISTY , DAVID PAUL GERVAIS , LYN HOWARD JONES , ANNE MARIA KRISTINA KJERRSTROM , DAVID CAMERON PRYDE , LEE RICHARD ROBERTS , DAVID MICHAEL WYATT
发明人： ALAN DANIEL BROWN , BRIAN ROBERT CHAMPION , CLARE CHRISTY , DAVID PAUL GERVAIS , LYN HOWARD JONES , ANNE MARIA KRISTINA KJERRSTROM , DAVID CAMERON PRYDE , LEE RICHARD ROBERTS , DAVID MICHAEL WYATT
CPC分类号： A61K47/48338 , A61K39/00 , A61K39/395 , A61K47/643 , A61K47/646 , A61K2039/505 , A61K2039/6075 , A61K2039/627
摘要： The present invention relates to the provision of novel immunogens comprising an antigenic IgE peptide preferably linked to an immunogenic carrier for the prevention, treatment or alleviation of IgE-mediated disorders. The invention further relates to methods for production of these medicaments, immunogenic compositions and pharmaceutical compositing thereof and their use in medicine.
摘要翻译： 本发明涉及提供新型免疫原，其包含抗原性IgE肽，优选与免疫原性载体连接以预防，治疗或减轻IgE介导的病症。 本发明还涉及这些药物的生产方法，免疫原性组合物及其药物合成及其在药物中的用途。
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公开(公告)号：US20140017239A1
公开(公告)日：2014-01-16
申请号：US13904432
申请日：2013-05-29
申请人： Alan Daniel Brown , Brian Robert Champion , Clare Christy , David Paul Gervais , Lyn Howard Jones , Anne Maria Kristina Kjerrstrom , David Cameron Pryde , Lee Richard Roberts , David Michael Wyatt
发明人： Alan Daniel Brown , Brian Robert Champion , Clare Christy , David Paul Gervais , Lyn Howard Jones , Anne Maria Kristina Kjerrstrom , David Cameron Pryde , Lee Richard Roberts , David Michael Wyatt
IPC分类号： A61K47/48 , A61K39/395
CPC分类号： A61K47/48338 , A61K39/00 , A61K39/395 , A61K47/643 , A61K47/646 , A61K2039/505 , A61K2039/6075 , A61K2039/627
摘要： The present invention relates to the provision of novel immunogens comprising an antigenic IgE peptide preferably linked to an immunogenic carrier for the prevention, treatment or alleviation of IgE-mediated disorders. The invention further relates to methods for production of these medicaments, immunogenic compositions and pharmaceutical compositing thereof and their use in medicine.
摘要翻译： 本发明涉及提供新型免疫原，其包含抗原性IgE肽，优选与免疫原性载体连接以预防，治疗或减轻IgE介导的病症。 本发明还涉及这些药物的生产方法，免疫原性组合物及其药物合成及其在药物中的用途。
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公开(公告)号：US20120294848A1
公开(公告)日：2012-11-22
申请号：US13564103
申请日：2012-08-01
申请人： Alan Daniel Brown , Brian Robert Champion , Clare Christy , David Paul Gervais , Lyn Howard Jones , Anne Maria Kristina Kjerrstrom , David Cameron Pryde , Lee Richard Roberts , David Michael Wyatt
发明人： Alan Daniel Brown , Brian Robert Champion , Clare Christy , David Paul Gervais , Lyn Howard Jones , Anne Maria Kristina Kjerrstrom , David Cameron Pryde , Lee Richard Roberts , David Michael Wyatt
IPC分类号： C07K17/00 , A61K39/395 , A61P37/02 , C07K16/00
CPC分类号： A61K47/48338 , A61K39/00 , A61K39/395 , A61K47/643 , A61K47/646 , A61K2039/505 , A61K2039/6075 , A61K2039/627
摘要： The present invention relates to the provision of novel immunogens comprising an antigenic IgE peptide preferably linked to an immunogenic carrier for the prevention, treatment or alleviation of IgE-mediated disorders. The invention further relates to methods for production of these medicaments, immunogenic compositions and pharmaceutical compositing thereof and their use in medicine.
摘要翻译： 本发明涉及提供新型免疫原，其包含抗原性IgE肽，优选与免疫原性载体连接以预防，治疗或减轻IgE介导的病症。 本发明还涉及这些药物的生产方法，免疫原性组合物及其药物合成及其在药物中的用途。
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公开(公告)号：US20100204455A1
公开(公告)日：2010-08-12
申请号：US12670733
申请日：2008-07-18
摘要： The present invention relates to a method of purification of antibodies. An object of the present invention is to provide a method for the isolation of antibodies from a solution containing one or more antibodies, comprising the steps of precipitating the antibody and washing the solid precipitate with washing buffer. Preferably, the antibody is precipitated by using a PEG solution or sodium phosphate.
摘要翻译： 本发明涉及一种纯化抗体的方法。 本发明的目的是提供一种从含有一种或多种抗体的溶液中分离抗体的方法，其包括沉淀抗体并用洗涤缓冲液洗涤固体沉淀物的步骤。 优选地，通过使用PEG溶液或磷酸钠沉淀抗体。
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公开(公告)号：US08475801B2
公开(公告)日：2013-07-02
申请号：US13564103
申请日：2012-08-01
申请人： Alan Daniel Brown , Brian Robert Champion , Clare Christy , David Paul Gervais , Lyn Howard Jones , Anne Maria Kristina Kjerrstrom , David Cameron Pryde , Lee Richard Roberts , David Michael Wyatt
发明人： Alan Daniel Brown , Brian Robert Champion , Clare Christy , David Paul Gervais , Lyn Howard Jones , Anne Maria Kristina Kjerrstrom , David Cameron Pryde , Lee Richard Roberts , David Michael Wyatt
IPC分类号： A61K39/00
CPC分类号： A61K47/48338 , A61K39/00 , A61K39/395 , A61K47/643 , A61K47/646 , A61K2039/505 , A61K2039/6075 , A61K2039/627
摘要： The present invention relates to the provision of novel immunogens comprising an antigenic IgE peptide preferably linked to an immunogenic carrier for the prevention, treatment or alleviation of IgE-mediated disorders. The invention further relates to methods for production of these medicaments, immunogenic compositions and pharmaceutical compositing thereof and their use in medicine.
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公开(公告)号：US08298547B2
公开(公告)日：2012-10-30
申请号：US12634336
申请日：2009-12-09
申请人： Alan Daniel Brown , Brian Robert Champion , Clare Christy , David Paul Gervais , Lyn Howard Jones , Anne Maria Kristina Kjerrstrom , David Cameron Pryde , Lee Richard Roberts , David Michael Wyatt
发明人： Alan Daniel Brown , Brian Robert Champion , Clare Christy , David Paul Gervais , Lyn Howard Jones , Anne Maria Kristina Kjerrstrom , David Cameron Pryde , Lee Richard Roberts , David Michael Wyatt
IPC分类号： A61K39/00
CPC分类号： A61K47/48338 , A61K39/00 , A61K39/395 , A61K47/643 , A61K47/646 , A61K2039/505 , A61K2039/6075 , A61K2039/627
摘要： The present invention relates to the provision of novel immunogens comprising an antigenic IgE peptide preferably linked to an immunogenic carrier for the prevention, treatment or alleviation of IgE-mediated disorders. The invention further relates to methods for production of these medicaments, immunogenic compositions and pharmaceutical compositing thereof and their use in medicine.
摘要翻译： 本发明涉及提供新型免疫原，其包含抗原性IgE肽，优选与免疫原性载体连接以预防，治疗或减轻IgE介导的病症。 本发明还涉及这些药物的生产方法，免疫原性组合物及其药物合成及其在药物中的用途。
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