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公开(公告)号:US11478442B2
公开(公告)日:2022-10-25
申请号:US16910770
申请日:2020-06-24
申请人: DS Biopharma Limited
发明人: Mehar Manku , John Climax , David Coughlan , James Dunne
IPC分类号: A61K31/202 , A61K9/48 , A61K9/00 , A61P17/00 , A61Q19/00 , A61K8/11 , A61K8/65 , A61K8/36 , A61K31/201 , A61P17/04
摘要: The present disclosure provides orally deliverable pharmaceutical compositions comprising DGLA and to methods of using same to treat a variety of conditions and disorders.
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2.
公开(公告)号:US20220324788A1
公开(公告)日:2022-10-13
申请号:US17527440
申请日:2021-11-16
申请人: DS Biopharma Limited
发明人: Mehar Manku , John Climax , David Coughlan
IPC分类号: C07C59/76 , A61K45/06 , A61K31/202 , A61K31/232
摘要: The present disclosure provides 15-oxo-EPA and 15-oxo-DGLA, compositions comprising 15-oxo-EPA and/or 15-oxo-DGLA, and methods of treating and/or preventing fibrosis, skin disorders, inflammation, kidney disease or renal dysfunction in a subject in need thereof by administering 15-oxo-EPA and/or 15-oxo-DGLA.
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公开(公告)号:US10918614B2
公开(公告)日:2021-02-16
申请号:US16450187
申请日:2019-06-24
申请人: DS Biopharma Limited
发明人: Adam Kelliher , Angus Morrison , Phil Knowles
IPC分类号: A61K31/202 , A61K31/573 , A61K45/06 , C07C59/42 , A61K9/00
摘要: The present invention provides a compound which is a polyunsaturated fatty acid (PUFA) derivative of formula (I), or a pharmaceutically acceptable salt, or solvate thereof, for use in treating various skin disorders.
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公开(公告)号:US20190314317A1
公开(公告)日:2019-10-17
申请号:US16450187
申请日:2019-06-24
申请人: DS Biopharma Limited
发明人: Adam Kelliher , Angus Morrison , Phil Knowles
IPC分类号: A61K31/202 , C07C59/42 , A61K31/573 , A61K45/06 , A61K9/00
摘要: The present invention provides a compound which is a polyunsaturated fatty acid (PUFA) derivative of formula (I), or a pharmaceutically acceptable salt, or solvate thereof, for use in treating various skin disorders.
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公开(公告)号:US20180036272A1
公开(公告)日:2018-02-08
申请号:US15661374
申请日:2017-07-27
申请人: DS Biopharma Limited
发明人: Mehar Manku , John Climax , David Coughlan , James Dunne
CPC分类号: A61K31/202 , A61K8/11 , A61K8/361 , A61K8/65 , A61K9/0053 , A61K9/48 , A61K9/4825 , A61Q19/00
摘要: The present disclosure provides orally deliverable pharmaceutical compositions comprising DGLA and to methods of using same to treat a variety of conditions and disorders.
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公开(公告)号:US20210322354A1
公开(公告)日:2021-10-21
申请号:US17106348
申请日:2020-11-30
申请人: DS Biopharma Limited
发明人: John Climax , David Coughlan , Markus Weissbach , Moayed Hamza
IPC分类号: A61K31/202 , A61P17/00 , A61P37/06
摘要: The present disclosure provides orally and/or topically deliverable pharmaceutical compositions comprising DGLA or a derivative thereof and/or 15-HETrE or a derivative thereof and methods of using same to treat a variety of conditions, diseases, and disorders, including but not limited to inflammatory, fibrotic, and proliferative conditions, diseases, and disorders.
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公开(公告)号:US20200323807A1
公开(公告)日:2020-10-15
申请号:US16910770
申请日:2020-06-24
申请人: DS Biopharma Limited
发明人: Mehar Manku , John Climax , David Coughlan , James Dunne
IPC分类号: A61K31/202 , A61K9/48 , A61K9/00 , A61Q19/00 , A61K8/11 , A61K8/65 , A61K8/36 , A61P17/00 , A61K31/201 , A61P17/04
摘要: The present disclosure provides orally deliverable pharmaceutical compositions comprising DGLA and to methods of using same to treat a variety of conditions and disorders.
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8.
公开(公告)号:US10570083B2
公开(公告)日:2020-02-25
申请号:US15921211
申请日:2018-03-14
申请人: DS Biopharma Limited
发明人: Mehar Manku , John Climax , David Coughlan
IPC分类号: A61K31/202 , A61K31/232 , C07C59/76 , A61K45/06
摘要: The present disclosure provides 15-oxo-EPA and 15-oxo-DGLA, compositions comprising 15-oxo-EPA and/or 15-oxo-DGLA, and methods of treating and/or preventing fibrosis, skin disorders, inflammation, kidney disease or renal dysfunction in a subject in need thereof by administering 15-oxo-EPA and/or 15-oxo-DGLA.
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公开(公告)号:US20190269639A1
公开(公告)日:2019-09-05
申请号:US16279794
申请日:2019-02-19
申请人: DS Biopharma Limited
发明人: Mehar Manku , John Climax , David Coughlan , James Dunne
IPC分类号: A61K31/201 , A61K9/48 , A61K9/00 , A61P17/00
摘要: The present disclosure provides orally deliverable pharmaceutical compositions comprising DGLA and to methods of using same to treat a variety of conditions and disorders.
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公开(公告)号:US10328046B2
公开(公告)日:2019-06-25
申请号:US15856254
申请日:2017-12-28
申请人: DS Biopharma Limited
发明人: Adam Kelliher , Angus Morrison , Phil Knowles
IPC分类号: A61K9/00 , A61K45/06 , A61K31/202 , A61K31/573
摘要: The present invention provides a compound which is a polyunsaturated fatty acid (PUFA) derivative of formula (I), or a pharmaceutically acceptable salt, or solvate thereof, for use in treating various skin disorders.
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