公开(公告)号：US20250066428A1

公开(公告)日：2025-02-27

申请号：US18779855

申请日：2024-07-22

Applicant: DYNO THERAPEUTICS, INC.

Inventor： Ina Chen ,  Jeff Gerold ,  Jerrah Holth ,  Sylvain Lapan ,  Kathy S. Lin ,  Samuel Wolock

IPC: C07K14/015 ,  A61K48/00 ,  C12N15/86

Abstract: The disclosure is directed in part to variant capsid polypeptides that can be used to deliver payloads.

公开(公告)号：US20240417430A1

公开(公告)日：2024-12-19

申请号：US18788938

申请日：2024-07-30

Applicant: DYNO THERAPEUTICS, INC.

Inventor： Ina Chen ,  Jeff Gerold ,  Jerrah Holth ,  Sylvain Lapan ,  Kathy S. Lin ,  Samuel Wolock

IPC: C07K14/015 ,  A61K48/00 ,  C12N15/86

Abstract: The disclosure is directed in part to variant capsid polypeptides that can be used to deliver payloads.

公开(公告)号：US20240368228A1

公开(公告)日：2024-11-07

申请号：US18566272

申请日：2022-06-02

Applicant: DYNO THERAPEUTICS, INC.

Inventor： Sylvain Lapan ,  Hanna Levitin ,  Lauren Wheelock

IPC: C07K14/005 ,  A61K48/00 ,  C12N15/86

Abstract: The disclosure is directed in part to variant capsid polypeptides that can be used to deliver payloads.

公开(公告)号：US20240294578A1

公开(公告)日：2024-09-05

申请号：US18573582

申请日：2022-06-22

Applicant: DYNO THERAPEUTICS, INC.

Inventor： Sylvain Lapan ,  Hanna Levitin

IPC: C07K14/005 ,  A61K48/00 ,  C12N15/86

CPC classification number: C07K14/005 ,  A61K48/0025 ,  A61K48/0091 ,  C12N15/86 ,  C12N2750/14122 ,  C12N2750/14142 ,  C12N2750/14143

Abstract: The disclosure is directed in part to variant capsid polypeptides that can be used to deliver pay loads.

公开(公告)号：US20230357326A1

公开(公告)日：2023-11-09

申请号：US18323135

申请日：2023-05-24

Applicant: DYNO THERAPEUTICS, INC.

Inventor： Ina Chen ,  Jeff Gerold ,  Jerrah Holth ,  Sylvain Lapan ,  Kathy S. Lin ,  Samuel Wolock

IPC: C07K14/015 ,  C12N15/86 ,  A61K48/00

CPC classification number: C07K14/015 ,  C12N15/86 ,  A61K48/0058 ,  C12N2750/14122 ,  C12N2750/14143 ,  C12N2750/14145

Abstract: The disclosure is directed in part to variant capsid polypeptides that can be used to deliver payloads.

公开(公告)号：US20240425552A1

公开(公告)日：2024-12-26

申请号：US18790657

申请日：2024-07-31

Applicant: DYNO THERAPEUTICS, INC.

Inventor： Ina Chen ,  Jeff Gerold ,  Jerrah Holth ,  Sylvain Lapan ,  Kathy S. Lin ,  Samuel Wolock

IPC: C07K14/015 ,  A61K48/00 ,  C12N15/86

Abstract: The disclosure is directed in part to variant capsid polypeptides that can be used to deliver payloads.

公开(公告)号：US12116385B2

公开(公告)日：2024-10-15

申请号：US18323135

申请日：2023-05-24

Applicant: DYNO THERAPEUTICS, INC.

Inventor： Ina Chen ,  Jeff Gerold ,  Jerrah Holth ,  Sylvain Lapan ,  Kathy S. Lin ,  Samuel Wolock

IPC: C12N7/00 ,  A61K48/00 ,  C07K14/015 ,  C12N15/86

CPC classification number: C07K14/015 ,  A61K48/0058 ,  C12N15/86 ,  C12N2750/14122 ,  C12N2750/14143 ,  C12N2750/14145

Abstract: The disclosure is directed in part to variant capsid polypeptides that can be used to deliver payloads.

公开(公告)号：US20240287141A1

公开(公告)日：2024-08-29

申请号：US18571384

申请日：2022-06-17

Applicant: DYNO THERAPEUTICS, INC.

Inventor： Sylvain Lapan ,  Hanna Levitin

IPC: C07K14/005 ,  A61K48/00 ,  C12N15/86

CPC classification number: C07K14/005 ,  A61K48/0075 ,  C12N15/86 ,  C12N2750/14122 ,  C12N2750/14143

Abstract: The disclosure is directed in part to variant capsid polypeptides that can be used to deliver payloads.

公开(公告)号：US20240277869A1

公开(公告)日：2024-08-22

申请号：US18571367

申请日：2022-06-17

Applicant: DYNO THERAPEUTICS, INC.

Inventor： Sylvain Lapan ,  Hanna Levitin

IPC: A61K48/00 ,  C07K14/005 ,  C12N7/00

CPC classification number: A61K48/0041 ,  C07K14/005 ,  C12N7/00 ,  C12N2750/14122 ,  C12N2750/14151

Abstract: The disclosure is directed in part to variant capsid polypeptides that can be used to deliver payloads.

公开(公告)号：US20230357324A1

公开(公告)日：2023-11-09

申请号：US18042890

申请日：2021-08-26

Applicant: DYNO THERAPEUTICS, INC.

Inventor： Jeffrey GEROLD ,  Eric KELSIC ,  Sam SINAI ,  Adrian VERES ,  Samuel WOLOCK

IPC: C07K14/005

CPC classification number: C07K14/005 ,  C12N2750/14122 ,  C12N2750/14151 ,  C12N2750/14143 ,  C12N2840/50

Abstract: The disclosure is directed in part to improved methods of making dependoparvovirus particles utilizing a nucleic acid comprising an open reading from encoding membrane-associated accessory protein (MAAP) comprising an exogenous start codon.