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1.发明授权Polymerization products containing amino groups useful in serum cholesterol level control 失效含有氨基的聚合产物可用于血清胆固醇水平控制
公开(公告)号：US3980770A
公开(公告)日：1976-09-14
申请号：US529987
申请日：1974-12-05
CPC分类号： B01J41/14 , A61K31/785 , C08G59/5033
摘要： A pharmaceutical product containing amino groups, which product:A. is comprised of residues of one or more diamines of the general formulaH.sub.2 N.CH.sub.2. phenylene.CH.sub.2.NH.sub.2 (I)which residues are interconnected by bridges between the residues to form a three-dimensional network, the bridges being bound to nitrogen atoms in the residues (I) and comprise straight or branched aliphatic, saturated hydrocarbon chains substituted with one or more hydroxyl groups and containing 3-30 carbon atoms, preferably 3-16 carbon atoms and which are optionally broken by one or more oxygen atoms, the amino groups being present in a free form or in the form of (the cation portion of) a non-toxic salt, andB. is insoluble in water or other solvents, but capable of swelling in water to gel form, 1 g of the dry product in the form of an HCl salt in the presence of water swelling to at least 5 ml and to at most 50 ml, preferably to at least 5 ml and to at most 25 ml, andC. is in grain form having a particle size substantially within the range of 1 to 1000 .mu., preferably 10 to 800 .mu., andD. has an ion-exchange capacity within the range of 0.2 to 1 milliequivalents chloride ions, preferably 0.3 to 0.9 milliequivalents chloride ions, per 100 mg of dry gel,A method for its preparation and use for lowering the cholesterol content of the blood of mammals and birds.
摘要翻译： 含氨基的药物产品：
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