Methods for assisting recovery of damaged brain and spinal cord and treating various diseases using arrays of x-ray microplanar beams
    1.
    发明授权
    Methods for assisting recovery of damaged brain and spinal cord and treating various diseases using arrays of x-ray microplanar beams 有权
    帮助恢复损伤的脑和脊髓并使用x射线微平面梁阵列治疗各种疾病的方法

    公开(公告)号:US07746979B2

    公开(公告)日:2010-06-29

    申请号:US11884158

    申请日:2006-02-10

    IPC分类号: A61N5/10

    摘要: A method of assisting recovery of an injury site of the central nervous system (CNS) or treating a disease includes providing a therapeutic dose of X-ray radiation to a target volume through an array of parallel microplanar beams. The dose to treat CNS injury temporarily removes regeneration inhibitors from the irradiated site. Substantially unirradiated cells surviving between beams migrate to the in-beam portion and assist recovery. The dose may be staggered in fractions over sessions using angle-variable intersecting microbeam arrays (AVIMA). Additional doses are administered by varying the orientation of the beams. The method is enhanced by injecting stem cells into the injury site. One array or the AVIMA method is applied to ablate selected cells in a target volume associated with disease for palliative or curative effect. Atrial fibrillation is treated by irradiating the atrial wall to destroy myocardial cells while continuously rotating the subject.

    摘要翻译: 辅助恢复中枢神经系统(CNS)的损伤部位或治疗疾病的方法包括通过平行微平面光束阵列向目标体积提供治疗剂量的X射线辐射。 治疗CNS损伤的剂量暂时从照射部位移除再生抑制剂。 在梁之间存活的基本未照射的细胞迁移到入射梁部分并辅助恢复。 剂量可以使用角度可变的相交微束阵列(AVIMA)在会话上以分数交错。 通过改变梁的取向来施加额外的剂量。 通过将干细胞注射到损伤部位来增强该方法。 应用一个阵列或AVIMA方法来消融与疾病相关的目标体内的选择的细胞用于姑息治疗或治疗效果。 通过照射心房壁来破坏心肌细胞,同时持续旋转受试者来治疗房颤。

    Methods for Assisting Recovery of Damaged Brain and Spinal Cord and Treating Various Diseases Using Arrays of X-Ray Microplanar Beams
    2.
    发明申请
    Methods for Assisting Recovery of Damaged Brain and Spinal Cord and Treating Various Diseases Using Arrays of X-Ray Microplanar Beams 有权
    使用X射线微平面光束阵列辅助损伤脑脊髓的恢复和治疗各种疾病的方法

    公开(公告)号:US20080292052A1

    公开(公告)日:2008-11-27

    申请号:US11884158

    申请日:2006-02-10

    IPC分类号: A61N5/10

    摘要: A method of assisting recovery of an injury site of the central nervous system (CNS) or treating a disease includes providing a therapeutic dose of X-ray radiation to a target volume through an array of parallel microplanar beams. The dose to treat CNS injury temporarily removes regeneration inhibitors from the irradiated site. Substantially unirradiated cells surviving between beams migrate to the in-beam portion and assist recovery. The dose may be staggered in fractions over sessions using angle-variable intersecting microbeam arrays (AVIMA). Additional doses are administered by varying the orientation of the beams. The method is enhanced by injecting stem cells into the injury site. One array or the AVIMA method is applied to ablate selected cells in a target volume associated with disease for palliative or curative effect. Atrial fibrillation is treated by irradiating the atrial wall to destroy myocardial cells while continuously rotating the subject.

    摘要翻译: 辅助恢复中枢神经系统(CNS)的损伤部位或治疗疾病的方法包括通过平行微平面光束阵列向目标体积提供治疗剂量的X射线辐射。 治疗CNS损伤的剂量暂时从照射部位移除再生抑制剂。 在梁之间存活的基本未照射的细胞迁移到入射梁部分并辅助恢复。 剂量可以使用角度可变的相交微束阵列(AVIMA)在会话上以分数交错。 通过改变梁的取向来施加额外的剂量。 通过将干细胞注射到损伤部位来增强该方法。 应用一个阵列或AVIMA方法来消融与疾病相关的目标体内的选择的细胞用于姑息治疗或治疗效果。 通过照射心房壁来破坏心肌细胞,同时持续旋转受试者来治疗房颤。