公开(公告)号：US20100222373A1

公开(公告)日：2010-09-02

申请号：US12615935

申请日：2009-11-10

Applicant: Rebecca Jane Booth ,  Peter Anthony Cittern ,  Jeffrey Norman Crabb ,  John Horbury ,  David Way Calvert Jones

Inventor： Rebecca Jane Booth ,  Peter Anthony Cittern ,  Jeffrey Norman Crabb ,  John Horbury ,  David Way Calvert Jones

IPC: A61K31/505 ,  C07D239/42 ,  A61P3/06 ,  A61P9/10

CPC classification number: C07D239/42

Abstract: Two polymorphic forms of bis[(E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl](3R,5S)-3,5-dihydroxyhept-6-enoic acid] calcium salt, processes for making them and their use as HMG Co-A reductase inhibitors are described.

Abstract translation: 双[（E）-7- [4-（4-氟苯基）-6-异丙基-2- [甲基（甲基磺酰基）氨基]嘧啶-5-基]（3R，5S）-3,5-二 二羟基庚-6-烯酸]钙盐，其制备方法及其作为HMG Co-A还原酶抑制剂的用途。