公开(公告)号：US06319190B1

公开(公告)日：2001-11-20

申请号：US09424895

申请日：2000-02-14

Applicant: Werner Schmidt ,  Renate Freudenberger ,  Michael Andrassy ,  Jürgen Ziegler ,  Detlev Behrendt ,  Andre Hess

Inventor： Werner Schmidt ,  Renate Freudenberger ,  Michael Andrassy ,  Jürgen Ziegler ,  Detlev Behrendt ,  Andre Hess

IPC: A61N500

CPC classification number: C25D3/50 ,  A61N5/1002 ,  A61N2005/1019 ,  C25D5/10

Abstract: The invention relates to radioactive ruthenium sources with a dosage rate of at least 1.5 Gy/min at a distance (water) of 2 mm, consisting of an activity carrier and an encapsulation of the carrier made of a material compatible with the human body. A multilayer system made of metals and/or alloys is galvanically applied on the carrier. At least two layers in said system are made of ruthenium 106 and inactive intermediate layers made of other metals or alloys are provided between the radioactive ruthenium layers. The activity carrier is encapsulated with a material compatible with the human body, for instance a metal or a plastic material. Encapsulation can be carried out by filing a capsule and subsequently sealing or galvanically depositing a top layer made, for instance of hard gold.

Abstract translation: 本发明涉及放射性钌源，其距离（水）为2mm的剂量率至少为1.5Gy / min，由活性载体和由与人体相容的材料制成的载体的包封组成。 由金属和/或合金制成的多层系统电镀施加在载体上。 所述系统中的至少两层由钌106制成，并且在放射性钌层之间提供由其它金属或合金制成的非活性中间层。 活性载体用与人体相容的材料（例如金属或塑料材料）包封。 封装可以通过填充胶囊并随后密封或电沉积由例如硬金制成的顶层来进行。