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公开(公告)号:US5986070A
公开(公告)日:1999-11-16
申请号:US918101
申请日:1997-08-27
CPC分类号: C12N15/70 , C07K14/475 , C07K14/48 , C07K14/503 , A61K38/00
摘要: This invention describes processes for producing mature human members of the NGF/BDNF family of neurotrophic proteins that are fully biologically active. In addition, the gene encoding human BDNF and human BDNF are disclosed. A previously-unreported member of the NGF/BDNF family of neurotrophic proteins, NGF-3, has been identified and a portion of the gene encoding for the NGF-3 has been described.
摘要翻译: 本发明描述了用于产生完全生物活性的神经营养蛋白NGF / BDNF家族的成熟人成员的方法。 此外,公开了编码人BDNF和人BDNF的基因。 已经鉴定了NGF / BDNF神经营养蛋白家族NGF-3之前未报道的成员,并且已经描述了编码NGF-3的一部分基因。