公开(公告)号：US07089046B2

公开(公告)日：2006-08-08

申请号：US10187514

申请日：2002-07-02

申请人： Ronald W. Heil, Jr. ,  Gregory R. Ley ,  Dwight Skinner ,  Larry L. Hum

发明人： Ronald W. Heil, Jr. ,  Gregory R. Ley ,  Dwight Skinner ,  Larry L. Hum

IPC分类号： A61B5/04

CPC分类号： A61N1/0573

摘要： A helical element for insertion into tissue comprises a helical element having an insertion end, a protruding end and an open central area within the wire, rods, filaments, cables or the like that form the helix. The helical element has at least its insertion end covered by a cap of a water-soluble or water-dispersible composition. The cap is provided with a surface shape in a cross-section in which surface variations are present in the cross-section which create a surface orientation where a line from the center of the cross-section can intersect the surface, and a line perpendicular to said radius at a point of intersection with said surface forms four quadrants, three of said quadrants containing water-soluble or water-dispersible cap material. There is either a hollow area within the composition within the open central area or the material is more porous than the remaining material. The helical element preferably comprises an electrical lead, such as a positive endocardial lead, with an electrode at the protruding or distal end of the lead.The helical element may comprise any biocompatable material with sufficient structural integrity to provide a secure attachment to tissue in a patient. Where the helical element is also to provide an active (electrically active) function, the composition of the helical element should also be electrically conductive.

摘要翻译： 用于插入组织的螺旋元件包括螺旋元件，其具有插入端，突出端和形成螺旋的线内的开口中心区域，杆，细丝，电缆等。 螺旋元件的至少其插入端被水溶性或水分散性组合物的盖子覆盖。 该盖在横截面中具有表面形状，其中在横截面中存在表面变化，其形成表面取向，其中横截面中心的线可以与表面相交，并且垂直于 在与所述表面的交点处的所述半径形成四个象限，所述象限中的三个包含水溶性或水分散性盖材料。 组合物中的中空区域在开放的中心区域内，或者材料比剩余的材料多孔。 螺旋元件优选地包括电引线，例如正心内膜引线，在引线的突出或远端具有电极。

公开(公告)号：US06473633B1

公开(公告)日：2002-10-29

申请号：US09363477

申请日：1999-07-29

申请人： Ronald W. Heil, Jr. ,  Gregory R. Ley ,  Dwight Skinner ,  Larry L. Hum

发明人： Ronald W. Heil, Jr. ,  Gregory R. Ley ,  Dwight Skinner ,  Larry L. Hum

IPC分类号： A61B5042

CPC分类号： A61N1/0573

摘要： A helical element for insertion into tissue comprises a helical element having an insertion end, a protruding end and an open central area within the wire, rods, filaments, cables or the like that form the helix. The helical element has at least its insertion end covered by a cap of a water-soluble or water-dispersible composition. The cap is provided with a surface shape in a cross-section in which surface variations are present in the cross-section which create a surface orientation where a line from the center of the cross-section can intersect the surface, and a line perpendicular to said radius at a point of intersection with said surface forms four quadrants, three of said quadrants containing water-soluble or water-dispersible cap material. There is either a hollow area within the composition within the open central area or the material is more porous than the remaining material. The helical element preferably comprises an electrical lead, such as a positive endocardial lead, with an electrode at the protruding or distal end of the lead. The helical element may comprise any biocompatable material with sufficient structural integrity to provide a secure attachment to tissue in a patient. Where the helical element is also to provide an active (electrically active) function, the composition of the helical element should also be electrically conductive.

摘要翻译： 用于插入组织的螺旋元件包括螺旋元件，其具有插入端，突出端和形成螺旋的线内的开口中心区域，杆，细丝，电缆等。 螺旋元件的至少其插入端被水溶性或水分散性组合物的盖子覆盖。 盖在横截面中设置有表面形状，其中在横截面中存在表面变化，其产生表面取向，其中横截面中心的线可以与表面相交，并且垂直于 在与所述表面的交点处的所述半径形成四个象限，所述象限中的三个包含水溶性或水分散性盖材料。 组合物中的中空区域在开放的中心区域内，或者材料比剩余的材料多孔。 螺旋元件优选地包括电引线，例如正性心内膜引线，在引线的突出或远端具有电极。螺旋元件可以包括具有足够结构完整性的任何可生物相容的材料，以提供与 患者。 当螺旋元件也提供活性（电活性）功能时，螺旋元件的组成也应当是导电的。

公开(公告)号：US06456888B1

公开(公告)日：2002-09-24

申请号：US09642171

申请日：2000-08-18

申请人： Dwight Skinner ,  Michael P. Brenzel

发明人： Dwight Skinner ,  Michael P. Brenzel

IPC分类号： A61N105

CPC分类号： A61N1/05

摘要： A method for securing a coil or cable conductor to an electric element including an implantable electric element having a longitudinal edge electrically coupled to a coil or cable conductor. The coil or cable having filars with ends configured to contact the longitudinal edge of the electric element. The ends secured to the longitudinal edge by welding, soldering or an electrically conductive adhesive.

摘要翻译： 一种用于将线圈或电缆导体固定到电气元件的方法，所述电气元件包括具有电耦合到线圈或电缆导体的纵向边缘的可植入电气元件。 线圈或电缆具有丝线，端部被配置为接触电气元件的纵向边缘。 端部通过焊接，焊接或导电粘合剂固定到纵向边缘。

公开(公告)号：US06374142B1

公开(公告)日：2002-04-16

申请号：US09510422

申请日：2000-02-22

申请人： Dwight Skinner ,  Chris Knapp

发明人： Dwight Skinner ,  Chris Knapp

IPC分类号： A61N104

CPC分类号： A61N1/056

摘要： A joint for a cardiac stimulation lead is disclosed that connects a lead body and a coil conductor with an isodiametric junction. The lead body includes a counterbore disposed at its distal end. The lead body's counterbore securably receives the inner insulator of the coil conductor. Alternatively, the coil conductor includes a counterbore disposed at its proximal end. The coil conductor's counterbore securably receives the distal end of the lead body.

摘要翻译： 公开了一种用于心脏刺激引线的接头，其将引线体和线圈导体与等参点连接。 引线体包括设置在其远端处的沉孔。 引线体的沉孔牢固地容纳线圈导体的内绝缘体。 或者，线圈导体包括设置在其近端的沉孔。 线圈导体的沉孔牢固地容纳引线体的远端。

公开(公告)号：US06263250B1

公开(公告)日：2001-07-17

申请号：US09352557

申请日：1999-07-13

申请人： Dwight Skinner

发明人： Dwight Skinner

IPC分类号： A61N105

CPC分类号： A61N1/056 ,  Y10T29/49117

摘要： A lead assembly having a ring electrode is adapted for implant and for connection to a system for monitoring or stimulating cardiac activity. The lead assembly includes a first porous member disposed around the ring electrode at the distal end of the lead assembly, which can be used as a sensing or pacing interface with the cardiac tissue. In addition, a second porous member is disposed over the first porous member and is electrically coupled with the ring electrode.

摘要翻译： 具有环形电极的引线组件适于植入和连接到用于监测或刺激心脏活动的系统。 引线组件包括设置在引线组件的远端处的环形电极周围的第一多孔构件，其可以用作与心脏组织的感测或起搏界面。 此外，第二多孔构件设置在第一多孔构件上并与环电极电耦合。

公开(公告)号：US06477428B1

公开(公告)日：2002-11-05

申请号：US09514811

申请日：2000-02-28

申请人： Dwight Skinner ,  Stuart R. Chastain ,  Mohan Krishnan ,  Chris Zerby

发明人： Dwight Skinner ,  Stuart R. Chastain ,  Mohan Krishnan ,  Chris Zerby

IPC分类号： A61N105

CPC分类号： A61N1/056

摘要： A lead has a flexible lead body which extends from a proximal end to a distal end. The lead body has a conductor coupled with an electrode. At least a portion of the flexible lead body includes a polymer of vinylidene fluoride, or a polymer of vinylidene fluoride and silicone rubber. The polymer of vinylidene fluoride includes, but is not limited to, a homopolymer, a copolymer, or a terpolymer.

摘要翻译： 导线具有从近端延伸到远端的柔性引线体。 引线体具有与电极耦合的导体。 柔性引线体的至少一部分包括偏二氟乙烯的聚合物，或偏二氟乙烯和硅橡胶的聚合物。 偏二氟乙烯的聚合物包括但不限于均聚物，共聚物或三元共聚物。

公开(公告)号：US06516232B2

公开(公告)日：2003-02-04

申请号：US09907540

申请日：2001-07-17

申请人： Dwight Skinner

发明人： Dwight Skinner

IPC分类号： A61N105

CPC分类号： A61N1/056 ,  Y10T29/49117

摘要： A lead assembly having a ring electrode is adapted for implant and for connection to a system for monitoring or stimulating cardiac activity. The lead assembly includes a first porous member disposed around the ring electrode at the distal end of the lead assembly, which can be used as a sensing or pacing interface with the cardiac tissue. In addition, a second porous member is disposed over the first porous member and is electrically coupled with the ring electrode.