Parathormone fragments, their preparation and medicaments containing
these
    1.
    发明授权
    Parathormone fragments, their preparation and medicaments containing these 失效
    parathormone片段,它们的制备和含有这些的药物

    公开(公告)号:US5783558A

    公开(公告)日:1998-07-21

    申请号:US256363

    申请日:1994-07-20

    CPC分类号: C07K14/635 A61K38/00

    摘要: The invention concerns parathormone (PTH) fragments including the amino acid range of the natural parathormone of +3 to +35 and their physiologically compatible derivatives, a process for the preparation of the fragments according to the solid phase and liquid phase synthesis from partly blocked amino acids contained in the fragments which are coupled with one another in the sequence which corresponds to the amino acid sequence in the fragments to be prepared and medicaments containing at least one of the fragments, especially with calcium-regulating action in the body.

    摘要翻译: PCT No.PCT / EP93 / 00259 Sec。 371日期:1994年7月20日 102(e)日期1994年7月20日PCT提交1993年2月4日PCT公布。 公开号WO93 / 15109 日期:1993年8月5日本发明涉及包含+3至+35的天然parathormone的氨基酸范围及其生理上相容的衍生物的parathormone(PTH)片段,根据固相和液相制备片段的方法 从与待制备的片段中的氨基酸序列相对应的序列中彼此偶联的片段中包含的部分封闭的氨基酸合成,以及含有至少一个片段的药物,特别是在 身体。