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33 条记录 (耗时 0.022 秒)

    Prosthesis for hip replacement with polyethylene head and anti-rotational intra-prosthetic assembly
    1.
    发明授权
    Prosthesis for hip replacement with polyethylene head and anti-rotational intra-prosthetic assembly 有权

    公开(公告)号：US11638647B2

    公开(公告)日：2023-05-02

    申请号：US16977712

    申请日：2018-03-09

    申请人： Rafael Eduardo Perez Nunez

    发明人： Rafael Eduardo Perez Nunez

    IPC分类号： A61F2/32 ,  A61F2/36 ,  A61F2/34 ,  C08L23/06 ,  A61F2/30

    摘要： This invention corresponds to a prosthesis for total or hip resurfacing replacement, which comprises a prosthetic femoral head made of highly cross-linked polyethylene, with a diameter ranging from 38 mm to 64 mm, to articulate with a cup or acetabular component made of metal. When the invention applies to total hip replacement, the polyethylene head includes a metal core, which contains inside the female counterpart (14) to mate with the male counterpart (13) of a Morse taper, located at the upper end of the femoral component. The use of this type of head for total hip replacement, articulated with an ultra-polished acetabular cup, reduces the risk of dislocation, transmits less angular and torque forces to the Morse taper than large metal heads, and avoids the problems related to the metal-metal bearing or with the use of large metal heads with thin polyethylene. When the invention relates to hip resurfacing replacement, the highly cross-linked polyethylene femoral head has a lower polyethylene extension or stem with or without internal metal reinforcement (151) or a metal stem integrated into a metal-back (152). Using these types of heads for hip resurfacing replacement heads eliminates the problems associated with metal-on-metal resurfacing replacements.

    Force location apparatus, systems, and methods
    2.
    发明授权
    Force location apparatus, systems, and methods 有权

    公开(公告)号：US10371564B2

    公开(公告)日：2019-08-06

    申请号：US14699438

    申请日：2015-04-29

    申请人： Jorge Eduardo Perez Jacome

    发明人： Jorge Eduardo Perez Jacome

    IPC分类号： G06Q20/00 ,  G01G19/414 ,  G01M1/12 ,  G01G19/415

    摘要： Various embodiments of apparatus, systems, and methods operate to receive measurements corresponding to a plurality of forces sensed substantially simultaneously at a substantially planar, weight-bearing measurement surface. Additional activity includes determining a location on the surface, based on a combination of the measurements, of an equivalent force that corresponds to the combination of the measurements. Additional apparatus, systems, and methods are disclosed.

    Cysteinyl compounds, compositions and methods of use
    4.
    发明申请
    Cysteinyl compounds, compositions and methods of use 有权
    半胱氨酰化合物，组合物和使用方法

    公开(公告)号：US20120328540A1

    公开(公告)日：2012-12-27

    申请号：US13566839

    申请日：2012-08-03

    申请人： Jeffry B. Stock ,  Maxwell Stock ,  Keshava Rapole ,  Seung-Yub Lee ,  Michael Voronkov ,  Eduardo Perez ,  Joel Gordon ,  Shuyi Chen

    发明人： Jeffry B. Stock ,  Maxwell Stock ,  Keshava Rapole ,  Seung-Yub Lee ,  Michael Voronkov ,  Eduardo Perez ,  Joel Gordon ,  Shuyi Chen

    IPC分类号： A61K31/197 ,  A61P17/00 ,  A61P17/14 ,  A61P17/12 ,  A61P29/00 ,  A61P17/08 ,  A61P17/06 ,  A61P37/08 ,  A61P19/04 ,  A61P19/02 ,  A61P31/00 ,  A61P17/10 ,  A61P31/04 ,  A61P17/02 ,  A61Q17/04 ,  C07C321/08

    CPC分类号： A61K31/197 ,  C07C323/59

    摘要： Among other things, the present invention provides novel compounds capable of effectively inhibiting inflammatory responses that are mediated by G-proteins or GPCRs in neutrophils, macrophages and platelets. In particular, the compounds of the present invention act as inhibitors of edema, inhibitors of erythema and inhibitors of MPO (myeloperoxidase), pharmaceutical compositions containing the same compounds and the use thereof for the treatment of diseases that may benefit from edema, erythema and MPO inhibition, such as inflammation (acute or chronic), asthma, autoimmune diseases, and chronic obstructive pulmonary disease (COPD) (e.g., emphysema, chronic bronchitis and small airways disease, etc.), inflammatory responses of the immune system, skin diseases (e.g., reducing acute skin irritation for patients suffering from rosacea, atopic dermatitis, seborrheic dermatitis, psoriasis), irritable bowel syndrome (e.g., Chron's disease and ulcerative colitis, etc.), and central nervous system disorders (e.g., Parkinson's disease).

    摘要翻译： 除此之外，本发明提供能够有效抑制嗜中性粒细胞，巨噬细胞和血小板中G蛋白或GPCR介导的炎症反应的新型化合物。 特别地，本发明的化合物作为水肿抑制剂，红斑抑制剂和MPO抑制剂（髓过氧化物酶），含有相同化合物的药物组合物及其用于治疗可能受益于水肿，红斑和MPO的疾病的用途 抑制，如炎症（急性或慢性），哮喘，自身免疫性疾病和慢性阻塞性肺疾病（COPD）（例如肺气肿，慢性支气管炎和小气道疾病等），免疫系统的炎症反应，皮肤疾病 例如，对于患有酒渣鼻，特应性皮炎，脂溢性皮炎，牛皮癣的患者，肠易激综合征（例如，Chron氏病和溃疡性结肠炎等）以及中枢神经系统疾病（例如帕金森病）的患者减少急性皮肤刺激。

    Estimating a signal based on samples derived from dot products and random projections
    5.
    发明授权
    Estimating a signal based on samples derived from dot products and random projections 有权
    基于从点积和随机投影得到的样本估计信号

    公开(公告)号：US08239436B2

    公开(公告)日：2012-08-07

    申请号：US12236786

    申请日：2008-09-24

    申请人： Eduardo Perez

    发明人： Eduardo Perez

    IPC分类号： G06F17/14 ,  G06F7/52

    CPC分类号： G06F17/17

    摘要： A system and method for estimating a signal based on a stream of randomly generated samples. The method includes: (a) receiving a sample; (b) generating a sampling vector; (c) multiplying the sample and the sampling vector to obtain a current back projection; (d) computing a first intermediate vector that represents an average of the current back projection and previous back projections; (e) transforming the first intermediate vector to determine a second intermediate vector; (f) identifying locations where the second intermediate vector attains its k largest values; (g) computing an estimate for the transformation of the signal by solving a system of equations based on the identified locations, the received sample value, previously received sample values, the sampling vector and previously generated sampling vectors; (h) inverse transforming the transformation estimate to determine an estimate of the signal; and (i) storing the signal estimate.

    摘要翻译： 一种用于基于随机生成的样本流来估计信号的系统和方法。 该方法包括：（a）接收样品; （b）产生采样矢量; （c）乘以样本和采样矢量以获得电流反投影; （d）计算表示当前反投影和先前后投影的平均值的第一中间向量; （e）转化第一中间载体以确定第二中间载体; （f）识别第二中间向量达到其k个最大值的位置; （g）通过基于所识别的位置，所接收的采样值，先前接收的采样值，采样矢量和先前产生的采样矢量求解方程组，来计算信号变换的估计; （h）逆变换所述变换估计以确定所述信号的估计; 和（i）存储信号估计。

    Detection of textural defects using a one class support vector machine
    6.
    发明授权
    Detection of textural defects using a one class support vector machine 有权
    使用一类支持向量机检测纹理缺陷

    公开(公告)号：US08457414B2

    公开(公告)日：2013-06-04

    申请号：US12632389

    申请日：2009-12-07

    申请人： Sina Jahanbin ,  Alan C. Bovik ,  Eduardo Perez ,  Dinesh Nair

    发明人： Sina Jahanbin ,  Alan C. Bovik ,  Eduardo Perez ,  Dinesh Nair

    IPC分类号： G06T9/62

    CPC分类号： G06K9/52 ,  G06T7/0004 ,  G06T7/45 ,  G06T2207/20016 ,  G06T2207/20064

    摘要： Method for detecting textural defects in an image. The image, which may have an irregular visual texture, may be received. The image may be decomposed into a plurality of subbands. The image may be portioned into a plurality of partitions. A plurality of grey-level co-occurrence matrices (GLCMs) may be determined for each partition. A plurality of second-order statistical attributes may be extracted for each GLCM. A feature vector may be constructed for each partition, where the feature vector includes the second order statistical attributes for each GLCM for the partition. Each partition may be classified based on the feature vector for the respective partition. Classification of the partitions may utilize a one-class support vector machine, and may determine if a defect is present in the image.

    摘要翻译： 用于检测图像中的纹理缺陷的方法。 可以接收可能具有不规则视觉纹理的图像。 图像可以被分解成多个子带。 图像可以分成多个分区。 可以为每个分区确定多个灰度共生矩阵（GLCM）。 可以为每个GLCM提取多个二阶统计属性。 可以为每个分区构造特征向量，其中特征向量包括用于分区的每个GLCM的二阶统计属性。 可以基于相应分区的特征向量对每个分区进行分类。 分区的分类可以利用一类支持向量机，并且可以确定图像中是否存在缺陷。

    Detection of Textural Defects Using a One Class Support Vector Machine
    8.
    发明申请
    Detection of Textural Defects Using a One Class Support Vector Machine 有权
    使用一类支持向量机检测纹理缺陷

    公开(公告)号：US20110026804A1

    公开(公告)日：2011-02-03

    申请号：US12632389

    申请日：2009-12-07

    申请人： Sina Jahanbin ,  Alan C. Bovik ,  Eduardo Perez ,  Dinesh Nair

    发明人： Sina Jahanbin ,  Alan C. Bovik ,  Eduardo Perez ,  Dinesh Nair

    IPC分类号： G06K9/00

    CPC分类号： G06K9/52 ,  G06T7/0004 ,  G06T7/45 ,  G06T2207/20016 ,  G06T2207/20064

    摘要： Method for detecting textural defects in an image. The image, which may have an irregular visual texture, may be received. The image may be decomposed into a plurality of subbands. The image may be portioned into a plurality of partitions. A plurality of grey-level co-occurrence matrices (GLCMs) may be determined for each partition. A plurality of second-order statistical attributes may be extracted for each GLCM. A feature vector may be constructed for each partition, where the feature vector includes the second order statistical attributes for each GLCM for the partition. Each partition may be classified based on the feature vector for the respective partition. Classification of the partitions may utilize a one-class support vector machine, and may determine if a defect is present in the image.

    摘要翻译： 用于检测图像中的纹理缺陷的方法。 可以接收可能具有不规则视觉纹理的图像。 图像可以被分解成多个子带。 图像可以分成多个分区。 可以为每个分区确定多个灰度共生矩阵（GLCM）。 可以为每个GLCM提取多个二阶统计属性。 可以为每个分区构造特征向量，其中特征向量包括用于分区的每个GLCM的二阶统计属性。 可以基于相应分区的特征向量对每个分区进行分类。 分区的分类可以利用一类支持向量机，并且可以确定图像中是否存在缺陷。

    Shunt tube connector lock
    10.
    发明授权
    Shunt tube connector lock 有权
    分流管连接器锁

    公开(公告)号：US07497267B2

    公开(公告)日：2009-03-03

    申请号：US11154180

    申请日：2005-06-16

    申请人： John Richard Setterberg, Jr. ,  Alejandro Eduardo Perez

    发明人： John Richard Setterberg, Jr. ,  Alejandro Eduardo Perez

    IPC分类号： E21B43/10 ,  E21B43/00

    CPC分类号： E21B43/04 ,  E21B17/02

    摘要： A locking mechanism for securing a jumper tube to a shunt tube in a well screen assembly for use in gravel packing features a jumper tube having a telescoping connector that extends to engage the shunt tube and a locking mechanism that extends the connector the proper distance and then locks the connector into place by engaging lugs that are connected to the jumper tube. An apparatus and method for securing a connector tube to a well screen assembly features a receiver that is attached to the well screen assembly and is configured to receive a connector tube and secure the connector tube into place with screws. The receiver can be mounted to the well screen assembly via the shunt tube, a top/middle-bottom ring assembly, directly to the base pipe.

    摘要翻译： 用于将跳线管固定到用于砾石填充的井眼组件中的分流管的锁定机构具有跨接管，其具有延伸以接合分流管的伸缩连接器和将连接器延伸适当距离的锁定机构 通过接合连接到跳线管的凸耳将连接器锁定到位。 用于将连接器管固定到井筛组件的装置和方法具有附接到井筛组件的接收器，并且构造成接收连接器管并且用螺钉将连接器管固定就位。 接收器可以通过分流管，顶/中 - 底环组件直接安装到井筛组件上，直到底管。