Mitotic kinesin inhibitors
    1.
    发明申请
    Mitotic kinesin inhibitors 失效
    有丝分裂驱动蛋白抑制剂

    公开(公告)号:US20060052611A1

    公开(公告)日:2006-03-09

    申请号:US10539512

    申请日:2003-12-16

    IPC分类号: C07D401/02 C07D211/70

    CPC分类号: C07D401/04 C07D211/70

    摘要: The present invention relates to tetrahydropyridine compounds that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals

    摘要翻译: 本发明涉及可用于治疗细胞增殖性疾病,用于治疗与KSP驱动蛋白活性相关的病症和用于抑制KSP驱动蛋白的四氢吡啶化合物。 本发明还涉及包含这些化合物的组合物,以及使用它们治疗哺乳动物癌症的方法