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公开(公告)号：US6120497A
公开(公告)日：2000-09-19
申请号：US153052
申请日：1998-09-15
CPC分类号： A61B18/203 , A61B2017/00761 , A61B2018/00023 , A61B2018/00029 , A61B2018/00452 , A61B2018/0047 , A61N2005/067
摘要： A method for treating wrinkles in skin involves the use of a beam of pulsed, scanned or gated continuous wave laser or incoherent radiation. The method comprises generating a beam of radiation, directing the beam of radiation to a targeted dermal region between 100 microns and 1.2 millimeters below a wrinkle in the skin, and thermally injuring collagen in the targeted dermal region. The beam of radiation has a wavelength of between 1.3 and 1.8 microns. The method may include cooling an area of the skin above the targeted dermal region while partially denaturing the collagen in the targeted dermal region. The method may also include cooling an area of the skin above the targeted dermal region prior to thermally injuring collagen in the targeted dermal region.
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公开(公告)号：US5810801A
公开(公告)日：1998-09-22
申请号：US794876
申请日：1997-02-05
CPC分类号： A61B18/203 , A61B2017/00761 , A61B2018/00023 , A61B2018/00029 , A61B2018/00452 , A61B2018/0047 , A61N2005/067
摘要： A method for treating wrinkles in skin involves the use of a beam of puls scanned or gated continuous wave laser or incoherent radiation. The method comprises generating a beam of radiation, directing the beam of radiation to a targeted dermal region between 100 microns and 1.2 millimeters below a wrinkle in the skin, and thermally injuring collagen in the targeted dermal region. The beam of radiation has a wavelength of between 1.3 and 1.8 microns. The method may include cooling an area of the skin above the targeted dermal region while partially denaturing the collagen in the targeted dermal region. The method may also include cooling an area of the skin above the targeted dermal region prior to thermally injuring collagen in the targeted dermal region.
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公开(公告)号：US06659999B1
公开(公告)日：2003-12-09
申请号：US09587156
申请日：2000-06-05
IPC分类号： A61B1818
CPC分类号： A61B18/203 , A61B2017/00761 , A61B2018/00023 , A61B2018/00029 , A61B2018/00452 , A61B2018/0047 , A61N2005/067
摘要： A method for treating wrinkles in skin involves the use of a beam of pulsed, scanned or gated continuous wave laser or incoherent radiation. The method comprises generating a beam of radiation, directing the beam of radiation to a targeted dermal region between 100 microns and 1.2 millimeters below a wrinkle in the skin, and thermally injuring collagen in the targeted dermal region. The beam of radiation has a wavelength of between 1.3 and 1.8 microns. The method may include cooling an area of the skin above the targeted dermal region while partially denaturing the collagen in the targeted dermal region. The method may also include cooling an area of the skin above the targeted dermal region prior to thermally injuring collagen in the targeted dermal region.
摘要翻译： 用于治疗皮肤皱纹的方法涉及使用脉冲，扫描或门控的连续波激光束或非相干辐射束。 该方法包括产生辐射束，将辐射束引导到皮肤皱纹以下100微米至1.2毫米之间的目标皮肤区域，并且热损伤目标皮肤区域中的胶原蛋白。 辐射束的波长在1.3和1.8微米之间。 该方法可以包括冷却目标皮肤区域上方的皮肤区域，同时部分地使目标皮肤区域中的胶原变性。 该方法还可以包括在热损伤目标皮肤区域中的胶原之前冷却目标皮肤区域之上的皮肤区域。
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4.发明授权公开(公告)号：US07891362B2
公开(公告)日：2011-02-22
申请号：US11645222
申请日：2006-12-22
IPC分类号： A61B19/00
CPC分类号： A61B18/203 , A61B2018/00005 , A61B2018/00452 , A61B2018/0047
摘要： A beam of radiation can be provided to treat a dermatological condition in a target region of skin. The beam of radiation can have a wavelength between about 700 nm and about 800 nm, a fluence greater than about 50 J/cm2, and a pulse duration between about 10 msec and about 300 msec. The beam of radiation is delivered to the target region of skin to affect (i) at least one pigmentary abnormality disposed in an epidermal region of the target region and (ii) at least one vascular abnormality disposed in a dermal region of the target region. A surface of the epidermal region of the target region of skin can be cooled to prevent substantial unwanted injury to at least a portion of the epidermal region.
摘要翻译： 可以提供辐射束以治疗皮肤的目标区域中的皮肤病学状况。 辐射束可以具有在约700nm和约800nm之间的波长，大于约50J / cm 2的通量，以及约10msec至约300msec之间的脉冲持续时间。 辐射束被传送到皮肤的目标区域，以影响（i）设置在目标区域的表皮区域中的至少一种色素异常和（ii）设置在目标区域的皮肤区域中的至少一种血管异常。 可以冷却皮肤目标区域的表皮区域的表面，以防止对表皮区域的至少一部分造成实质上的不必要的损伤。
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