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公开(公告)号：US11172924B2
公开(公告)日：2021-11-16
申请号：US16355373
申请日：2019-03-15
发明人： Derek Dee Deville , Kevin W. Smith , Michael Walter Kirk , Carlos Rivera , George Nunez , Thomas O. Bales, Jr. , Korey Kline , Matthew A. Palmer , M. Sean McBrayer , Richard George Cartledge , Max Pierre Mendez , Kevin K. Dang , Bryan A. Janish , Manouchehr A. Miraki
摘要： A multiple-firing clip device includes a hollow shaft defining a lateral opening communicating with an environment and a distal shaft portion between the lateral opening and a distal end opening. A shuttle longitudinally moves on the shaft and comprises a shuttle body defining a lumen surrounding the shaft, a snare, and a snare-extender slide defining a snare track to form a snare travel path in which the snare is disposed from the body and through the track and a portion of the body. The slide moves along a given extent defining a slide distance and a distal end and movement of the slide to the distal end shortens the snare travel path to extend the snare portion through the lateral opening, through the distal shaft portion, and distally out from a distal side of the body longer than the given extent to secure a suture with the snare.
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公开(公告)号：US11033389B2
公开(公告)日：2021-06-15
申请号：US16522384
申请日：2019-07-25
发明人： Jan Otto Solem
摘要： A method for replacing a native heart valve in need thereof comprises delivering to the native heart valve an apparatus comprising a valve member, a connecting member, and an anchor member suitable for anchoring the apparatus. The valve member reversibly moves between an open position and a closed position to augment or replace the function of the native valve leaflets, thereby reducing valve regurgitation. Some embodiments include a stent that is positioned in the native heart valve with the valve member disposed therein.
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公开(公告)号：US10786355B2
公开(公告)日：2020-09-29
申请号：US15866338
申请日：2018-01-09
发明人： Avraham Zakai , David Mishaly , Dan Rottenberg , David Alon
摘要： A method of treating a mitral valve without open-heart surgery is disclosed. An expandable prosthesis comprises an anchoring portion and an occluding member coupled to the anchoring portion. The prosthesis is loaded into a distal end of a delivery catheter and advanced through a femoral vein and through a pre-made puncture in an atrial septum. The occluding member is then positioned in the mitral valve and the anchoring portion is positioned in the left atrium for maintaining the occluding member between the leaflets of the mitral valve. After deployment, the occluding member prevents blood from flowing from the left ventricle to the left atrium during systole.
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公开(公告)号：US20200046484A1
公开(公告)日：2020-02-13
申请号：US16590230
申请日：2019-10-01
发明人： Judith T. Carpenter , Jeffrey P. Carpenter , David A. Rezac , Jeffrey C. Cerier , Richard C. Fortier , Timothy W. Robinson
IPC分类号： A61F2/01
摘要： There is disclosed a porous emboli deflector for preventing cerebral emboli while maintaining cerebral blood flow during an endovascular or open surgical procedure. The device prevents the entrance of emboli of a size able to cause stroke (such as greater than 100 microns) from entering either the right or left common carotid arteries, and/or the right or left vertebral arteries by deflecting emboli downstream of these vessels. The device can be placed prior to any manipulation of the heart or aorta allowing maximal protection of the brain during the index procedure. The deflector has a low profile within the aorta which allows sheaths, catheters, or wires used in the index procedure to pass. Also disclosed are methods for insertion and removal of the deflector.
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公开(公告)号：US20240268945A1
公开(公告)日：2024-08-15
申请号：US18643899
申请日：2024-04-23
发明人： Judith T. Carpenter , Jeffrey P. Carpenter , David A. Rezac , Jeffrey C. Cerier , Richard C. Fortier , Timothy W. Robinson
IPC分类号： A61F2/01
CPC分类号： A61F2/013 , A61F2/011 , A61F2002/016 , A61F2002/018 , A61F2230/0006 , A61F2230/0008 , A61F2230/0019 , A61F2230/0021 , A61F2230/005 , A61F2230/008 , A61F2230/0093 , A61F2230/0095
摘要： There is disclosed a porous emboli deflector for preventing cerebral emboli while maintaining cerebral blood flow during an endovascular or open surgical procedure. The device prevents the entrance of emboli of a size able to cause stroke (such as greater than 100 microns) from entering either the right or left common carotid arteries, and/or the right or left vertebral arteries by deflecting emboli downstream of these vessels. The device can be placed prior to any manipulation of the heart or aorta allowing maximal protection of the brain during the index procedure. The deflector has a low profile within the aorta which allows sheaths, catheters, or wires used in the index procedure to pass. Also disclosed are methods for insertion and removal of the deflector.
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公开(公告)号：US20190175337A1
公开(公告)日：2019-06-13
申请号：US16280342
申请日：2019-02-20
发明人： Jan Otto Solem , David Alon
摘要： A method of deploying a blood-flow controlling device is described for treating a native mitral or tricuspid valve. The blood-flow controlling device includes a blood-flow blocking portion that is slidable over an elongate body portion. The blood-flow blocking portion is preferably an elongate structure fillable with blood having a portion adapted for placement between leaflets of the native valve. An anchor is located on a distal end of the elongate body portion for engagement with heart tissue adjacent a heart apex. An anchor delivery catheter is advanced through the native valve and into an adjacent ventricle. The anchor is then expelled from the anchor delivery catheter into ventricular tissue. The blood-flow blocking portion is then slid along the elongate body portion and positioned between the native leaflets. A locking catheter is then slid along the elongate body portion for locking the blood-flow blocking portion to the elongate body portion.
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公开(公告)号：US10016193B2
公开(公告)日：2018-07-10
申请号：US14543240
申请日：2014-11-17
发明人： Kevin W. Smith , Max Pierre Mendez , Matthew A. Palmer , M. Sean McBrayer , Thomas O. Bales, Jr. , Derek Dee Deville , Richard Cartledge , Korey Kline , Carlos Rivera , George Nunez
CPC分类号： A61B17/0469 , A61B17/0401 , A61B17/0467 , A61B17/0483 , A61B17/0485 , A61B17/0487 , A61B2017/00398 , A61B2017/0053 , A61B2017/00907 , A61B2017/0409 , A61B2017/0414 , A61B2017/0438 , A61B2017/0453 , A61B2017/0454 , A61B2017/0474 , A61B2017/0475 , A61B2017/0488 , A61B2017/0496 , A61B2090/309
摘要： A multiple-firing crimp device comprises crimps, a shaft, a crimp movement assembly, and a snare. Each crimp has an internal hollow. The shaft has a distal crimping location, an exterior surface, and an interior with the clips stacked therein, the crimps moving therein along a longitudinal axis. The shaft defines a lateral opening proximal to the crimping location and communicates the interior to the environment outside the exterior surface. The crimp movement assembly within the shaft delivers the first crimp to the distal crimping location by moving the first crimp longitudinally from a first proximal position into the distal crimping location and returning to a second proximal position without the first crimp. The snare pulls at least one cord from distal of the first crimp through the first crimp and through a portion of the shaft and out the side of the shaft through the lateral opening.
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公开(公告)号：US20180125645A1
公开(公告)日：2018-05-10
申请号：US15866338
申请日：2018-01-09
发明人： Avraham Zakai , David Mishaly , Dan Rottenberg , David Alon
摘要： A method of treating a mitral valve without open-heart surgery is disclosed. An expandable prosthesis comprises an anchoring portion and an occluding member coupled to the anchoring portion. The prosthesis is loaded into a distal end of a delivery catheter and advanced through a femoral vein and through a pre-made puncture in an atrial septum. The occluding member is then positioned in the mitral valve and the anchoring portion is positioned in the left atrium for maintaining the occluding member between the leaflets of the mitral valve. After deployment, the occluding member prevents blood from flowing from the left ventricle to the left atrium during systole.
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公开(公告)号：US20180078362A1
公开(公告)日：2018-03-22
申请号：US15823445
申请日：2017-11-27
发明人： Jan Otto Solem , David Alon
CPC分类号： A61F2/246 , A61B17/0401 , A61B2017/00243 , A61B2017/0437 , A61B2017/0445 , A61B2017/0453 , A61F2/2466 , A61F2220/0016 , A61F2230/0093 , A61F2240/002
摘要： The invention is a method for reducing regurgitation through a mitral valve. The device and method is directed to an anchor portion for engagement with the heart wall and an expandable valve portion configured for deployment between the mitral valve leaflets. The valve portion is expandable for preventing regurgitation through the mitral valve while allowing blood to circulate through the heart. The expandable valve portion may include apertures for reducing the stagnation of blood. In a preferred configuration, the device is preferably configured to be delivered in two-stages wherein an anchor portion is first delivered and the valve structure is then coupled to the anchor portion. In yet another embodiment, the present invention provides a method of forming an anchor portion wherein a disposable jig is used to mold the anchor portion into a three-dimensional shape for conforming to a heart chamber.
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公开(公告)号：US20160324641A1
公开(公告)日：2016-11-10
申请号：US15214362
申请日：2016-07-19
发明人： Jan Otto Solem
IPC分类号： A61F2/24
CPC分类号： A61F2/2442 , A61B2017/0412 , A61F2/2403 , A61F2/2412 , A61F2/2418 , A61F2/2427 , A61F2/2457 , A61F2/246 , A61F2/2466 , A61F2210/0014 , A61F2220/0008 , A61F2220/0016 , A61F2230/0054 , A61F2310/00017 , A61F2310/00023
摘要： An apparatus for treating a heart valve in need thereof comprises a valve member, a connecting member, and an anchor member suitable for anchoring the apparatus. The valve member reversibly moves between an open position and a closed position to augment or replace the function of the native valve leaflets, thereby reducing valve regurgitation. Some embodiments include a stent that is positioned in the native heart valve with the valve member disposed therein.
摘要翻译： 用于治疗有需要的心脏瓣膜的装置包括阀构件，连接构件和适于锚定装置的锚定构件。 阀构件在打开位置和关闭位置之间可逆地移动以增加或替换本机瓣叶的功能，从而减少瓣膜反流。 一些实施例包括定位在天然心脏瓣膜中的支架，其中阀构件设置在其中。
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