-
1.Chemically Modified Viral Capsids as Targeted Delivery Vectors for Diagnostic and Therapeutic Agents 审中-公开
标题翻译: 化学修饰的病毒衣壳作为诊断和治疗剂的靶向递送载体公开(公告)号:US20110104051A1
公开(公告)日:2011-05-05
申请号:US12294743
申请日:2007-03-27
申请人: Matthew B. Francis , Jacob M. Hooker , Ernest W. Kovacs , Dante W. Romanini , Patrick G. Holder , Katherine E. Berry
发明人: Matthew B. Francis , Jacob M. Hooker , Ernest W. Kovacs , Dante W. Romanini , Patrick G. Holder , Katherine E. Berry
CPC分类号: A61K9/5184 , A61K47/60 , A61K47/6901 , A61K49/0002 , A61K49/1896 , A61K51/1203
摘要: The present invention provides a novel means of delivering imaging agents and/or therapeutic agents to specific cellular sites in an animal involving the use of a viral capsid that is chemically modified on it exterior and/or interior surfaces.
摘要翻译: 本发明提供了一种将成像剂和/或治疗剂递送到动物中的特定细胞部位的新方法,涉及使用在其外表面和/或内表面上化学改性的病毒衣壳。
-
2.(Pyrimidinyl) (phenyl) substituted fused heteroaryl p38 inhibiting and PKG kinase inhibiting compounds 失效
标题翻译: (嘧啶基)(苯基)取代的稠合杂芳基p38抑制和PKG激酶抑制化合物公开(公告)号:US07196095B2
公开(公告)日:2007-03-27
申请号:US10477367
申请日:2002-06-21
申请人: Tesfaye Biftu , Richard Beresis , Richard Berger , Steven L. Colletti , James B. Doherty , Dennis D. Feng , Gui-Bai Liang , Dennis M. Schmatz , Xiaoxia Qian , David A. Claremon , Nigel J. Liverton , Charles J. McIntyre , Ernest W. Kovacs
发明人: Tesfaye Biftu , Richard Beresis , Richard Berger , Steven L. Colletti , James B. Doherty , Dennis D. Feng , Gui-Bai Liang , Dennis M. Schmatz , Xiaoxia Qian , David A. Claremon , Nigel J. Liverton , Charles J. McIntyre , Ernest W. Kovacs
IPC分类号: C07D403/04 , C07D403/14 , C07D417/04 , C07D417/14 , A61K31/506 , A61P19/02
CPC分类号: C07D403/04 , A23K20/10 , A23K20/111 , A61K31/429 , A61K31/4355 , A61K31/506 , A61K31/519 , A61K31/53 , A61K45/06 , C07D453/02 , C07D471/04 , C07D471/08 , C07D487/04 , C07D487/14 , C07D513/04 , A61K2300/00
摘要: Compounds of formula (I) and pharmaceutically acceptable salts thereof are useful in the treatment of cytokine mediated diseases such as arthritis and in the treatment and/or prevention of protozoal diseases such as coccidiosis
摘要翻译: 式(I)化合物及其药学上可接受的盐可用于治疗细胞因子介导的疾病如关节炎和治疗和/或预防原虫感染疾病如球虫病
-