公开(公告)号：US20100160768A1

公开(公告)日：2010-06-24

申请号：US12344169

申请日：2008-12-24

申请人： Nassir F. Marrouche ,  Rob Macleod ,  Eugene Kholmovski ,  Christopher McGann ,  Joshua Blauer ,  Troy Badger ,  Robert Sillman Oakes ,  Nathan Burgon

发明人： Nassir F. Marrouche ,  Rob Macleod ,  Eugene Kholmovski ,  Christopher McGann ,  Joshua Blauer ,  Troy Badger ,  Robert Sillman Oakes ,  Nathan Burgon

IPC分类号： A61B5/055 ,  A61B6/00 ,  A61B5/02

CPC分类号： A61B6/503 ,  A61B5/055 ,  A61B6/037 ,  A61B6/504 ,  A61B8/0883 ,  A61B8/0891 ,  A61B17/12122 ,  A61B18/1492 ,  G01R33/4808

摘要： Certain embodiments provide a method of assessing an outcome of an ablative atrial fibrillation (AF) treatment modality administered to a patient, the method including: determining, from left atrium (LA) tissue image data of a subject patient that has undergone an ablative AF treatment with the modality, at least one of: a level of a parameter that is positively proportional or negatively proportional to an amount of ablated tissue in a wall of the LA of the subject patient; and a spatial distribution, in the LA wall, of a variable indicative of ablated LA tissue; and outputting, to an output device, a machine-readable indicator of at least one of: (i) a comparison between the determined level and a threshold level of the parameter; and (ii) a map of the spatial distribution.

摘要翻译： 某些实施方案提供评估施用于患者的消融性房颤（AF）治疗方式的结果的方法，所述方法包括：从经过消融性AF治疗的受试患者的左心房（LA）组织图像数据确定 与所述形态相关联的至少一个：与所述受试者患者的LA的壁中的消融组织的量成正比或成比例的参数水平; 以及在LA壁中的空间分布指示消融的LA组织的变量; 并且向输出设备输出以下至少一个的机器可读指示符：（i）所确定的电平与参数的阈值电平之间的比较; 和（ii）空间分布图。

公开(公告)号：US20100160765A1

公开(公告)日：2010-06-24

申请号：US12344164

申请日：2008-12-24

申请人： Nassir F. Marrouche ,  Rob Macleod ,  Eugene Kholmovski ,  Christopher McGann ,  Joshua Blauer ,  Troy Badger ,  Robert Sillman Oakes ,  Nathan Burgon

发明人： Nassir F. Marrouche ,  Rob Macleod ,  Eugene Kholmovski ,  Christopher McGann ,  Joshua Blauer ,  Troy Badger ,  Robert Sillman Oakes ,  Nathan Burgon

IPC分类号： A61B5/055 ,  A61B5/02

CPC分类号： G06T7/0012 ,  G06T7/41 ,  G06T2207/10088 ,  G06T2207/30048

摘要： Certain embodiments of the invention provide methods of assessing a patient's risk for atrial fibrillation (AF) recurrence after receiving treatment with an AF treatment modality, that include determining, from left atrium (LA) tissue image data of a patient, a level of a parameter that is positively proportional to an amount of unhealthy tissue in a wall of the LA of the patient; and outputting, to an output device, an indicator of a comparison between (i) the determined level and (ii) a first threshold level of the parameter, the first threshold level derived from LA tissue image data of at least one other patient, who experienced an AF recurrence after treatment with the AF treatment modality. In certain embodiments, levels of the parameter equal to or greater than the first threshold level are indicative of a significant risk of AF recurrence after treatment with the AF treatment modality.

摘要翻译： 本发明的某些实施方案提供了在接受AF治疗方式的治疗后评估患者心房颤动（AF）复发风险的方法，其包括从左心房（LA）组织中确定患者的图像数据，参数水平 这与患者的LA的壁中的不健康组织的量成正比; 以及将（i）所确定的等级和（ii）所述参数的第一阈值水平之间的比较的指示符，从至少一个其他患者的LA组织图像数据导出的第一阈值水平， AF治疗后经AF复发。 在某些实施方案中，参数等于或大于第一阈值水平的水平指示用AF治疗模式治疗后AF复发的显着风险。