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公开(公告)号：US20100113867A1
公开(公告)日：2010-05-06
申请号：US12606047
申请日：2009-10-26
申请人： MICHAEL V. WILES , ROBERT TAFT , EVA M. EICHER , SHANNON BYERS
发明人： MICHAEL V. WILES , ROBERT TAFT , EVA M. EICHER , SHANNON BYERS
摘要： The present invention provides novel methods of maintaining genetic stability of non-human animal inbred strains. In the methods, pedigree-tracked cryopreserved embryos or gametes or pre-gametes derived from a foundation colony are produced and used to re-establish the foundation colony at appropriate intervals.
摘要翻译： 本发明提供了维持非人类动物近交系的遗传稳定性的新方法。 在这些方法中，产生了谱系跟踪的冷冻保存的胚胎或来自基础菌落的配子或配子，并用于以合适的间隔重新建立基础菌落。
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公开(公告)号：US08552254B2
公开(公告)日：2013-10-08
申请号：US12606047
申请日：2009-10-26
申请人： Michael V. Wiles , Robert Taft , Eva M. Eicher , Shannon Byers
发明人： Michael V. Wiles , Robert Taft , Eva M. Eicher , Shannon Byers
IPC分类号： C12N15/00 , A01K67/00 , A01K67/027
摘要： The present invention provides novel methods of maintaining genetic stability of non-human animal inbred strains. In the methods, pedigree-tracked cryopreserved embryos or gametes or pre-gametes derived from a foundation colony are produced and used to re-establish the foundation colony at appropriate intervals.
摘要翻译： 本发明提供了维持非人类动物近交系的遗传稳定性的新方法。 在这些方法中，产生了谱系跟踪的冷冻保存的胚胎或来自基础菌落的配子或配子，并用于以合适的间隔重新建立基础菌落。
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公开(公告)号：US20100095389A1
公开(公告)日：2010-04-15
申请号：US12536909
申请日：2009-08-06
申请人： Michael Wiles , Robert Taft , Eva M. Eicher
发明人： Michael Wiles , Robert Taft , Eva M. Eicher
IPC分类号： A01K67/02 , A01K67/027
摘要： The present invention provides novel methods of maintaining genetic stability of non-human animal inbred strains. In the methods, pedigree-tracked cryopreserved embryos derived from a foundation colony are produced and used to re-establish the foundation colony at appropriate intervals.
摘要翻译： 本发明提供了维持非人类动物近交系的遗传稳定性的新方法。 在该方法中，产生源自基础菌落的系谱跟踪的低温保存的胚胎并用于以合适的间隔重新建立基础菌落。
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公开(公告)号：US20120180146A1
公开(公告)日：2012-07-12
申请号：US13373997
申请日：2011-12-05
申请人： Michael V. Wiles , Robert Taft , Eva M. Eicher
发明人： Michael V. Wiles , Robert Taft , Eva M. Eicher
IPC分类号： A01K67/027 , A01K67/02
摘要： The present invention provides novel methods of maintaining genetic stability of non-human animal inbred strains. In the methods, pedigree-tracked cryopreserved embryos derived from a foundation colony are produced and used to re-establish the foundation colony at appropriate intervals.
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公开(公告)号：US08110721B2
公开(公告)日：2012-02-07
申请号：US12536909
申请日：2009-08-06
申请人： Michael V. Wiles , Robert Taft , Eva M. Eicher
发明人： Michael V. Wiles , Robert Taft , Eva M. Eicher
IPC分类号： A01K67/027 , A01K67/00 , C12N15/00
摘要： The present invention provides novel methods of maintaining genetic stability of non-human animal inbred strains. In the methods, pedigree-tracked cryopreserved embryos derived from a foundation colony are produced and used to re-establish the foundation colony at appropriate intervals.
摘要翻译： 本发明提供了维持非人类动物近交系的遗传稳定性的新方法。 在该方法中，产生源自基础菌落的系谱跟踪的低温保存的胚胎并用于以合适的间隔重新建立基础菌落。
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公开(公告)号：US07592501B2
公开(公告)日：2009-09-22
申请号：US10915840
申请日：2004-08-11
申请人： Michael V. Wiles , Robert Taft , Eva M. Eicher
发明人： Michael V. Wiles , Robert Taft , Eva M. Eicher
IPC分类号： G01N33/00 , A01K67/00 , A01K67/027
摘要： The present invention provides novel methods of maintaining genetic stability of non-human animal inbred strains. In the methods, pedigree-tracked cryopreserved embryos derived from a foundation colony are produced and used to re-establish the foundation colony at appropriate intervals.
摘要翻译： 本发明提供了维持非人类动物近交系的遗传稳定性的新方法。 在该方法中，产生源自基础菌落的系谱跟踪的低温保存的胚胎并用于以合适的间隔重新建立基础菌落。
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