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公开(公告)号：US20250057392A1
公开(公告)日：2025-02-20
申请号：US18935672
申请日：2024-11-04
Applicant: FUJIFILM Corporation , FUJITA ACADEMY
Inventor： Yuichi TERAMURA , Yohei OTAKA , Hitoshi KAGAYA , Seiko SHIBATA
Abstract: An endoscope system that illuminates an object and captures reflected light from the object includes a control processor. The control processor acquires an examination image and determines whether the examination image shows a swallowing state or a non-swallowing state. In addition, the control processor detects a high pixel value region from the examination image and determines that the examination image shows the swallowing state in a case in which an area of the high pixel value region is equal to or greater than a first threshold value. Further, the control processor performs grayscale conversion on the examination image to obtain a grayscale image and performs a binarization process for obtaining the high pixel value region in a case in which a density value of a pixel of the grayscale image is equal to or greater than a second threshold value.
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公开(公告)号：US12205289B2
公开(公告)日：2025-01-21
申请号：US17664312
申请日：2022-05-20
Applicant: Fujita Academy , Canon Medical Systems Corporation
Inventor： Kazuhiro Katada , Satoru Nakanishi
IPC: G06T7/00 , G06T5/70 , G06T5/90 , G06V10/774
Abstract: According to one embodiment, a medical information processing method generates a high-contrast image by applying conversion processing to a first medical image captured by a first diagnostic apparatus and having a first contrast in a region of interest, the high-contrast image having a contrast higher than a contrast of a second medical image obtained by a second diagnostic apparatus. The method generates a pseudo second medical image by applying image processing to the high-contrast image, the pseudo second medical image simulating the second medical image and having a second contrast lower than the first contrast. The method trains a model using the pseudo second medical image as input data and the high-contrast image as ground truth data, and generates a trained model.
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公开(公告)号：US11814651B2
公开(公告)日：2023-11-14
申请号：US16490786
申请日：2018-03-07
Applicant: FUJITA ACADEMY
Inventor： Hideyuki Saya , Yoshimi Arima , Takashi Semba , Akiyoshi Kasuga
IPC: C12N5/071 , A01K67/027 , A61K49/00 , C12N5/095 , C12Q1/02
CPC classification number: C12N5/0689 , A01K67/027 , A61K49/0008 , C12N5/0695 , C12Q1/025 , A01K2207/12 , A01K2227/105 , A01K2267/0331 , C12N2500/30 , C12N2500/90 , C12N2501/11 , C12N2501/117 , C12N2506/27 , C12N2513/00
Abstract: Provided is an epithelial tissue stem cell derived from an adult, which lacks at least one tumor suppressor gene.
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公开(公告)号：US20220369904A1
公开(公告)日：2022-11-24
申请号：US17746940
申请日：2022-05-17
Applicant: FUJIFILM Corporation , FUJITA ACADEMY
Inventor： Yuichi TERAMURA , Yohei OTAKA , Hitoshi KAGAYA , Seiko SHIBATA
Abstract: An endoscope system that illuminates an object and captures reflected light from the object includes a control processor. The control processor acquires an examination image and determines whether the examination image shows a swallowing state or a non-swallowing state. In addition, the control processor detects a high pixel value region from the examination image and determines that the examination image shows the swallowing state in a case in which an area of the high pixel value region is equal to or greater than a first threshold value. Further, the control processor performs grayscale conversion on the examination image to obtain a grayscale image and performs a binarization process for obtaining the high pixel value region in a case in which a density value of a pixel of the grayscale image is equal to or greater than a second threshold value.
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公开(公告)号：US11191804B2
公开(公告)日：2021-12-07
申请号：US16960417
申请日：2018-12-28
Applicant: FUJITA ACADEMY
Inventor： Kazuhiro Sugihara , Naohiro Kanayama , Toshiaki Shibata , Yuichiro Onodera
Abstract: An object of the present invention is to provide a peptide drug that is able to selectively induce apoptosis in target cells. The present invention is a cytocidal agent containing a fusion peptide of an endosome escape peptide and an apoptosis-inducing peptide, which consists of an amino acid sequence represented by SEQ ID NO: 1, and the said cytocidal agent as a therapeutic agent for a disease caused by abnormal proliferation of cells.
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Patent Agency Ranking
公开(公告)号：US20200330549A1
公开(公告)日：2020-10-22
申请号：US16960417
申请日：2018-12-28
Applicant: FUJITA ACADEMY
Inventor： Kazuhiro SUGIHARA , Naohiro KANAYAMA , Toshiaki SHIBATA , Yuichiro ONODERA
Abstract: An object of the present invention is to provide a peptide drug that is able to selectively induce apoptosis in target cells. The present invention is a cytocidal agent containing a fusion peptide of an endosome escape peptide and an apoptosis-inducing peptide, which consists of an amino acid sequence represented by SEQ ID NO: 1, and the said cytocidal agent as a therapeutic agent for a disease caused by abnormal proliferation of cells.
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公开(公告)号：US20180296169A1
公开(公告)日：2018-10-18
申请号：US15951334
申请日：2018-04-12
Applicant: Canon Medical Systems Corporation , FUJITA ACADEMY
Inventor： Takashi ICHIHARA , Yoshihiro IKEDA , Takuya SAKAGUCHI
Abstract: A medical image processing apparatus according to an embodiment includes processing circuitry. The processing circuitry sets a first region of interest in a region corresponding to cardiac muscle on a cross-section of a heart included in image data. The processing circuitry further sets a second region of interest that is larger than the first region of interest in a region including the region. The processing circuitry determines a threshold for determining a range of signal values used for blood flow dynamic analysis on the image data based on a frequency distribution of signal values in the first region of interest. The processing circuitry carries out blood flow dynamic analysis on the second region of interest using signal values included in a range based on the threshold.
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公开(公告)号：US20230126237A1
公开(公告)日：2023-04-27
申请号：US17995043
申请日：2021-03-31
Applicant: FUJITA ACADEMY , National University Corporation Tokai National Higher Education and Research System
Inventor： Yu KODANI , Hiroshi NAGASAKI , Hidetaka SUGA
Abstract: The present invention provides a method for efficiently separating and purifying functional pituitary hormone-producing cells and/or progenitor cells thereof from differentiated tissues derived from pluripotent stem cells.
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公开(公告)号：US20220383501A1
公开(公告)日：2022-12-01
申请号：US17804650
申请日：2022-05-31
Applicant: FUJITA ACADEMY , CANON MEDICAL SYSTEMS CORPORATION
Inventor： Yoshiharu OHNO , Kota AOYAGI
Abstract: A medical information display apparatus according to an embodiment includes processing circuitry. The processing circuitry is configured to display information on the basis of volume data including at least a lung. The processing circuitry is configured to display a first index value based on an anatomical structure of the lung and a second index value based on the volume data related to the lung, so as to be kept in correspondence with each other.
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公开(公告)号：US20220000576A1
公开(公告)日：2022-01-06
申请号：US17289440
申请日：2019-10-29
Applicant: Capsulacare LLC , Fujita Academy
Inventor： Kyongtae BAE , Junu BAE , Sonu BAE , Shizuko NAGAO , Kanako KUMAMOTO , Aya YOSHIMURA , Tamio YAMAGUCHI
IPC: A61B90/00
Abstract: A method for treatment or prevention of diseases accompanying abnormal growth of a body organ or mass. Specifically, a method of manufacturing a capsule device to encase a body organ such as kidney, liver and ovary is provided. Abnormal growth of a body organ is slowed or halted by covering the body organ such as kidney, liver and ovary. The diseases associated with abnormal growth include, for example, polycystic kidney disease and polycystic liver disease.
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