公开(公告)号：US07417428B2

公开(公告)日：2008-08-26

申请号：US10554354

申请日：2004-04-22

申请人： Frank Gerardus Cornelis Hoogenraad ,  Arianne Margarethe Corinne Van Muiswinkel ,  Ronaldus Frederik Johannes Holthuizen ,  Johan Samuel Van Den Brink

发明人： Frank Gerardus Cornelis Hoogenraad ,  Arianne Margarethe Corinne Van Muiswinkel ,  Ronaldus Frederik Johannes Holthuizen ,  Johan Samuel Van Den Brink

IPC分类号： G01V3/00

CPC分类号： G01R33/56341 ,  G01R33/4806

摘要： A method of deriving a directional structure from an object dataset is proposed. The object dataset assigns local directions to positions in a multidimensional geometrical space. For example the local directions concern local flow directions in a diffusion tensor magnetic resonance image at least one ‘region of interest’ is selected on the basis of spatial functional information, such as an fMRI image, time correlation of an fMRI image series with a functional paradigm or an anatomical image. These ‘region of interest’ are employed to initialize a fibre tracking to derive the directional structure that represents the nervous fibre system.

摘要翻译： 提出了从对象数据集导出定向结构的方法。 对象数据集将本地方向分配给多维几何空间中的位置。 例如，局部方向涉及扩散张量磁共振图像中的局部流动方向，基于空间功能信息来选择至少一个“感兴趣区域”，例如fMRI图像，fMRI图像序列与功能性的时间相关性 范式或解剖图像。 这些“感兴趣的区域”用于初始化光纤跟踪以导出代表神经纤维系统的定向结构。

公开(公告)号：US07477054B2

公开(公告)日：2009-01-13

申请号：US11568280

申请日：2005-04-22

申请人： Frank Gerardus Cornelis Hoogenraad ,  Johan Samuel Van Den Brink

发明人： Frank Gerardus Cornelis Hoogenraad ,  Johan Samuel Van Den Brink

IPC分类号： G01V3/00

CPC分类号： G01R33/4828 ,  G01R33/287

摘要： A magnetic resonance imaging system comprises a receiver system to acquire magnetic resonance signals. A control system controls the receiver system to reform an acquisition sequence to acquire the magnetic resonance signals in several acquisition segments. Respective groups of acquisition segments involve acquisition of magnetic resonance signals in different RF-receiver frequency bands. In the respective groups of acquisition segments, magnetic resonance signals are acquired from different nuclei having different gyromagnetic ratios. According to the invention, reconstruction of different types of information carried by the respective nuclei is made possible. For example, imaging of the anatomy of a patient to be examined is performed on the basis of proton magnetic resonance imaging. Imaging of a targeted contrast agent is achieved on the basis of 19F magnetic resonance imaging. Localisation of a invasive device, such as a catheter, is also performed on the basis of e.g. 19F magnetic resonance imaging.

摘要翻译： 磁共振成像系统包括用于获取磁共振信号的接收器系统。 控制系统控制接收机系统改造采集序列以获取几个采集段中的磁共振信号。 获取段的各组涉及在不同的RF接收机频带中获取磁共振信号。 在相应的采集段组中，从具有不同回旋磁比的不同核获取磁共振信号。 根据本发明，由各个核承载的不同类型的信息的重构成为可能。 例如，基于质子磁共振成像进行被检查患者的解剖结构的成像。 在19F磁共振成像的基础上实现靶向造影剂的成像。 侵入性装置（例如导管）的定位也基于例如导管进行。 19F磁共振成像。

公开(公告)号：US20080252291A1

公开(公告)日：2008-10-16

申请号：US10597570

申请日：2005-01-31

申请人： Frank Gerardus Cornelis Hoogenraad ,  Ronaldus Frederik Johannes Holthuizen ,  Robert Brijder

发明人： Frank Gerardus Cornelis Hoogenraad ,  Ronaldus Frederik Johannes Holthuizen ,  Robert Brijder

IPC分类号： G01R33/563

CPC分类号： G01R33/56341

摘要： A magnetic resonance imaging method involves acquisition of magnetic resonance signals with application of diffusion weighting at a plurality of diffusion weighting strengths diffusion directions. An object dataset is reconstructed from the magnetic resonance signals in which apparent diffusion coefficients are assigned. The occurrence of one single or several diffusion directions in identified for individual voxels. In this way account is taken of crossing fibres.

摘要翻译： 磁共振成像方法包括在多个扩散加权强度扩散方向上应用扩散加权来获取磁共振信号。 从其中分配表观扩散系数的磁共振信号重建对象数据集。 为个体体素识别出一个单个或多个扩散方向的发生。 以这种方式考虑交叉纤维。