Compounds useful for treating neurodegenerative disorders
    1.
    发明申请
    Compounds useful for treating neurodegenerative disorders 失效
    可用于治疗神经变性疾病的化合物

    公开(公告)号:US20070010503A1

    公开(公告)日:2007-01-11

    申请号:US11434726

    申请日:2006-05-16

    IPC分类号: A61K31/58 C07J71/00

    摘要: As described herein, the present invention provides compounds useful for treating or lessening the severity of a neurodegenerative disorder. The present invention also provides methods of treating or lessening the severity of such disorders wherein said method comprises administering to a patient a compound of the present invention, or composition thereof. Said method is useful for treating or lessening the severity of, for example, Alzheimer's disease.

    摘要翻译: 如本文所述,本发明提供了可用于治疗或减轻神经变性疾病严重程度的化合物。 本发明还提供了治疗或减轻此类疾病严重程度的方法,其中所述方法包括向患者施用本发明化合物或其组合物。 所述方法可用于治疗或减轻例如阿尔茨海默病的严重性。

    Measuring appliance comprising a dynamic sighting functionality and associated method

    公开(公告)号:US09829314B2

    公开(公告)日:2017-11-28

    申请号:US13993014

    申请日:2012-01-10

    IPC分类号: G01C11/00 G01C15/00

    CPC分类号: G01C11/00 G01C15/002

    摘要: According to the invention, the construction measuring device has a functionality for modifying the orientation of the sighting unit in a manually controllable manner, within the framework of which the orientation of the sighting unit is dynamically modified by the first or second rotary drive, according to a current direction and a current distance from a defined central anchor display point to a currently marked display point. The respective current direction defines an orientation modifying direction and the respective current distance defines an orientation modifying speed for changing the orientation of the sighting unit.

    Compounds useful for treating neurodegenerative disorders
    6.
    发明授权
    Compounds useful for treating neurodegenerative disorders 失效
    可用于治疗神经变性疾病的化合物

    公开(公告)号:US07851641B2

    公开(公告)日:2010-12-14

    申请号:US11434726

    申请日:2006-05-16

    IPC分类号: C07J53/00 A61K36/00

    摘要: As described herein, the present invention provides compounds useful for treating or lessening the severity of a neurodegenerative disorder. The present invention also provides methods of treating or lessening the severity of such disorders wherein said method comprises administering to a patient a compound of the present invention, or composition thereof. Said method is useful for treating or lessening the severity of, for example, Alzheimer's disease.

    摘要翻译: 如本文所述,本发明提供了可用于治疗或减轻神经变性疾病严重程度的化合物。 本发明还提供了治疗或减轻此类疾病严重程度的方法,其中所述方法包括向患者施用本发明化合物或其组合物。 所述方法可用于治疗或减轻例如阿尔茨海默病的严重性。

    Device for measuring and marking space points along horizontally running contour lines
    8.
    发明授权
    Device for measuring and marking space points along horizontally running contour lines 有权
    沿着水平运行的轮廓线测量和标记空间点的装置

    公开(公告)号:US09207078B2

    公开(公告)日:2015-12-08

    申请号:US13884593

    申请日:2011-11-08

    摘要: A construction surveying device having a base, an upper part mounted on the base and can be rotated about an axis of rotation, a sighting unit having a laser source which is designed to emit a laser beam and a laser light detector, and an evaluation and control unit, a first rotary drive and a second rotary drive enable the upper part and the sighting unit to be driven and aligned, a spatial alignment of the sighting unit with respect to the base can be detected using two goniometers, and coordinates for space points can be determined using the evaluation and control unit, the construction surveying device has a horizontal line projection functionality which, at least sometimes, takes place automatically after triggering and is intended to measure and mark space points along a horizontal line, running in a horizontal plane, on an arbitrarily shaped surface.

    摘要翻译: 一种施工测量装置,具有基座,上部安装在基座上并且可围绕旋转轴线旋转,具有设计成发射激光束的激光源和激光检测器的瞄准单元,以及评估和 控制单元,第一旋转驱动器和第二旋转驱动器使得上部和瞄准单元能够被驱动和对准,可以使用两个测角器来检测瞄准单元相对于基座的空间对准,并且用于空间点的坐标 可以使用评估和控制单元来确定,施工测量装置具有水平线投影功能,其至少有时在触发之后自动发生,并且旨在测量并标记沿着水平线运行的水平线上的空间点 在任意形状的表面上。

    MEASURING APPLIANCE COMPRISING AN AUTOMATIC REPRESENTATION-CHANGING FUNCTIONALITY
    9.
    发明申请
    MEASURING APPLIANCE COMPRISING AN AUTOMATIC REPRESENTATION-CHANGING FUNCTIONALITY 有权
    包括自动更新功能的测量装置

    公开(公告)号:US20130293705A1

    公开(公告)日:2013-11-07

    申请号:US13979121

    申请日:2012-01-10

    IPC分类号: G01B11/24

    摘要: A measuring appliance in which inputted or measured spatial points and a horizontal projection representation or spatial representation of at least some spatial points from the quantity of spatial points can be displayed, said points being at least partially connected by lines. The measuring appliance has a representation-changing functionality in the framework of which, according to a line selected on the user side from the lines displayed in a horizontal projection representation or a spatial representation, in an automatically controlled manner by means of the evaluation and control unit: a virtual surface is defined by the selected line and a direction provided as the vertical; a subset of spatial points is selected from the quantity of spatial points, lying inside a buffer zone surrounding the virtual surface in a defined manner; and a vertical projection representation of exclusively such spatial points pertaining to the subset is displayed on the display.

    摘要翻译: 一种测量装置,其中可以显示来自空间点数量的至少一些空间点的输入或测量的空间点和水平投影表示或空间表示,所述点至少部分地通过线连接。 测量仪器具有代表变化功能,其框架根据在用户侧从通过水平投影表示或空间表示显示的线选择的线以自动控制的方式通过评估和控制 单位:虚拟表面由所选择的行和作为垂直方向提供的方向定义; 从定义的方式位于围绕虚拟表面的缓冲区内的空间点的数量中选择空间点的子集; 并且在显示器上显示专属于该子集的这样的空间点的垂直投影表示。

    MEASURING APPLIANCE COMPRISING A DYNAMIC SIGHTING FUNCTIONALITY AND ASSOCIATED METHOD
    10.
    发明申请
    MEASURING APPLIANCE COMPRISING A DYNAMIC SIGHTING FUNCTIONALITY AND ASSOCIATED METHOD 有权
    包含动态信号功能和相关方法的测量装置

    公开(公告)号:US20130278752A1

    公开(公告)日:2013-10-24

    申请号:US13993014

    申请日:2012-01-10

    IPC分类号: G01C11/00

    CPC分类号: G01C11/00 G01C15/002

    摘要: According to the invention, the construction measuring device has a functionality for modifying the orientation of the sighting unit in a manually controllable manner, within the framework of which the orientation of the sighting unit is dynamically modified by the first or second rotary drive, according to a current direction and a current distance from a defined central anchor display point to a currently marked display point. The respective current direction defines an orientation modifying direction and the respective current distance defines an orientation modifying speed for changing the orientation of the sighting unit.

    摘要翻译: 根据本发明,施工测量装置具有用于以可手动控制的方式改变瞄准单元的方向的功能,在其框架内,根据第一或第二旋转驱动器动态修改瞄准单元的定向 当前方向和从定义的中心锚点显示点到当前标记的显示点的当前距离。 相应的电流方向限定取向修改方向,并且相应的电流距离限定用于改变瞄准单元的取向的取向修改速度。