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公开(公告)号:US20050069547A1
公开(公告)日:2005-03-31
申请号:US10480465
申请日:2002-06-12
申请人: Franz Armbruster , Markus Karmatschek , Franz Nader , Ulf Forssmann , Mats Paulsson , Martin Berger
发明人: Franz Armbruster , Markus Karmatschek , Franz Nader , Ulf Forssmann , Mats Paulsson , Martin Berger
IPC分类号: C12N15/09 , A61K39/395 , A61K45/00 , A61K51/00 , A61P1/00 , A61P5/00 , A61P7/00 , A61P9/00 , A61P11/00 , A61P13/08 , A61P13/12 , A61P15/00 , A61P17/00 , A61P19/00 , A61P25/00 , A61P35/00 , A61P35/04 , C07K14/51 , C07K16/18 , A61K38/17
CPC分类号: C07K16/18 , A01K2217/05 , A61K2039/505 , C07K14/51 , C07K2317/11 , C07K2317/21
摘要: The invention relates to a medicament against tumors and their metastases, which preferentially settle in bone tissue, comprising as active ingredient at least one binding molecule which binds to bone sialoprotein or a fragment thereof in serum or plasma.
摘要翻译: 本发明涉及一种抗肿瘤及其转移的药物,其优先沉降于骨组织中,其包含与血清或血浆中的骨唾液酸蛋白或其片段结合的至少一种结合分子作为活性成分。