公开(公告)号：US07097609B2

公开(公告)日：2006-08-29

申请号：US10382511

申请日：2003-03-07

申请人： Johann Kindlein ,  Frits van Krieken ,  Arie Luite Visscher

发明人： Johann Kindlein ,  Frits van Krieken ,  Arie Luite Visscher

IPC分类号： A61N5/00 ,  G21F5/00

CPC分类号： G21F5/015 ,  A61N5/1007 ,  A61N2005/1008

摘要： The invention relates to an after loader apparatus for treatment of tumours in an animal body comprising a housing with at least one exchangeable radiation source connected to a first end of a transport wire, which wire is connected with its other end to transport means for advancing said transport wire and said radiation source through a guide tube to and from a tumour in said body, where at least the radiation source and the transport wire are mounted in an exchangeable radiation shielded after loader cartridge, which cartridge can be placed in a suitable receptable opening present in said housing.It is an object of the invention to provide an after loader apparatus wherein in a more safe manner to the environment a cartridge containing a radioactive source can be replaced by another cartridge containing a new radioactive source and according to the invention the after loader apparatus is characterized in that, for exchanging said radiation source after use an exchanging device is present for, in a first step, removing the cartridge with the used radiation source from said receptable opening and, in a second step, inserting a further cartridge containing a new radiation source in said receptable opening.The invention relates furthermore to a device for exchanging an after loader cartridge in an after loader apparatus according to the invention.

摘要翻译： 本发明涉及一种用于治疗动物体内的肿瘤的后装载装置，包括具有连接到输送线的第一端的至少一个可交换辐射源的壳体，该导线与其另一端连接到用于推进所述 输送线和所述辐射源通过导管连接到所述主体中的肿瘤，其中至少辐射源和输送线被安装在装载器盒之后屏蔽的可更换辐射中，所述可插入的辐射源可以放置在合适的可接收开口 存在于房屋内。 本发明的目的是提供一种后装载装置，其中以更安全的方式到达环境中，容纳放射源的筒可以被另一个包含新的放射源的筒代替，根据本发明，后装载装置的特征在于 其特征在于，为了在使用之后交换所述辐射源，存在交换装置，用于在第一步骤中用所述可接收的开口用所使用的辐射源去除所述盒，并且在第二步骤中，插入另外的包含新的辐射源的盒 在所述可接收的开口中。 本发明还涉及根据本发明的用于在后装载机装置中更换后装载机筒的装置。

公开(公告)号：US07267643B2

公开(公告)日：2007-09-11

申请号：US10452123

申请日：2003-06-03

申请人： Albert Dirk Adrianus Koster ,  Frits Van Krieken ,  Hans Martin Schot

发明人： Albert Dirk Adrianus Koster ,  Frits Van Krieken ,  Hans Martin Schot

IPC分类号： A61N5/00 ,  A61M36/00

CPC分类号： A61N5/1027 ,  A61N2005/1011

摘要： The invention relates to a method and apparatus for temporarily inserting and positioning at least one energy emitting source in an animal body, wherein the apparatus comprises at least: a hollow open needle having a proximal needle end and a distal needle end to be inserted into the body, so as to provide a channel in the body; a guide tube having a proximal guide tube end and a distal guide tube end to be inserted into the hollow open needle; the hollow open needle being retractable from the body over the guide tube; a first fixing element for fixating the guide tube with said proximal guide tube end relative to the body; a catheter tube having a closed distal catheter tube end and an open proximal catheter tube end to be inserted with its distal catheter tube end until a predetermined depth into the guide tube and the body via said proximal guide tube end and fixating the catheter tube to the guide tube; at least one energy emitting source for insertion into the catheter tube via said proximal catheter tube end and, which at least one energy emitting source is removed after a predetermined period of time from the catheter tube.According to the invention the hollow open needle and said guide tube are inserted through a part of said body leaving both proximal and distal ends of said guide tube exposed outside either sides of said part of said body, and a second fixing element for fixing the guide tube with said distal guide tube end relative to the body.

摘要翻译： 本发明涉及一种用于在动物体内临时插入和定位至少一个能量发射源的方法和装置，其中该装置至少包括：具有近端针端和远端针端的中空开口针， 身体，以便在身体中提供通道; 引导管，其具有近端引导管端和待插入中空开放针的远端引导管端; 所述中空开口针可从所述主体伸出所述导管; 第一固定元件，用于将所述引导管与所述近端引导管端相对于所述主体固定; 导管，其具有封闭的远端导管管端和开放的近端导管管端，以将其远端导管管端插入，直到通过所述近端引导管端到达导管和身体的预定深度并且将导管管固定到 导管; 至少一个能量发射源，用于经由所述近端导管管端插入所述导管管中，并且在从所述导管管预定的时间段之后，至少一个能量发射源被去除。 根据本发明，中空开口针和引导管插入穿过所述主体的一部分，使所述引导管的近端和远端暴露在所述主体的所述部分的任一侧的外侧，以及用于固定引导件的第二固定元件 管，其中所述远端引导管端相对于身体。

公开(公告)号：US20060014997A1

公开(公告)日：2006-01-19

申请号：US11167166

申请日：2005-06-28

申请人： Johann Kindlein ,  Frits Van Krieken

发明人： Johann Kindlein ,  Frits Van Krieken

IPC分类号： A61N5/00

CPC分类号： A61N5/1015

摘要： The invention relates to a device for radiation treatment of proliferative tissue surrounding a cavity in an animal body comprising at least an inflatable balloon system having a balloon wall for placement in said cavity; a supportive probe having an elongated body with a distal end connected with said inflatable balloon system and a proximal end remaining outside said cavity; inflation means for inflating and deflating said balloon system with a pressurized medium; radiation delivering means for placing at least one energy emitting source within said cavity for performing said radiation treatment. It is an object of the invention to provide a device for radiation treatment of proliferative tissue surrounding a cavity in an animal patient body according to the above preamble capable in controlling the real, actual status of the inflated balloon system present inside said body cavity, especially when said device is utilized with an after loading apparatus. The device is according to the invention characterized in that said device comprises monitoring means for monitoring the inflation status of the inflatable balloon system. Hence with the device according to the invention the actual inflation status of the inflated balloon system can be determined, providing accurate information about the operational conditions of the device during radiation treatments being performed in an animal body. Any malfunction can be easily detected thereby obviating the risk of any misadministration of a radiation dose to the patient.

摘要翻译： 本发明涉及一种用于放射治疗包围动物体腔内的增生组织的装置，该装置包括至少一个具有用于放置在所述空腔中的球囊壁的可膨胀球囊系统; 支撑探针，其具有细长体，其远端与所述可充气球囊系统连接，并且近端保持在所述空腔外; 膨胀装置用于用加压介质对所述球囊系统进行充气和放气; 辐射传送装置，用于将至少一个能量发射源放置在所述空腔内用于进行所述辐射处理。 本发明的一个目的是提供一种用于根据上述前序能够对动物患者体内空腔周围的增生组织进行放射治疗的装置，其能够控制存在于所述体腔内的充气球囊系统的实际状态，特别是 当所述装置与后装载装置一起使用时。 根据本发明的装置，其特征在于，所述装置包括用于监测可充气球囊系统的充气状态的监视装置。 因此，根据本发明的装置，可以确定充气球囊系统的实际充气状态，在动物体内执行放射治疗期间提供关于装置的操作条件的准确信息。 可以容易地检测到任何故障，从而避免了向患者施加辐射剂量的任何错误的风险。