公开(公告)号：US20120251580A1

公开(公告)日：2012-10-04

申请号：US13430938

申请日：2012-03-27

Applicant: Hafiz Ahmed ,  Prasun Guha ,  Engin Kaptan ,  Gerardo Vasta ,  Gargi Bandyopadhyaya

Inventor： Hafiz Ahmed ,  Prasun Guha ,  Engin Kaptan ,  Gerardo Vasta ,  Gargi Bandyopadhyaya

IPC: A61K39/00 ,  A61P35/04

CPC classification number: A61K39/0011 ,  A61K39/39558

Abstract: A Thomsen-Friedenreich disaccharide-containing glycopeptide purified from cod fish of approximately 100 kDa (designated TFD100) and methods of using the same in the suppression of cancer metastasis is disclosed.

Abstract translation: 公开了从约100kDa的鳕鱼（TFD100）中纯化的含有Thomsen-Friedenreich的含二糖的糖肽以及用于抑制癌症转移的方法。

公开(公告)号：US10905702B2

公开(公告)日：2021-02-02

申请号：US16258228

申请日：2019-01-25

Applicant: Gerardo Vasta ,  Lai-Xi Wang

Inventor： Gerardo Vasta ,  Lai-Xi Wang

IPC: A61K31/7004 ,  A61K31/7056 ,  A61K31/724 ,  A61P31/00 ,  A61P11/00 ,  A61K9/107 ,  A61K31/351 ,  A61K31/4192 ,  A61K31/7016 ,  A61K31/43 ,  A61K31/7036 ,  A61K31/7048 ,  A61K45/06

Abstract: Galectin 3 inhibitors and methods for treating sepsis using the same are provided herein.

公开(公告)号：US20060246496A1

公开(公告)日：2006-11-02

申请号：US11405238

申请日：2006-04-17

Applicant: Hafiz Ahmed ,  Gerardo Vasta

Inventor： Hafiz Ahmed ,  Gerardo Vasta

IPC: C12Q1/68 ,  G01N33/574

CPC classification number: G01N33/57434 ,  C12Q1/6886 ,  C12Q2600/112 ,  C12Q2600/154 ,  G01N2333/4724 ,  G01N2400/02

Abstract: A method and assay are described for determining prostate cancer and the general stage of progression of such cancer by quantifying levels of expression of different galectin isoforms and/or different levels of promoter methylation of such galectin isoforms.

公开(公告)号：US06326485B1

公开(公告)日：2001-12-04

申请号：US08900117

申请日：1997-07-25

Applicant: Gerardo Vasta ,  Adam G. Marsh ,  Joséto A. Fernández-Robledo ,  Cathleen A. Coss ,  Anita C. Wright

Inventor： Gerardo Vasta ,  Adam G. Marsh ,  Joséto A. Fernández-Robledo ,  Cathleen A. Coss ,  Anita C. Wright

IPC: C07H2104

CPC classification number: C12Q1/6893

Abstract: The present invention is directed to oligonucleotides used as amplification primers and assay probes for species-specific detection and identification of the protozoan Perkinsus in shellfish. The oligonucleotides are designed to preferentially hybridize to what has been found to be a species-unique sequence in the target organism's genome. Preferential hybridization means, for example, that the inventive primers amplify the target sequence in P. marinus with little or no detectable amplification of target sequences of other species of protozoa such as P. atlanticus thereby making the assay species specific.

Abstract translation: 本发明涉及用作扩增引物的寡核苷酸和用于物种特异性检测和鉴定贝类中原生动物Perkinsus的测定探针。 寡核苷酸被设计为优先与目标生物体基因组中已发现的物种独特序列杂交。 优先杂交是指，例如，本发明的引物扩增猪尾草杆菌中的靶序列，其中很少或不可检测到扩增其他种类的原生动物如大豆大蠊的靶序列，从而使测定物种具有特异性。

公开(公告)号：US20190142853A1

公开(公告)日：2019-05-16

申请号：US16258228

申请日：2019-01-25

Applicant: Gerardo VASTA ,  Lai-Xi WANG

Inventor： Gerardo VASTA ,  Lai-Xi WANG

IPC: A61K31/7004 ,  A61P31/00 ,  A61K31/4192 ,  A61P11/00 ,  A61K9/107 ,  A61K31/351 ,  A61K31/7016

Abstract: Galectin 3 inhibitors and methods for treating sepsis using the same are provided herein.

公开(公告)号：US09180175B2

公开(公告)日：2015-11-10

申请号：US13430938

申请日：2012-03-27

Applicant: Hafiz Ahmed ,  Prasun Guha ,  Engin Kaptan ,  Gerardo Vasta ,  Gargi Bandyopadhyaya

Inventor： Hafiz Ahmed ,  Prasun Guha ,  Engin Kaptan ,  Gerardo Vasta ,  Gargi Bandyopadhyaya

IPC: A01N37/18 ,  A61K39/00 ,  A61K39/395

CPC classification number: A61K39/0011 ,  A61K39/39558

Abstract: A Thomsen-Friedenreich disaccharide-containing glycopeptide purified from cod fish of approximately 100 kDa (designated TFD100) and methods of using the same in the suppression of cancer metastasis is disclosed.

Abstract translation: 公开了从约100kDa的鳕鱼（TFD100）中纯化的含有Thomsen-Friedenreich的含二糖的糖肽以及用于抑制癌症转移的方法。