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公开(公告)号：US20140256624A1
公开(公告)日：2014-09-11
申请号：US14157678
申请日：2014-01-17
Applicant: Rolf GREMPLER , Odd-Erik JOHANSEN , Thomas KLEIN , Gerd LUIPPOLD , Michael MARK
Inventor： Rolf GREMPLER , Odd-Erik JOHANSEN , Thomas KLEIN , Gerd LUIPPOLD , Michael MARK
IPC: A61K38/28 , A61K31/7048
CPC classification number: A61K38/28 , A61K31/341 , A61K31/7048 , A61K45/06 , A61K2300/00
Abstract: The invention relates to a pharmaceutical composition according to the claim 1 comprising an SGLT2 inhibitor and an insulin which is suitable in the treatment or prevention of one or more conditions selected from type 1 diabetes mellitus, type 2 diabetes mellitus, impaired glucose tolerance and hyperglycemia. In addition the present invention relates to methods for preventing or treating of metabolic disorders and related conditions
Abstract translation: 本发明涉及根据权利要求1的药物组合物，其包含适合于治疗或预防选自1型糖尿病，2型糖尿病，葡萄糖耐量异常和高血糖症的一种或多种病症的SGLT2抑制剂和胰岛素。 此外，本发明涉及用于预防或治疗代谢紊乱及相关病症的方法
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公开(公告)号：US20120283169A1
公开(公告)日：2012-11-08
申请号：US13287216
申请日：2011-11-02
Applicant: Rolf GREMPLER , Odd-Eric JOHANSEN , Thomas KLEIN , Gerd LUIPPOLD , Michael MARK
Inventor： Rolf GREMPLER , Odd-Eric JOHANSEN , Thomas KLEIN , Gerd LUIPPOLD , Michael MARK
IPC: A61K38/28 , A61P3/08 , A61P3/04 , A61P11/00 , A61P1/18 , A61P27/12 , A61P7/02 , A61P13/12 , A61P9/06 , A61P9/04 , A61P9/10 , A61P9/08 , A61P25/00 , A61P37/06 , A61P3/12 , A61P3/10
CPC classification number: A61K38/28 , A61K31/341 , A61K31/7048 , A61K45/06 , A61K2300/00
Abstract: The invention relates to a pharmaceutical composition according to the claim 1 comprising an SGLT2 inhibitor and an insulin which is suitable in the treatment or prevention of one or more conditions selected from type 1 diabetes mellitus, type 2 diabetes mellitus, impaired glucose tolerance and hyperglycemia. In addition the present invention relates to methods for preventing or treating of metabolic disorders and related conditions
Abstract translation: 本发明涉及根据权利要求1的药物组合物，其包含适合于治疗或预防选自1型糖尿病，2型糖尿病，葡萄糖耐量异常和高血糖症的一种或多种病症的SGLT2抑制剂和胰岛素。 此外，本发明涉及用于预防或治疗代谢紊乱及相关病症的方法
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公开(公告)号：US20140228286A1
公开(公告)日：2014-08-14
申请号：US14178321
申请日：2014-02-12
Applicant: Gerd Luippold , Peter NICKOLAUS , Ruediger STREICHER
Inventor： Gerd Luippold , Peter NICKOLAUS , Ruediger STREICHER
IPC: A61K31/519 , A61K45/06
CPC classification number: A61K31/519 , A61K31/527 , A61K45/06 , A61K2300/00
Abstract: A method of treating diabetes mellitus or a microvascular or macrovascular complication of diabetes mellitus in a patient in need thereof, the method comprising administering to the patient a compound of formula 1 wherein R1, R2, R3, and R4 are as defined in claim 1.
Abstract translation: 一种在有需要的患者中治疗糖尿病或糖尿病的微血管或大血管并发症的方法，所述方法包括向患者施用式1化合物，其中R 1，R 2，R 3和R 4如权利要求1所定义。
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Patent Agency Ranking
公开(公告)号：US20130035298A1
公开(公告)日：2013-02-07
申请号：US13539713
申请日：2012-07-02
Applicant: Uli BROEDL , Maximilian von EYNATTEN , Odd-Erik JOHANSEN , Thomas KLEIN , Gerd LUIPPOLD
Inventor： Uli BROEDL , Maximilian von EYNATTEN , Odd-Erik JOHANSEN , Thomas KLEIN , Gerd LUIPPOLD
IPC: A61K31/7048 , A61P13/12
CPC classification number: A61K31/7004
Abstract: The invention relates to the treatment or prevention of renal impairment and/or complications using a SGLT-2 inhibitor, for example in patients diagnosed with metabolic disorders and related conditions.
Abstract translation: 本发明涉及使用SGLT-2抑制剂治疗或预防肾损伤和/或并发症，例如诊断为代谢紊乱和相关病症的患者。
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公开(公告)号：US20130310398A1
公开(公告)日：2013-11-21
申请号：US13949579
申请日：2013-07-24
Applicant: Michael MARK , Peter EICKELMANN , Gerd LUIPPOLD , Leo THOMAS
Inventor： Michael MARK , Peter EICKELMANN , Gerd LUIPPOLD , Leo THOMAS
IPC: A61K31/522 , A61K31/506
CPC classification number: A61K31/522 , A61K31/506 , A61K45/06
Abstract: Combinations of DPP-4 inhibitors with GPR119 agonists, as well as to the use of these combinations for treating and/or preventing metabolic diseases, particularly diabetes (especially type 2 diabetes mellitus) and conditions related thereto.
Abstract translation: DPP-4抑制剂与GPR119激动剂的组合，以及这些组合用于治疗和/或预防代谢性疾病，特别是糖尿病（特别是2型糖尿病）和与此有关的病症的用途。
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公开(公告)号：US08513264B2
公开(公告)日：2013-08-20
申请号：US13062777
申请日：2009-09-08
Applicant: Michael Mark , Peter Eickelmann , Gerd Luippold , Leo Thomas
Inventor： Michael Mark , Peter Eickelmann , Gerd Luippold , Leo Thomas
IPC: A61K31/519
CPC classification number: A61K31/522 , A61K31/506 , A61K45/06
Abstract: The present invention relates to combinations of DPP-4 inhibitors with GPR119 agonists, as well as to the use of these combinations for treating and/or preventing metabolic diseases, particularly diabetes (especially type 2 diabetes mellitus) and conditions related thereto.
Abstract translation: 本发明涉及DPP-4抑制剂与GPR119激动剂的组合，以及这些组合用于治疗和/或预防代谢性疾病，特别是糖尿病（特别是2型糖尿病）和与此有关的病症的用途。
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7.发明申请Combination of a GPR119 Agonist and the DPP-IV Inhibitor Linagliptin for Use in the Treatment of Diabetes and Related Conditions 审中-公开GPR119激动剂与用于治疗糖尿病及相关病症的DPP-IV抑制剂Linagliptin的组合公开(公告)号：US20130109703A1
公开(公告)日：2013-05-02
申请号：US13634886
申请日：2011-03-18
Applicant: Peter Eickelmann , Gerd Luippold , Michael Mark , Leo Thomas
Inventor： Peter Eickelmann , Gerd Luippold , Michael Mark , Leo Thomas
IPC: A61K31/454 , A61K31/506 , A61K31/522
CPC classification number: A61K31/454 , A61K31/506 , A61K31/519 , A61K31/522 , A61K31/5383 , A61K45/06 , A61K2300/00
Abstract: The present invention relates to combinations of DPP-4 inhibitors with GPR119 agonists, as well as to the use of these combinations for treating and/or preventing metabolic diseases, particularly diabetes (especially type 2 diabetes mellitus) and conditions related thereto.
Abstract translation: 本发明涉及DPP-4抑制剂与GPR119激动剂的组合，以及这些组合用于治疗和/或预防代谢性疾病，特别是糖尿病（特别是2型糖尿病）和与此有关的病症的用途。
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公开(公告)号：US20110263617A1
公开(公告)日：2011-10-27
申请号：US13062777
申请日：2009-09-08
Applicant: Michael Mark , Peter Eickelmann , Gerd Luippold , Leo Thomas
Inventor： Michael Mark , Peter Eickelmann , Gerd Luippold , Leo Thomas
IPC: A61K31/519 , A61K31/437 , A61P9/12 , A61P3/10 , A61P3/04 , A61P3/06 , A61K31/506 , A61P3/00
CPC classification number: A61K31/522 , A61K31/506 , A61K45/06
Abstract: The present invention relates to combinations of DPP-4 inhibitors with GPR119 agonists, as well as to the use of these combinations for treating and/or preventing metabolic diseases, particularly diabetes (especially type 2 diabetes mellitus) and conditions related thereto.
Abstract translation: 本发明涉及DPP-4抑制剂与GPR119激动剂的组合，以及这些组合用于治疗和/或预防代谢性疾病，特别是糖尿病（特别是2型糖尿病）和与此有关的病症的用途。
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