公开(公告)号：US20100130370A1

公开(公告)日：2010-05-27

申请号：US12695553

申请日：2010-01-28

申请人： Eveline Schurmann-Mader ,  Andreas Peter Abel ,  Martin Andreas Bopp ,  Gert Ludwig Duveneck ,  Markus Ehrat ,  Gerhard Mtthias Kresbach ,  Michael Pawlak ,  Nania Graciela Scharer-Hernandez ,  Eginhard Schick

发明人： Eveline Schurmann-Mader ,  Andreas Peter Abel ,  Martin Andreas Bopp ,  Gert Ludwig Duveneck ,  Markus Ehrat ,  Gerhard Mtthias Kresbach ,  Michael Pawlak ,  Nania Graciela Scharer-Hernandez ,  Eginhard Schick

IPC分类号： C40B30/00 ,  C40B60/12

CPC分类号： B01L3/5025 ,  G01N21/05 ,  G01N21/253 ,  G01N2021/0346

摘要： A one- or two-dimensional arrangement of flow cells is provided, as part of an array of sample compartments, with at least one inlet and outlet for each sample compartment, formed by a base plate and a body, with an arrangement of spatial recesses corresponding to the (geometrical) arrangement of the sample compartments, combined with the base plate. The arrangement allows for supplying to or removing from the sample compartments, which can be arranged at a high quantity on a small base area, even very small amounts of samples or reagents. An arrangement of one or more sample compartments includes a base plate and a body combined with the base plate in such a way that one or more recesses for generation of one or more flow cells fluidically sealed against one another, each with at least one inlet and one outlet, are formed between the base plate and the body, wherein at least one outlet of each flow cell is joined with a reservoir fluidically connected with the flow cell, the reservoir being operable to receive liquid exiting the flow cell, besides methods for its manufacturing and their use.

摘要翻译： 提供了流动池的一维或二维布置，作为样品室阵列的一部分，每个样品室的至少一个入口和出口由基板和主体形成，具有空间凹陷的布置 对应于样品室的（几何）布置，与基板结合。 该装置允许从样品室供应或从样品室中取出，样品室可以大量排列在小的基底区域上，甚至是非常少量的样品或试剂。 一个或多个样品室的布置包括基板和与基板组合的主体，使得一个或多个凹槽用于产生流体密封的一个或多个流动池，每个具有至少一个入口和 一个出口形成在基板和主体之间，其中每个流动池的至少一个出口与与流动池流体连接的储存器连接，储存器可操作以接收离开流动池的液体，除了其用于其的方法 制造及其使用。