公开(公告)号：US08129376B2

公开(公告)日：2012-03-06

申请号：US12408486

申请日：2009-03-20

Applicant: Kumar Sundaresan ,  P. Bala Koteswara Rao ,  Bharathiraja Ainan ,  Hariharasubramanian Ayyamperumal ,  Girish A R ,  Srinivas Tatiparthy ,  Ganesh Prabhu ,  Hosahalli Subramanya ,  Alexander Bischoff

Inventor： Kumar Sundaresan ,  P. Bala Koteswara Rao ,  Bharathiraja Ainan ,  Hariharasubramanian Ayyamperumal ,  Girish A R ,  Srinivas Tatiparthy ,  Ganesh Prabhu ,  Hosahalli Subramanya ,  Alexander Bischoff

IPC: A61K31/5375 ,  A61K31/445 ,  C07D413/02 ,  C07D211/00

CPC classification number: C07D211/46 ,  C07D211/58 ,  C07D401/12 ,  C07D401/14 ,  C07D409/14 ,  C07D413/12 ,  C07D417/12

Abstract: The present invention relates to piperidine derivatives that act as inhibitors of stearoyl-CoA desaturase. The invention also relates to methods of preparing the compounds, compositions containing the compounds, and to methods of treatment using the compounds.

Abstract translation: 本发明涉及作为硬脂酰辅酶A去饱和酶抑制剂的哌啶衍生物。 本发明还涉及制备化合物的方法，含有该化合物的组合物以及使用该化合物的治疗方法。

公开(公告)号：US20090239810A1

公开(公告)日：2009-09-24

申请号：US12408486

申请日：2009-03-20

Applicant: Kumar Sundaresan ,  P.Bala Koteswara Rao ,  Bharathiraja Ainan ,  Hariharasubramanian Ayyamperumal ,  Girish A R ,  Srinivas Tatiparthy ,  Ganesh Prabhu ,  Hosahalli Subramanya ,  Alexander Bischoff

Inventor： Kumar Sundaresan ,  P.Bala Koteswara Rao ,  Bharathiraja Ainan ,  Hariharasubramanian Ayyamperumal ,  Girish A R ,  Srinivas Tatiparthy ,  Ganesh Prabhu ,  Hosahalli Subramanya ,  Alexander Bischoff

IPC: A61K38/05 ,  C07D211/44 ,  C07D211/58 ,  C07D413/12 ,  C07D401/12 ,  A61K31/445 ,  A61P3/04

CPC classification number: C07D211/46 ,  C07D211/58 ,  C07D401/12 ,  C07D401/14 ,  C07D409/14 ,  C07D413/12 ,  C07D417/12

Abstract: The present invention relates to piperidine derivatives that act as inhibitors of stearoyl-CoA desaturase. The invention also relates to methods of preparing the compounds, compositions containing the compounds, and to methods of treatment using the compounds.

Abstract translation: 本发明涉及作为硬脂酰辅酶A去饱和酶抑制剂的哌啶衍生物。 本发明还涉及制备化合物的方法，含有该化合物的组合物以及使用该化合物的治疗方法。