公开(公告)号：US20130228474A1

公开(公告)日：2013-09-05

申请号：US13410609

申请日：2012-03-02

申请人： Scott SLOSS ,  Russell BAIN ,  Graeme WEBSTER

发明人： Scott SLOSS ,  Russell BAIN ,  Graeme WEBSTER

IPC分类号： G01N27/327 ,  G01N33/66

CPC分类号： G01N27/3272 ,  G01N33/66 ,  G01N2400/00

摘要： An analytical test strip (“ATT”) for use with a test meter includes a first insulating layer, with a first insulating layer upper surface, and a first electrically conductive layer (“ECL”) disposed thereon. The first ECL includes a first electrode portion (“EP”) and an electrical contact pad in electrical communication with the first EP. The ATT also includes a patterned spacer layer disposed above the first ECL that includes (i) a distal portion defining a bodily fluid sample-receiving chamber therein that overlies the first EP and (ii) an insulating proximal portion with an upper surface having a second ECL disposed thereon. The second ECL includes an interlayer contact portion and an electrical contact pad. A third ECL of the ATT includes a second EP and a proximal portion that overlies the interlayer contact portion. The second EP is disposed overlying and exposed to the sample-receiving chamber in an opposing relationship to the first EP.

摘要翻译： 与测试仪一起使用的分析测试条（“ATT”）包括具有第一绝缘层上表面的第一绝缘层和设置在其上的第一导电层（“ECL”）。 第一ECL包括与第一EP电连接的第一电极部分（“EP”）和电接触焊盘。 ATT还包括设置在第一ECL上方的图案化间隔层，其包括（i）在其中限定其中覆盖第一EP的体液样品接收室的远端部分，以及（ii）绝缘近端部分，其上表面具有第二 ECL置于其上。 第二ECL包括层间接触部分和电接触焊盘。 ATT的第三ECL包括覆盖层间接触部分的第二EP和近端部分。 第二EP以与第一EP相对的关系设置为覆盖并暴露于样品接收室。

公开(公告)号：US20110094882A1

公开(公告)日：2011-04-28

申请号：US12606496

申请日：2009-10-27

申请人： Gavin MACFIE ,  Graeme WEBSTER ,  Marco F. CARDOSI ,  Christopher Philip LEACH ,  Steven SETFORD ,  Selwayan SAINI

发明人： Gavin MACFIE ,  Graeme WEBSTER ,  Marco F. CARDOSI ,  Christopher Philip LEACH ,  Steven SETFORD ,  Selwayan SAINI

IPC分类号： G01N33/50

CPC分类号： G01N27/3272 ,  G01N2035/00118

摘要： A test meter for use with a dual-chamber, multi-analyte test strip includes a test strip receiving module and a signal processing module. The test strip receiving module has a first electrical connector configured for contacting a first analyte contact pad of a first working electrode of the test strip; a second electrical connector configured for contacting a second analyte contact pad of a second working electrode of the test strip, a third electrical connector configured for contacting a first counter/reference contact pad of a first counter/reference electrode layer of the test strip, and a fourth electrical connector configured for contacting a second counter/reference contact pad of a second counter/reference electrode layer of the test strip. The signal processing module is configured to receive a first signal via the first electrical connector and the third electrical connector and employ the first signal for the determination of a first analyte (such as glucose) in a bodily fluid sample (for example, whole blood sample) applied to the dual-chamber, multi-analyte test strip. Moreover, the signal processing module is also configured to receive a second signal via the second electrical connector and fourth electrical connector and employ the second signal for the determination of a second analyte (e.g., a ketone analyte) in the bodily fluid sample applied to the dual-chamber, multi-analyte test strip. Furthermore, the third and fourth electrical contacts provide contact in an opposing manner.

摘要翻译： 用于双腔多分析物测试条的测试仪包括测试条接收模块和信号处理模块。 测试条接收模块具有第一电连接器，其被配置用于接触测试条的第一工作电极的第一分析物接触焊盘; 第二电连接器，其被配置用于接触测试条的第二工作电极的第二分析物接触焊盘;第三电连接器，其被配置用于接触测试条的第一计数器/参考电极层的第一计数器/参考接触焊盘，以及 第四电连接器，其被配置为接触测试条的第二计数器/参考电极层的第二计数器/参考接触焊盘。 信号处理模块被配置为经由第一电连接器和第三电连接器接收第一信号，并且采用第一信号来确定体液样品中的第一分析物（例如葡萄糖）（例如，全血样品 ）应用于双室多分析物测试条。 此外，信号处理模块还被配置为经由第二电连接器和第四电连接器接收第二信号，并且使用第二信号来确定施加到所述第二电连接器和第四电连接器的体液样品中的第二分析物（例如，酮分析物） 双室多分析物测试条。 此外，第三和第四电触点以相反的方式提供接触。

公开(公告)号：US08632664B2

公开(公告)日：2014-01-21

申请号：US12606496

申请日：2009-10-27

申请人： Gavin Macfie ,  Graeme Webster ,  Marco F. Cardosi ,  Christopher Philip Leach ,  Steven Setford ,  Selwayan Saini

发明人： Gavin Macfie ,  Graeme Webster ,  Marco F. Cardosi ,  Christopher Philip Leach ,  Steven Setford ,  Selwayan Saini

IPC分类号： G01N27/327

CPC分类号： G01N27/3272 ,  G01N2035/00118

摘要： A test meter for use with a dual-chamber, multi-analyte test strip includes a test strip receiving module and a signal processing module. The test strip receiving module has a first electrical connector configured for contacting a first analyte contact pad of a first working electrode of the test strip; a second electrical connector configured for contacting a second analyte contact pad of a second working electrode of the test strip, a third electrical connector configured for contacting a first counter/reference contact pad of a first counter/reference electrode layer of the test strip, and a fourth electrical connector configured for contacting a second counter/reference contact pad of a second counter/reference electrode layer of the test strip. The signal processing module is configured to receive a first signal via the first electrical connector and the third electrical connector and employ the first signal for the determination of a first analyte (such as glucose) in a bodily fluid sample (for example, whole blood sample) applied to the dual-chamber, multi-analyte test strip. Moreover, the signal processing module is also configured to receive a second signal via the second electrical connector and fourth electrical connector and employ the second signal for the determination of a second analyte (e.g., a ketone analyte) in the bodily fluid sample applied to the dual-chamber, multi-analyte test strip. Furthermore, the third and fourth electrical contacts provide contact in an opposing manner.

摘要翻译： 用于双腔多分析物测试条的测试仪包括测试条接收模块和信号处理模块。 测试条接收模块具有第一电连接器，其被配置用于接触测试条的第一工作电极的第一分析物接触焊盘; 第二电连接器，其被配置用于接触测试条的第二工作电极的第二分析物接触焊盘;第三电连接器，其被配置用于接触测试条的第一计数器/参考电极层的第一计数器/参考接触焊盘，以及 第四电连接器，其被配置为接触测试条的第二计数器/参考电极层的第二计数器/参考接触焊盘。 信号处理模块被配置为经由第一电连接器和第三电连接器接收第一信号，并且采用第一信号来确定体液样品中的第一分析物（例如葡萄糖）（例如，全血样品 ）应用于双室多分析物测试条。 此外，信号处理模块还被配置为经由第二电连接器和第四电连接器接收第二信号，并且使用第二信号来确定施加到所述第二电连接器和第四电连接器的体液样品中的第二分析物（例如，酮分析物） 双室多分析物测试条。 此外，第三和第四电触点以相反的方式提供接触。

公开(公告)号：US20120312699A1

公开(公告)日：2012-12-13

申请号：US13154875

申请日：2011-06-07

申请人： Graeme WEBSTER ,  Peter TEMPLETON ,  David ELDER ,  Lawrence RITCHIE ,  James MOFFAT ,  Gavin MACFIE

发明人： Graeme WEBSTER ,  Peter TEMPLETON ,  David ELDER ,  Lawrence RITCHIE ,  James MOFFAT ,  Gavin MACFIE

IPC分类号： G01N27/28 ,  G01N33/66

CPC分类号： G01N27/3273

摘要： An analytical test strip and test meter combination for use in the determination of an analyte in a bodily fluid sample includes an analytical test strip and a test meter, and a method for determination thereof. The analytical test strip has an electrode, a first electrical contact pad in electrical communication with the electrode and configured to communicate an electrical response of the electrode to the test meter; and a second electrical contact pad in electrical communication with the electrode and configured to communicate an electrical response of the electrode to the test meter should the test meter be in electrical communication with the second electrical contact pad. In addition, the second electrical contact pad has electrical continuity with the first electrical contact pad and the first and second electrical contact pads are disposed in either of first and second predetermined spatial relationships to one another.

摘要翻译： 用于测定体液样品中的分析物的分析测试条和测试仪组合包括分析测试条和测试仪，以及用于确定其的方法。 分析测试条具有电极，与电极电连通的第一电接触焊盘，并被配置为将电极的电响应传递到测试仪; 以及第二电接触焊盘，其与所述电极电连通并且被配置为如果所述测试仪器与所述第二电接触焊盘电气连通，则将所述电极的电响应传达到所述测试仪表。 此外，第二电接触焊盘与第一电接触焊盘具有电连续性，并且第一和第二电接触焊盘彼此以第一和第二预定空间关系中的任一个布置。

公开(公告)号：US09217723B2

公开(公告)日：2015-12-22

申请号：US13410609

申请日：2012-03-02

申请人： Scott Sloss ,  Russell Bain ,  Graeme Webster

发明人： Scott Sloss ,  Russell Bain ,  Graeme Webster

IPC分类号： G01N27/327

CPC分类号： G01N27/3272 ,  G01N33/66 ,  G01N2400/00

摘要： An analytical test strip (“ATT”) for use with a test meter includes a first insulating layer, with a first insulating layer upper surface, and a first electrically conductive layer (“ECL”) disposed thereon. The first ECL includes a first electrode portion (“EP”) and an electrical contact pad in electrical communication with the first EP. The ATT also includes a patterned spacer layer disposed above the first ECL that includes (i) a distal portion defining a bodily fluid sample-receiving chamber therein that overlies the first EP and (ii) an insulating proximal portion with an upper surface having a second ECL disposed thereon. The second ECL includes an interlayer contact portion and an electrical contact pad. A third ECL of the ATT includes a second EP and a proximal portion that overlies the interlayer contact portion. The second EP is disposed overlying and exposed to the sample-receiving chamber in an opposing relationship to the first EP.

摘要翻译： 与测试仪一起使用的分析测试条（“ATT”）包括具有第一绝缘层上表面的第一绝缘层和设置在其上的第一导电层（“ECL”）。 第一ECL包括与第一EP电连接的第一电极部分（“EP”）和电接触焊盘。 ATT还包括设置在第一ECL上方的图案化间隔层，其包括（i）在其中限定其中覆盖第一EP的体液样品接收室的远端部分，以及（ii）绝缘近端部分，其上表面具有第二 ECL置于其上。 第二ECL包括层间接触部分和电接触焊盘。 ATT的第三ECL包括覆盖层间接触部分的第二EP和近端部分。 第二EP以与第一EP相对的关系设置为覆盖并暴露于样品接收室。

公开(公告)号：US20110094896A1

公开(公告)日：2011-04-28

申请号：US12606467

申请日：2009-10-27

申请人： Gavin MACFIE ,  Graeme Webster ,  Marco F. Cardosi ,  Christopher Philip Leach ,  Steven Setford ,  Selwayan Saini

发明人： Gavin MACFIE ,  Graeme Webster ,  Marco F. Cardosi ,  Christopher Philip Leach ,  Steven Setford ,  Selwayan Saini

IPC分类号： G01N27/26

CPC分类号： G01N27/3272 ,  G01N2035/00118

摘要： A dual chamber, multi-analyte test strip has a first insulating layer, a first electrically conductive layer, with a first working electrode, disposed on the first insulating layer and a first patterned spacer layer positioned above the first electrically conductive layer. The first patterned spacer layer has a first sample-receiving chamber, with first and second end openings, defined therein that overlies the first working electrode. The test strip also includes a first counter/reference electrode layer that is exposed to the first sample receiving chamber and is in an opposing relationship to the first working electrode. The test strip further includes a counter/reference insulating layer disposed over the first counter/reference electrode layer and a second counter/reference electrode layer disposed on the counter/reference substrate. Also included in the test strip is a second patterned spacer layer that is positioned above the second counter/reference electrode layer. The second patterned spacer layer has a second sample-receiving chamber, with first and second end openings, defined therein. The test strip additionally has a second electrically conductive layer, with a second working electrode, disposed above the second patterned spacer layer, a second insulating layer disposed above the second electrically conductive layer, a first analyte reagent layer disposed on the first working electrode within the first sample-receiving chamber; and a second analyte reagent layer disposed on the second working electrode within the second sample-receiving chamber. The second counter/reference electrode layer is exposed to the second sample receiving chamber and is in an opposing relationship to the second working electrode.

摘要翻译： 双室多分析物测试条具有设置在第一绝缘层上的第一绝缘层，第一导电层和第一工作电极，以及位于第一导电层上方的第一图案化间隔层。 第一图案化间隔层具有第一样品接收室，其中限定在其中的第一和第二端部开口覆盖在第一工作电极上。 测试条还包括暴露于第一样品接收室并与第一工作电极相对关系的第一计数器/参考电极层。 测试条还包括设置在第一计数器/参考电极层上的计数器/参考绝缘层和设置在反向/参考基板上的第二计数器/参考电极层。 还包括在测试条中的是位于第二计数器/参考电极层上方的第二图案化间隔层。 第二图案化间隔层具有第二样品接收室，其中限定有第一和第二端部开口。 测试条另外具有第二导电层，第二工作电极设置在第二图案化间隔层上方，设置在第二导电层上方的第二绝缘层，设置在第二工作电极内的第一分析物试剂层， 第一采样室; 以及设置在第二样品接收室内的第二工作电极上的第二分析物试剂层。 第二计数器/参考电极层暴露于第二样品接收室，并且与第二工作电极相对。

公开(公告)号：US20110079522A1

公开(公告)日：2011-04-07

申请号：US12572534

申请日：2009-10-02

申请人： Graeme WEBSTER ,  Marco F. Cardosi ,  Selwayan Saini

发明人： Graeme WEBSTER ,  Marco F. Cardosi ,  Selwayan Saini

IPC分类号： G01N27/26 ,  G01N33/50

CPC分类号： C12Q1/006

摘要： A co-facial multi-analyte test strip includes a first insulating layer with an electrically conductive layer disposed thereon. The electrically conductive layer includes a first working electrode with a first analyte contact pad and a second working electrode with a second analyte contact pad. In addition, the first and second working electrodes of the electrically conductive layer are disposed on the first insulating layer in a planar inline configuration. The multi-analyte test strip also includes a patterned spacer layer positioned above the electrically conductive layer, with the patterned spacer layer defining a single bodily fluid sample-receiving chamber therein that overlies the first working electrode and the second working electrode. The multi-analyte test strip further includes a shared counter/reference electrode layer overlying and exposed to the bodily-fluid sample receiving chamber and configured in an opposing relationship to the first and second working electrodes; and a second insulating layer disposed above the shared counter/reference electrode layer. Moreover, the co-facial multi-analyte test strip also has a multi-analyte reagent layer disposed on the electrically conductive layer with the multi-analyte reagent layer having a first analyte reagent portion disposed on the first working electrode within the sample-receiving chamber and a second analyte reagent layer disposed the second working electrode within the sample-receiving chamber.

摘要翻译： 共面多分析物测试条包括其上设置有导电层的第一绝缘层。 导电层包括具有第一分析物接触焊盘的第一工作电极和具有第二分析物接触焊盘的第二工作电极。 此外，导电层的第一工作电极和第二工作电极以平面一字排列配置在第一绝缘层上。 多分析物测试条还包括位于导电层上方的图案化间隔层，其中图案化间隔层在其中限定了位于第一工作电极和第二工作电极之间的单个体液样品接收室。 所述多分析物测试条还包括共享的对/参照电极层，所述共用的计数器/参考电极层覆盖并暴露于所述体液样本接收室并且被配置成与所述第一和第二工作电极相对的关系; 以及设置在共享的计数器/参考电极层上方的第二绝缘层。 此外，共面多分析物测试条还具有设置在导电层上的多分析物试剂层，多分析物试剂层具有设置在样品接收室内的第一工作电极上的第一分析物试剂部分 以及将第二工作电极设置在样品接收室内的第二分析物试剂层。

公开(公告)号：US08323467B2

公开(公告)日：2012-12-04

申请号：US12606467

申请日：2009-10-27

申请人： Gavin MacFie ,  Graeme Webster ,  Marco F. Cardosi ,  Christopher Philip Leach ,  Steven Setford ,  Selwayan Saini

发明人： Gavin MacFie ,  Graeme Webster ,  Marco F. Cardosi ,  Christopher Philip Leach ,  Steven Setford ,  Selwayan Saini

IPC分类号： G01N27/327

CPC分类号： G01N27/3272 ,  G01N2035/00118

摘要： A dual chamber, multi-analyte test strip has a first insulating layer, a first electrically conductive layer, with a first working electrode, disposed on the first insulating layer and a first patterned spacer layer positioned above the first electrically conductive layer. The first patterned spacer layer has a first sample-receiving chamber, with first and second end openings, defined therein that overlies the first working electrode. The test strip also includes a first counter/reference electrode layer that is exposed to the first sample receiving chamber and is in an opposing relationship to the first working electrode. The test strip further includes a counter/reference insulating layer disposed over the first counter/reference electrode layer and a second counter/reference electrode layer disposed on the counter/reference substrate. Also included in the test strip is a second patterned spacer layer that is positioned above the second counter/reference electrode layer. The second patterned spacer layer has a second sample-receiving chamber, with first and second end openings, defined therein. The test strip additionally has a second electrically conductive layer, with a second working electrode, disposed above the second patterned spacer layer, a second insulating layer disposed above the second electrically conductive layer, a first analyte reagent layer disposed on the first working electrode within the first sample-receiving chamber; and a second analyte reagent layer disposed on the second working electrode within the second sample-receiving chamber. The second counter/reference electrode layer is exposed to the second sample receiving chamber and is in an opposing relationship to the second working electrode.

摘要翻译： 双室多分析物测试条具有设置在第一绝缘层上的第一绝缘层，第一导电层和第一工作电极，以及位于第一导电层上方的第一图案化间隔层。 第一图案化间隔层具有第一样品接收室，其中限定在其中的第一和第二端部开口覆盖在第一工作电极上。 测试条还包括暴露于第一样品接收室并与第一工作电极相对关系的第一计数器/参考电极层。 测试条还包括设置在第一计数器/参考电极层上的计数器/参考绝缘层和设置在反向/参考基板上的第二计数器/参考电极层。 还包括在测试条中的是位于第二计数器/参考电极层上方的第二图案化间隔层。 第二图案化间隔层具有第二样品接收室，其中限定有第一和第二端部开口。 测试条另外具有第二导电层，第二工作电极设置在第二图案化间隔层上方，设置在第二导电层上方的第二绝缘层，设置在第二工作电极内的第一分析物试剂层， 第一采样室; 以及设置在第二样品接收室内的第二工作电极上的第二分析物试剂层。 第二计数器/参考电极层暴露于第二样品接收室，并且与第二工作电极相对。