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1.发明申请公开(公告)号：US20120135536A1
公开(公告)日：2012-05-31
申请号：US13304859
申请日：2011-11-28
CPC分类号： B82Y30/00 , G01N21/553 , G01N21/554 , G01N21/75
摘要： A sensor for use in detecting and analyzing predetermined chemical substances is presented. The sensor comprises: a first structure configured for binding to a certain substance and comprising a substantially transparent substrate with respect to electromagnetic radiation of a predetermined wavelength range and a plurality of metallic islands deposited onto the transparent substrate and having a first spectral transmission profile with respect to the electromagnetic radiation of the predetermined wavelength range; the metallic islands comprising metallic films having a thickness selected such that binding of said certain substance to the first structure provides a change in a localized surface plasmon extinction in the metallic films being in a predetermined correlation with a change in a spectral transmission profile of the electromagnetic radiation of the predetermined wavelength range transmitted through the first structure and the substance as compared to said first spectral transmission profile, thereby enabling detection of said substance.
摘要翻译： 提出了一种用于检测和分析预定化学物质的传感器。 所述传感器包括：第一结构，其被配置为结合某一物质并且包括相对于预定波长范围的电磁辐射的基本上透明的基底和沉积在所述透明基底上的多个金属岛，并且具有与第 对于预定波长范围的电磁辐射; 金属岛包括具有选择的厚度的金属膜，使得所述某些物质与第一结构的结合提供金属膜中的局部表面等离子体激元消光的变化，其与电磁波的光谱透射分布的变化具有预定的相关性 与所述第一光谱透射曲线相比，通过第一结构和物质传输的预定波长范围的辐射，从而能够检测所述物质。
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2.发明授权公开(公告)号：US08071391B2
公开(公告)日：2011-12-06
申请号：US09922220
申请日：2001-08-03
IPC分类号： G01N33/553
CPC分类号： B82Y30/00 , G01N21/553 , G01N21/554 , G01N21/75
摘要： This invention seeks to provide methods and apparatus for analysis. Electromagnetic radiation is transmitted through a plurality of metallic islands on a transparent substrate. A resultant optical property of the plurality of metallic islands is measured. Thereafter a chemical substance is adsorbed onto the plurality of metallic islands so as to produce a chemical substance-metallic islands moiety.Electromagnetic radiation is transmitted through the chemical substance-metallic islands moiety and a resultant optical property of metallic islands in the chemical substance-metallic islands moiety is measured. The resultant optical property of the metallic islands in chemical substance-metallic islands moiety and the resultant optical property of the plurality of metallic islands are employed so as to provide at least one of a quantitative indication and a qualitative indication of at least one of: the chemical substance-metallic islands moiety, a functionality of the chemical substance-metallic islands moiety, the plurality of metallic islands, a functionality of the plurality of metallic islands, the chemical substance and a functionality of the chemical substance.
摘要翻译： 本发明寻求提供用于分析的方法和装置。 电磁辐射通过透明基板上的多个金属岛传播。 测量多个金属岛的合成光学特性。 此后，化学物质被吸附到多个金属岛上，以便产生化学物质 - 金属岛部分。 电磁辐射通过化学物质 - 金属岛部分传输，并测量化学物质 - 金属岛部分中金属岛的合成光学性质。 采用化学物质 - 金属岛部分中的金属岛的所得光学性质和多个金属岛的所得光学性质，以提供以下至少一个的定量指示和定性指示中的至少一个： 化学物质 - 金属岛部分，化学物质 - 金属岛部分的功能，多个金属岛，多个金属岛的官能团，化学物质和化学物质的功能。
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