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公开(公告)号:US6160116A
公开(公告)日:2000-12-12
申请号:US459692
申请日:1995-06-02
IPC分类号: C07D475/04
CPC分类号: C07D475/04
摘要: The invention relates to a process for preparing (6S)-folinic acid and its salts by recrystallization of alkaline-earth salts of (6R,S)-folinic acid and, where necessary, liberation of the acid from the alkaline-earth folinates and/or, where necessary, conversion into the alkali salts by at least one recrystallization in the presence of a base. The invention also relates to calcium-, magnesium-, potassium- and sodium-(6S)-folinates and to (6S)-folinic acid prepared in accordance with the invention.
摘要翻译: 本发明涉及一种通过(6R,S) - 赖氨酸的碱土金属盐的重结晶和必要时从碱土金属叶酸和/或碱土金属盐释放酸来制备(6S) - 丝氨酸及其盐的方法, 或者如果需要,在碱的存在下通过至少一次重结晶转化成碱金属盐。 本发明还涉及根据本发明制备的钙,镁,钾和钠 - (6S) - 叶酸和(6S) - 丝氨酸。
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公开(公告)号:US4189591A
公开(公告)日:1980-02-19
申请号:US6533
申请日:1979-01-25
IPC分类号: C07D233/54 , C07D233/64
CPC分类号: C07D233/64
摘要: The yield of 4-methyl-5-hydroxymethyl-imidazole from the known reaction between formaldehyde and 4-methyl-imidazole can be increased greatly if the reaction is performed in a concentrated aqueous medium at pH 11-13.5, preferably 12-13.5, at a temperature of 20.degree.-60.degree. C., preferably 30.degree.-40.degree. C., with an amount of formaldehyde not exceeding 1.5 mole per mole of 4-methyl-imidazole.
摘要翻译: 如果反应在pH 11-13.5,优选12-13.5的浓缩水性介质中进行,甲醛和4-甲基 - 咪唑之间已知反应的4-甲基-5-羟甲基咪唑的产率可大大提高 温度为20°-60℃,优选30°-40℃,甲醛量不超过1.5摩尔/摩尔4-甲基 - 咪唑。
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公开(公告)号:US07090770B2
公开(公告)日:2006-08-15
申请号:US10276701
申请日:2001-01-23
IPC分类号: B01D39/08
CPC分类号: B01D39/08 , B01D25/001 , B01D25/164 , B01D2201/34 , B01D2239/0208 , B01D2239/0216 , B01D2239/065 , B01D2239/0654 , B01D2239/0659 , B01D2239/1216
摘要: The invention relates to a filter cloth for a filter press and to a method for producing said filter cloth. The inventive filter cloth has a filtration section through which the filtrate reaches a filter element of the filter press, and an edging section which rests against the edge of the filter element. The filtration area is provided with a cloth that differs from that of the edging section. The filtration area is woven from monofil yarns while multifil yarns are woven into the edging section.
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公开(公告)号:US4602089A
公开(公告)日:1986-07-22
申请号:US582229
申请日:1984-02-21
IPC分类号: C07D233/90 , C07D473/00 , C07D473/02 , A61K31/52
CPC分类号: C07D473/00 , C07D233/90
摘要: There are prepared compounds of the formulae ##STR1## where R is lower alkyl, chlorine, or bromine and n is an integer from 1 to 5. The compounds of formula (1) can be used to make erythro-9-(2-hydroxy-3-nonyl) hypoxanthine and its homologues and also to make the compounds of formulae (2) and (3). All three classes of compounds are useful as immunomodulators.
摘要翻译: 制备式为“IMAGE”(1.)
(2.)或 (3.)的化合物,其中R为低级烷基,氯或溴,n为1至5的整数。 式(1)化合物可用于制备赤-9(2-羟基-3-壬基)次黄嘌呤及其同系物,并制备式(2)和(3)的化合物。 所有三类化合物都可用作免疫调节剂。 -
公开(公告)号:US4451478A
公开(公告)日:1984-05-29
申请号:US357679
申请日:1982-03-12
IPC分类号: C07D233/90 , C07D473/00 , C07D231/10 , A61K31/415
CPC分类号: C07D473/00 , C07D233/90
摘要: There are prepared compounds of the formulae ##STR1## where R is lower alkyl, chlorine, or bromine and n is an integer from 1 to 5. The compounds of formula (1) can be used to make erythro-9-(2-hydroxy-3-nonyl) hypoxanthine and its homologues and also to make the compounds of formulae (2) and (3). All three classes of compounds are useful as immunomodulators.
摘要翻译: 制备式为“IMAGE”(1.)
(2.)或 (3.)的化合物,其中R为低级烷基,氯或溴,n为1至5的整数。 式(1)化合物可用于制备赤-9(2-羟基-3-壬基)次黄嘌呤及其同系物,并制备式(2)和(3)的化合物。 所有三类化合物都可用作免疫调节剂。
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