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公开(公告)号：US20230190848A1
公开(公告)日：2023-06-22
申请号：US18069902
申请日：2022-12-21
发明人： Susana FIORENTINO GÓMEZ , Claudia Patricia URUEÑA PINZÓN , Alfonso BARRETO PRIETO , Karol PRIETO SARMIENTO , Alejandra GOMEZ CADENA , Ricardo BALLESTEROS-RAMIREZ , Angel Alberto GARCIA PENA , Pablo ASCHNER , Cindy Mayerly AREVALO OLAYA , Paola Veronica LASSO APRAEZ
IPC分类号： A61K36/48 , A61K31/192 , A61K31/216
CPC分类号： A61K36/48 , A61K31/192 , A61K31/216 , A61K2236/39 , A61K2236/31
摘要： The present invention provides compositions and methods for treating or prevent SARS-CoV-2 infections by delivering a therapeutically effective amount of a standardized P2Et extract enriched in polyphenol compounds from Caesalpinia spinosa that inhibits the production of coronavirus particles, reduces pulmonary fibrosis markers, down-regulates pro-inflammatory cytokines, and increases CD3+TL and CD3+CD4−CD8− T Lymphocytes subsets in COVID-19 patients. The disclosed compositions for treating or prevent SARS-CoV-2 infections comprising a standardized P2Et extract enriched in polyphenol compounds from Caesalpinia spinosa that may comprise one or more compounds selected from galloyl quinic acid and gallic acid derivatives and pharmaceutically acceptable excipients.
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公开(公告)号：US20160324680A1
公开(公告)日：2016-11-10
申请号：US14706563
申请日：2015-05-07
IPC分类号： A61F5/56
CPC分类号： A61F5/56
摘要： The present invention belongs to the field of medicine and relates to a method for the treatment of the obstruction of the airway, specially moderated obstructive sleep apnea/hypopnea syndrome (OSAHS) in adult patients, by using a soft cervical collar. The method of the invention achieves a significant reduction of the apnea/hypopnea index (AHI) in adult patients diagnosed with obstructive sleep apnea of moderate level.
摘要翻译： 本发明属于医学领域，涉及一种用于治疗成人患者气道梗阻，特别是缓解型阻塞性睡眠呼吸暂停/呼吸不足综合症（OSAHS）的方法，通过使用软颈颈。 本发明的方法在诊断为中度程度的阻塞性睡眠呼吸暂停的成人患者中实现呼吸暂停/呼吸不足指数（AHI）的显着降低。
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公开(公告)号：US20170091935A1
公开(公告)日：2017-03-30
申请号：US15350687
申请日：2016-11-14
发明人： Ricardo Antonio Mendoza Leon , Luis Felipe Uriza Carrasco , Phillipe Charles Douek , Marcela Hernández Hoyos
CPC分类号： G06T7/0012 , A61B6/032 , A61B6/5205 , G06K9/4604 , G06T7/11 , G06T2207/10081 , G06T2207/30004 , G06T2207/30092 , G06T2207/30242
摘要： A computer-based method is herein disclosed, allowing to differentiate automatically between two tissues of interest: an extrinsic and an intrinsic tissue, from a plurality of images, obtaining a quantitative assessment of each of said tissues without requiring the intervention of an expert. Said method involves the definition of a differentiation region in images obtained from a medical imaging acquisition device using a parametric contour, after which differentiation and quantification are carried out based on the photometric characteristics of the different tissues observed in images, evaluating the local neighborhood of each voxel belonging to the differentiation region previously defined in the plurality of images. The disclosed method increases to a great extent precision in differentiation and quantification of tissues, while the shown percentage error is considered tolerable for diagnostic purposes.
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公开(公告)号：US20150183259A1
公开(公告)日：2015-07-02
申请号：US14583440
申请日：2014-12-26
IPC分类号： B42F7/02
CPC分类号： B42F7/02
摘要： The present utility model belongs to the field of medicine and consists of an item that facilitates interaction/communication between physicians and patients during the time different medical treatments that patients should undergo are performed and include stages within medical facilities and stages in the place of residence. Said item consists of a folder or ‘logbook’ that allows storing in an ordered fashion all elements that emerge during the time in which a patient should undergo a particular medical treatment and should be handled in a controlled manner to avoid communication errors between physicians and patients, and therefore for encouraging the development and successful completion of such medical treatment.
摘要翻译： 本实用新型属于医学领域，包括在患者应进行不同医疗治疗期间促进医师与患者之间的相互作用/沟通的项目，包括医疗设施和居住地阶段的阶段。 所述项目包括文件夹或“日志”，其允许以有序的方式存储在患者应经历特定医疗的时间期间出现的所有元素，并且应以受控的方式处理以避免医生和患者之间的通信错误 ，因此鼓励发展并顺利完成这种治疗。
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公开(公告)号：US10007985B2
公开(公告)日：2018-06-26
申请号：US15350687
申请日：2016-11-14
发明人： Ricardo Antonio Mendoza Leon , Luis Felipe Uriza Carrasco , Phillipe Charles Douek , Marcela Hernández Hoyos
CPC分类号： G06T7/0012 , A61B6/032 , A61B6/5205 , G06K9/4604 , G06T7/11 , G06T2207/10081 , G06T2207/30004 , G06T2207/30092 , G06T2207/30242
摘要： A computer-based method is herein disclosed, allowing to differentiate automatically between two tissues of interest: an extrinsic and an intrinsic tissue, from a plurality of images, obtaining a quantitative assessment of each of said tissues without requiring the intervention of an expert. Said method involves the definition of a differentiation region in images obtained from a medical imaging acquisition device using a parametric contour, after which differentiation and quantification are carried out based on the photometric characteristics of the different tissues observed in images, evaluating the local neighborhood of each voxel belonging to the differentiation region previously defined in the plurality of images. The disclosed method increases to a great extent precision in differentiation and quantification of tissues, while the shown percentage error is considered tolerable for diagnostic purposes.
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