公开(公告)号：US5665388A

公开(公告)日：1997-09-09

申请号：US555900

申请日：1995-11-13

申请人： Howard P. Phykitt

发明人： Howard P. Phykitt

IPC分类号： A61K9/00 ,  A61K9/16 ,  A61K9/20

CPC分类号： A61K9/0095 ,  A61K31/616 ,  A61K9/1611

摘要： A method of manufacturing a stabilized, essentially sodium free, granular aspirin compound mixed with a granular potassium bicarbonate compound comprising the steps of determining a desirable dose size of such aspirin compound which is to be packaged. Weighing out an amount of granular aspirin based on the dose size determined. Placing an amount of such granular potassium bicarbonate compound into a container which is uniformly distributed over a bottom surface of such container to a predetermined depth. Placing such container into a heat treating apparatus. Heat treating the granular potassium bicarbonate compound at a temperature which is at least sufficient to convert an outer surface layer of such granular potassium bicarbonate compound to potassium carbonate and for a time which is at least sufficient to ensure that essentially all of such outer surface layer of the granular potassium bicarbonate compound is converted to such potassium carbonate. Weighing out an amount of such heat treated granular potassium bicarbonate compound based on the dose size determined. Placing the granular aspirin into a package and, thereafter, placing such heat treated granular potassium bicarbonate compound into such package thereby forming the stabilized, essentially sodium free, granular aspirin compound mixed with a granular potassium bicarbonate compound.

摘要翻译： 制备与颗粒状碳酸氢钾化合物混合的稳定化的，基本上无钠的粒状阿司匹林化合物的方法，包括确定所述待包装的阿司匹林化合物的期望剂量大小的步骤。 根据测定的剂量大小，称量一定量的粒状阿司匹林。 将一定量的这种颗粒状碳酸氢钾化合物放入容器中，该容器均匀地分布在这种容器的底表面上至预定的深度。 将这种容器放入热处理装置中。 在至少足以将这种颗粒状碳酸氢钾化合物的外表面层转化为碳酸钾的温度下热处理颗粒状碳酸氢钾化合物至少足以确保基本上所有这些外表面层 颗粒状碳酸氢钾化合物转化成这样的碳酸钾。 根据测定的剂量大小量取出一定量的这种经热处理的颗粒状碳酸氢钾化合物。 将颗粒状阿司匹林置于包装中，然后将这种经热处理的颗粒状碳酸氢钾化合物置于该包装中，由此形成与颗粒状碳酸氢钾化合物混合的稳定的，基本上无钠的粒状阿司匹林化合物。

公开(公告)号：US06386187B1

公开(公告)日：2002-05-14

申请号：US09680717

申请日：2000-10-06

申请人： Howard P. Phykitt

发明人： Howard P. Phykitt

IPC分类号： F02M2704

CPC分类号： F02M27/02 ,  F02B3/06 ,  F02M27/045

摘要： A device and process is provided for treatment of a hydrocarbon or fossil fuel which is to be combusted in a combustion chamber to improve combustion of the fuel in the combustion chamber by turbulently treating the fuel with a plurality of fields of magnetic flux and subjecting the fuel to a field of differing standard electrochemical reduction potentials. The device is adapted to be connected in-line in a fuel supply line of the combustion chamber and comprises: a non-magnetic, elongate hollow tubular housing having a longitudinal axis, opposing inlet and outlet ends, a generally centrally located inlet aperture in said inlet end for receiving fuel and a generally centrally located outlet aperture in said outlet end for dispensing treated fuel; a plurality of longitudinally elongated magnets located in the housing on opposing sides of the longitudinal axis providing a series of differing or alternating fields of magnetic flux along the longitudinal axis and providing opposing, facing pole faces of the magnets for contact with the fuel; and optionally, but preferably, at least two large surface area non-ferrous metal wool or screen materials of differing standard electrochemical reduction potentials in the housing, the metals being located along the longitudinal axis of the housing and between the magnets of the plurality of magnets and establishing a field of standard electrochemical reduction potential differential in the housing through which the fuel must flow. The device may also comprise axially spaced, radially extending, apertured flow controllers for directly turbulent flow of fuel through the screen materials and the series of alternating field of magnetic flux.

摘要翻译： 提供了一种装置和方法，用于处理在燃烧室中燃烧的烃或化石燃料，以通过用多个磁通场湍流处理燃料并对燃料进行处理以改善燃烧室中燃料的燃烧 到不同标准电化学还原电位的领域。 该装置适于在燃烧室的燃料供应管线中成直线连接，并且包括：非磁性细长的中空管状壳体，其具有纵向轴线，相对的入口端和出口端，所述 用于接收燃料的入口端和用于分配经处理的燃料的所述出口端中的大致中心定位的出口孔;多个纵向细长磁体，位于壳体的纵向轴线的相对侧上，提供一系列不同或交替的磁通量 所述纵向轴线并提供与所述燃料接触的所述磁体的相对的面对的极面; 并且可选地，但优选地，壳体中具有不同标准电化学还原电位的至少两个大的表面积有色金属棉或丝网材料，金属沿壳体的纵向轴线和多个磁体的磁体之间以及 在壳体中建立标准电化学还原电位差的领域，燃料必须通过该领域流动。该装置还可以包括轴向间隔开的径向延伸的有孔流量控制器，用于通过筛网材料直接湍流燃料流和一系列交替场 磁通量。

公开(公告)号：US5687841A

公开(公告)日：1997-11-18

申请号：US559003

申请日：1995-11-16

申请人： Howard P. Phykitt

发明人： Howard P. Phykitt

IPC分类号： A45F3/20 ,  B65D27/00 ,  B65D81/00 ,  A61K31/60

CPC分类号： A45F3/20 ,  B65D27/00

摘要： In combination with an alkaline and aspirin combination compound the improvement of a package which serves as both a shipping container for an individual dosage of such medication and at least one of a mixing vessel for mixing such individual dosage with a requisite volume of a liquid solvent and for serving as a drinking cup. The package includes a back portion formed of a material impervious to such liquid solvent and a front portion, also formed of a material impervious to such liquid solvent, overlaying such back portion. Such front portion and such back portion being joined together substantially at a common periphery to form a closed envelope structure with such individual dosage sealed within such closed envelope structure between the front portion and such back portion. This envelope structure adapted to be opened at one edge to convert it to an open-topped envelope structure. Additionally, the front portion and the back portion are adapted to be bowed apart at least sufficient to effect a predetermined volume within such open-topped envelope structure. Such open-topped envelope structure having such volume therein adapted to receive such requisite volume of liquid solvent thereto to be admixed with and dissolve such medication therein and be retained within this open-topped envelope structure.

摘要翻译： 与碱性和阿司匹林联合化合物组合，改进了用作这种药物的单独剂量的运输容器的包装，以及用于将这种单独剂量与所需体积的液体溶剂混合的混合容器和 用作饮用杯。 该包装包括由不透液体的液体溶剂形成的后部，以及由不透过这种液体溶剂的材料形成的前部，覆盖该后部。 这种前部和后部基本上在共同的周边连接在一起以形成封闭的包络结构，其中这种单独的剂量密封在前部和后部之间的封闭包络结构内。 该包络结构适于在一个边缘处打开以将其转换成开顶的包络结构。 此外，前部部分和后部部分适于被弯曲分开，至少足以在这种开顶的包络结构内实现预定的体积。 这种具有这种体积的敞开的包络结构适于接收这种所需体积的液体溶剂以与其混合并溶解这种药物，并保留在该开顶的包络结构内。

公开(公告)号：US5723453A

公开(公告)日：1998-03-03

申请号：US557726

申请日：1995-11-13

申请人： Howard P. Phykitt

发明人： Howard P. Phykitt

IPC分类号： A61K9/00 ,  A61K31/60

CPC分类号： A61K9/0095 ,  A61K31/616

摘要： A stabilized, essentially sodium free, alkaline and aspirin combination compound which is readily soluble in a preselected fluid, which when dissolved forms potassium acetylsalicylate. Such alkaline and aspirin combination compound consisting essentially of aspirin, having a predetermined particle size. Such aspirin being present in the alkaline and aspirin combination compound generally within a range of between about 325.0 mg and about 1,000.0 mg per unit dose. A preselected alkaline compound is present in such alkaline and aspirin combination compound generally within a range of between about 250.0 mg and about 3,000.0 mg per unit dose. The preselected alkaline compound having a ph generally within a range of between about 8.0 and 10.0 and such preselected alkaline compound being present in this alkaline and aspirin combination compound in a molar amount which is greater than a molar amount required to neutralize the aspirin.

摘要翻译： 稳定的，基本上不含钠，碱性和阿司匹林的组合化合物，其易溶于预选的液体，当溶解时形成乙酰水杨酸钾。 这种基本上由阿司匹林组成的碱性和阿司匹林联合化合物具有预定的粒径。 这种阿司匹林存在于碱性和阿司匹林联合化合物中，通常在每单位剂量约325.0mg至约1,000.0mg的范围内。 预先选择的碱性化合物存在于这种碱性和阿司匹林联合化合物中，通常在每单位剂量约250.0mg至约3,000.0mg的范围内。 预选的碱性化合物，其ph通常在约8.0和10.0之间，并且这种预选的碱性化合物以大于中和阿司匹林所需的摩尔量的摩尔量存在于该碱性和阿司匹林组合化合物中。