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1.发明申请Anti-aging Compositions Comprising Menyanthes Trifoliata Leaf Extracts and Methods of Use Thereof 审中-公开抗衰老组合物，包括五味子叶提取物及其使用方法公开(公告)号：US20080025930A1
公开(公告)日：2008-01-31
申请号：US11461093
申请日：2006-07-31
申请人： Hugo Corstjens , Lieve Declercq , Ilse Sente , Annelise Lobstein , Bernard Weniger , Robert Anton
发明人： Hugo Corstjens , Lieve Declercq , Ilse Sente , Annelise Lobstein , Bernard Weniger , Robert Anton
CPC分类号： A61K36/51 , A61K8/365 , A61K8/368 , A61K8/602 , A61K8/97 , A61Q17/04 , A61Q19/00 , A61Q19/08
摘要： An anti-aging composition comprising a skin-beneficial amount of actives identified in Menyanthes trifoliata leaf, wherein the actives are inhibitors of one or more of MMP-1, 2 and 9 and/or scavengers of peroxynitrite. Also disclosed are methods of using such a composition, which include treating the skin for signs of chronological or pre-mature aging.
摘要翻译： 一种抗衰老组合物，其包含在Menyanthes trifoliata叶中鉴定的皮肤有益量的活性物质，其中所述活性物质是MMP-1,2和9中的一种或多种的抑制剂和/或过氧亚硝酸盐的清除剂。 还公开了使用这样的组合物的方法，其包括治疗皮肤按时间顺序或成熟前衰老的迹象。
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2.发明申请Anti-Aging Compositions Comprising Menyanthes Trifoliata Leaf Extracts And Methods Of Use Thereof 审中-公开抗老化组合物，包括五味子叶提取物及其使用方法公开(公告)号：US20110033397A1
公开(公告)日：2011-02-10
申请号：US12911438
申请日：2010-10-25
申请人： Hugo Corstjens , Lieve Declercq , Ilse Sente , Annelise Lobstein , Bernard Weniger , Robert Anton
发明人： Hugo Corstjens , Lieve Declercq , Ilse Sente , Annelise Lobstein , Bernard Weniger , Robert Anton
CPC分类号： A61K36/51 , A61K8/365 , A61K8/368 , A61K8/602 , A61K8/97 , A61Q17/04 , A61Q19/00 , A61Q19/08
摘要： An anti-aging composition comprising a skin-beneficial amount of actives identified in Menyanthes trifoliata leaf, wherein the actives are inhibitors of one or more of MMP-1, 2 and 9 and/or scavengers of peroxynitrite. Also disclosed are methods of using such a composition, which include treating the skin for signs of chronological or pre-mature aging.
摘要翻译： 一种抗衰老组合物，其包含在Menyanthes trifoliata叶中鉴定的皮肤有益量的活性物质，其中所述活性物质是MMP-1,2和9中的一种或多种的抑制剂和/或过氧亚硝酸盐的清除剂。 还公开了使用这样的组合物的方法，其包括治疗皮肤按时间顺序或成熟前衰老的迹象。
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3.发明申请Anti-Aging Compositions Comprising Menyanthes Trifoliata Leaf Extracts and Methods Of Use Thereof 审中-公开抗老化组合物，包括五味子叶提取物及其使用方法公开(公告)号：US20110171146A1
公开(公告)日：2011-07-14
申请号：US13021115
申请日：2011-02-04
申请人： Hugo Corstjens , Lieve Declercq , Ilse Sente , Annelise Lobstein , Bernard Weniger , Robert Anton
发明人： Hugo Corstjens , Lieve Declercq , Ilse Sente , Annelise Lobstein , Bernard Weniger , Robert Anton
CPC分类号： A61K8/365 , A61K8/368 , A61K8/602 , A61K8/97 , A61K36/51 , A61Q17/04 , A61Q19/00 , A61Q19/08
摘要： An anti-aging composition comprising a skin-beneficial amount of actives identified in Menyanthes trifoliata leaf, wherein the actives are inhibitors of one or more of MMP-1, 2 and 9 and/or scavengers of peroxynitrite. Also disclosed are methods of using such a composition, which include treating the skin for signs of chronological or pre-mature aging.
摘要翻译： 一种抗衰老组合物，其包含在Menyanthes trifoliata叶中鉴定的皮肤有益量的活性物质，其中所述活性物质是MMP-1,2和9中的一种或多种的抑制剂和/或过氧亚硝酸盐的清除剂。 还公开了使用这样的组合物的方法，其包括治疗皮肤按时间顺序或成熟前衰老的迹象。
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公开(公告)号：US20080095866A1
公开(公告)日：2008-04-24
申请号：US11574252
申请日：2004-09-14
IPC分类号： A61K31/665 , A61K31/661 , A61K36/61 , A61K36/752 , A61K36/87 , A61P17/00
CPC分类号： A61K36/00 , A61K31/66 , A61K36/87 , A61K2300/00
摘要： The present invention provides topical compositions containing phosphorylated polyphenols in combination with a topically acceptable carrier. The compositions of the invention provide a means for delayed delivery of the polyphenol to keratinous tissues, such as skin, hair and nails, with enzymes of the keratinous tissue dephosphorylating the polyphenol, and returning it to its native active form. The compositions are particularly useful in the regulation of skin conditions.
摘要翻译： 本发明提供含有磷酸化多酚与局部可接受的载体组合的局部组合物。 本发明的组合物提供了将多酚延迟递送到角质组织如皮肤，毛发和指甲的手段，其中角质组织的酶使多酚脱磷化并将其返回到其天然活性形式。 组合物特别可用于调节皮肤状况。
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公开(公告)号：US08465973B2
公开(公告)日：2013-06-18
申请号：US12481156
申请日：2009-06-09
IPC分类号： C12N5/00
CPC分类号： A61K36/00 , A61K31/66 , A61K36/87 , A61K2300/00
摘要： The present invention provides topical compositions containing phosphorylated polyphenols in combination with a topically acceptable carrier. The compositions of the invention provide a means for delayed delivery of the polyphenol to keratinous tissues, such as skin, hair and nails, with enzymes of the keratinous tissue dephosphorylating the polyphenol, and returning it to its native active form. The compositions are particularly useful in the regulation of skin conditions. the phosphorylated stilbene is a phosphorylated resveratrol or a phosphorylated resveratrol derivative.
摘要翻译： 本发明提供含有磷酸化多酚与局部可接受的载体组合的局部组合物。 本发明的组合物提供了将多酚延迟递送到角质组织如皮肤，毛发和指甲的手段，其中角质组织的酶使多酚脱磷化并将其返回到其天然活性形式。 组合物特别可用于调节皮肤状况。 磷酸化的二苯乙烯是磷酸化的白藜芦醇或磷酸化的白藜芦醇衍生物。
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公开(公告)号：US20090247490A1
公开(公告)日：2009-10-01
申请号：US12481156
申请日：2009-06-09
CPC分类号： A61K36/00 , A61K31/66 , A61K36/87 , A61K2300/00
摘要： The present invention provides topical compositions containing phosphorylated polyphenols in combination with a topically acceptable carrier. The compositions of the invention provide a means for delayed delivery of the polyphenol to keratinous tissues, such as skin, hair and nails, with enzymes of the keratinous tissue dephosphorylating the polyphenol, and returning it to its native active form. The compositions are particularly useful in the regulation of skin conditions. the phosphorylated stilbene is a phosphorylated resveratrol or a phosphorylated resveratrol derivative.
摘要翻译： 本发明提供含有磷酸化多酚与局部可接受的载体组合的局部组合物。 本发明的组合物提供了将多酚延迟递送到角质组织如皮肤，毛发和指甲的手段，其中角质组织的酶使多酚脱磷化并将其返回到其天然活性形式。 组合物特别可用于调节皮肤状况。 磷酸化的二苯乙烯是磷酸化的白藜芦醇或磷酸化的白藜芦醇衍生物。
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