公开(公告)号：US20060030614A1

公开(公告)日：2006-02-09

申请号：US11217643

申请日：2005-08-31

申请人： Jean Hildesheim ,  Sergey Finogueev ,  Judith Aronhime ,  Ben-Zion Dolitzky ,  Shoshana Ben-Valid ,  Iian Kor

发明人： Jean Hildesheim ,  Sergey Finogueev ,  Judith Aronhime ,  Ben-Zion Dolitzky ,  Shoshana Ben-Valid ,  Iian Kor

IPC分类号： A61K31/403 ,  C07D209/82

CPC分类号： C07D209/88

摘要： This invention relates to an improved process of preparing carvedilol, as well as a new crystalline hydrate and solvate and forms of carvedilol, processes for the manufacture thereof, and pharmaceutical compositions thereof.

公开(公告)号：US07485663B2

公开(公告)日：2009-02-03

申请号：US11217643

申请日：2005-08-31

申请人： Jean Hildesheim ,  Sergey Finogueev ,  Judith Aronhime ,  Ben-Zion Dolitzky ,  Shoshana Ben-Valid ,  IIan Kor

发明人： Jean Hildesheim ,  Sergey Finogueev ,  Judith Aronhime ,  Ben-Zion Dolitzky ,  Shoshana Ben-Valid ,  IIan Kor

IPC分类号： A61K31/403 ,  C07C209/82

CPC分类号： C07D209/88

摘要： This invention relates to an improved process of preparing carvedilol, as well as a new crystalline hydrate and solvate and forms of carvedilol, processes for the manufacture thereof, and pharmaceutical compositions thereof.