Plug and gland aseptic package system
    1.
    发明授权
    Plug and gland aseptic package system 失效
    插头和无菌包装系统

    公开(公告)号:US06925780B1

    公开(公告)日:2005-08-09

    申请号:US09720604

    申请日:1999-06-25

    CPC分类号: B65B55/022 B65D47/121

    摘要: A method of aseptically filling an internally sterilized sealed container having a transfer port which comprises a tubular body which is sealed to the wall of the container and defines a flow passage therethrough, and a sealing plug engaged into the passage, the tubular body having an annular outer sealing face thereon which surrounds the flow passage, including the steps of: supporting the tubular body of the container in a selected orientation and position; providing a sterilization and filling head having at least an outer sealing ring thereon which is adapted to engage and seal with the annular sealing face, and a sterilization chamber located inwards of and at least partially defined by the outer sealing ring; bringing the sterilization and filling head and the tubular body into engagement with each other so that the outer sealing face; introducing a sterilization fluid into the sterilization chamber to sterilize at least the radially outer part of the plug and that part of the tubular body within the outer sealing ring; withdrawing the plug out of the tubular body in a direction away from the container whilst maintaining the sealing ring in sealed contact with the sealing face; introducing a flowable material into the container through the tubular body; reinserting the plug into the tubular body to thereby close the tubular body; and disengaging the sterilization and filling head and the tubular body from each other.

    摘要翻译: 一种无菌填充内部灭菌的密封容器的方法,该密封容器具有一个转运口,该转运口包括一个管状体,该管状体密封在容器的壁上并限定了一个通过其的流动通道,以及一个与该通道接合的密封塞, 围绕流动通道的外部密封面包括以下步骤:将容器的管状体以选定的取向和位置支撑; 提供灭菌和填充头,其具有至少一个适于与环形密封面接合和密封的外部密封环,以及位于外部密封环内部并至少部分地由外部密封环限定的消毒室; 使灭菌和填充头和管状体彼此接合,使得外密封面; 将灭菌流体引入灭菌室,以至少在塞子的径向外部部分和该外部密封环内的管状体的该部分消毒; 在将密封环与密封面密封接触的同时,将管塞从远离容器的方向排出管塞; 通过所述管状体将可流动材料引入所述容器; 将塞子重新插入管状体中,从而封闭管状体; 并且使灭菌和填充头与管状体相互脱离。