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公开(公告)号：US07479287B2
公开(公告)日：2009-01-20
申请号：US11496877
申请日：2006-07-31
申请人： Etienne Soudant , Lea Bezalel , Meira Ziv , Inon Perry
发明人： Etienne Soudant , Lea Bezalel , Meira Ziv , Inon Perry
CPC分类号： A61Q3/00 , A23B7/154 , A61K8/97 , A61K35/12 , A61K35/612 , A61K36/00 , A61K36/896 , A61Q19/00 , Y10S514/863 , A61K2300/00
摘要： A dormant preparation (DC) is provided which is capable of inhibiting proliferation of various kinds of cells. The preparation comprises an extract which is obtained from cells or tissue originating in an organism capable of entering a phase of dormancy in at least one of its parts and comprises at least one substance which induces or maintains the state of dormancy in the organism from which the cells or tissue are derived. The DC may be used for a variety of indications including human medicine and cosmetics, plant growth control and food preservation.
摘要翻译： 提供了能够抑制各种细胞增殖的休眠制剂（DC）。 该制剂包含从源自生物体的细胞或组织获得的提取物，所述细胞或组织能够在其至少一部分中进入休眠阶段，并且包含至少一种在生物体中诱导或维持休眠状态的物质， 导出细胞或组织。 DC可用于各种适应症，包括人类药物和化妆品，植物生长控制和食物保存。
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公开(公告)号：US06635287B2
公开(公告)日：2003-10-21
申请号：US09915768
申请日：2001-07-27
申请人： Etienne Soudant , Lea Bezalel , Meira Ziv , Inon Perry
发明人： Etienne Soudant , Lea Bezalel , Meira Ziv , Inon Perry
IPC分类号： A61K3578
CPC分类号： A61Q3/00 , A23B7/154 , A61K8/97 , A61K35/12 , A61K35/612 , A61K36/00 , A61K36/896 , A61Q19/00 , Y10S514/863 , A61K2300/00
摘要： A dormant preparation (DC) is provided which is capable of inhibiting proliferation of various kinds of cells. The preparation comprises an extract which is obtained from cells or tissue originating in an organism capable of entering a phase of dormancy in at least one of its parts and comprises at least one substance which induces or maintains the state of dormancy in the organism from which the cells or tissue are derived. The DC may be used for a variety of indications including human medicine and cosmetics, plant growth control and food preservation.
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公开(公告)号：US20210060108A1
公开(公告)日：2021-03-04
申请号：US16957814
申请日：2018-12-19
IPC分类号： A61K36/28
摘要： Extracts derived from plants and/or fractions thereof, compositions comprising same and methods and use thereof in protecting tissues from damage caused by toxins are encompassed herein. More particularly, compositions comprising a polar solvent extract and/or a fraction thereof derived from an Inula plant (e.g., Inula helenium) and methods and use thereof in protecting tissues comprising epithelial cells from adverse effects of toxins, particularly exogenous toxins originating from environmental pollution, are encompassed herein.
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公开(公告)号：US20110212040A1
公开(公告)日：2011-09-01
申请号：US13035976
申请日：2011-02-27
申请人： Lea VON OPPEN BEZALEL , Fabien HAVAS , Ilana KACHKO-CHERNETSKY , Alex ALILUIKO , Danit FISHBEIN MANOR , Olga BEN CHITRIT , Inon PERRY
发明人： Lea VON OPPEN BEZALEL , Fabien HAVAS , Ilana KACHKO-CHERNETSKY , Alex ALILUIKO , Danit FISHBEIN MANOR , Olga BEN CHITRIT , Inon PERRY
摘要： Sunscreen compositions comprising at least one sunscreen active wherein said sunscreen active and composition are stabilized by the addition natural or synthetic phytoene or phytofluene or mixtures thereof and optionally at least one other natural or synthetic carotenoid. A method of stabilization of sunscreen compositions and sunscreen actives, especially avobenzone, when exposed to UV light and free radicals attack.
摘要翻译： 包含至少一种防晒活性物质的防晒组合物，其中所述防晒活性物质和组合物通过加入天然或合成的八氢番茄红素或植物荧光素或其混合物和任选的至少一种其它天然或合成的类胡萝卜素来稳定。 当暴露于紫外光和自由基攻击时，防晒组合物和防晒活性物质，特别是阿伏苯宗的稳定化方法。
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公开(公告)号：US07482032B2
公开(公告)日：2009-01-27
申请号：US10097730
申请日：2002-03-14
申请人： Etienne Soudant , Lea Bezalel , Hedva Schickler , Judith Paltiel , Ami Ben-Amotz , Aviv Shaish , Inon Perry
发明人： Etienne Soudant , Lea Bezalel , Hedva Schickler , Judith Paltiel , Ami Ben-Amotz , Aviv Shaish , Inon Perry
CPC分类号： A61K31/01 , A23L33/105 , A23V2002/00 , A61K8/31 , A61K8/671 , A61K8/9706 , A61K31/015 , A61K2800/522 , A61Q17/00 , A61Q17/04 , A61Q19/00 , A61K2300/00 , A23V2250/211
摘要： A preparation comprising the carotenoids phytoene and phytofluene in an amount which, in combination, is effective in preventing various kinds of damage resulting from oxidation and exposure to UV light is provided. The preparation is essentially colorless and may be used as a topical cosmetic or pharmaceutical preparation as well as an additive in food preparations. In addition, a method for producing substantive amounts of phytoene and phytofluene from carotenoid producing organisms is described as well.
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公开(公告)号：US06342254B1
公开(公告)日：2002-01-29
申请号：US09367898
申请日：1999-11-29
申请人： Etienne Soudant , Lea Bezalel , Meira Ziv , Inon Perry
发明人： Etienne Soudant , Lea Bezalel , Meira Ziv , Inon Perry
IPC分类号： A61K3578
CPC分类号： A61Q3/00 , A23B7/154 , A61K8/97 , A61K35/12 , A61K35/612 , A61K36/00 , A61K36/896 , A61Q19/00 , Y10S514/863 , A61K2300/00
摘要： A dormant preparation (DC) is provided which is capable of inhibiting proliferation of various kinds of cells. The preparation comprises an extract which is obtained from cells or tissue originating in an organism capable of entering a phase of dormancy in at least one of its parts and comprises at least one substance which induces or maintains the state of dormancy in the organism from which the cells or tissue are derived. The DC may be used for a variety of indications including human medicine and cosmetics, plant growth control and food preservation. A preferred dormant preparation is prepared from a water extract of Narcissus (daffodil) bulb.
摘要翻译： 提供了能够抑制各种细胞增殖的休眠制剂（DC）。 该制剂包含从源自生物体的细胞或组织获得的提取物，所述细胞或组织能够在其至少一部分中进入休眠阶段，并且包含至少一种在生物体中诱导或维持休眠状态的物质， 导出细胞或组织。 DC可用于各种适应症，包括人类药物和化妆品，植物生长控制和食物保存。 优选的休眠制剂由水仙花（水仙花）灯泡的水提取物制备。
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公开(公告)号：US20090311204A1
公开(公告)日：2009-12-17
申请号：US12306888
申请日：2007-05-29
申请人： Liki Von Oppen Bezalel , Etienne Soudant , Inon Perry , Fumio Maniwa , Yuki Hata , Akemi Takayama
发明人： Liki Von Oppen Bezalel , Etienne Soudant , Inon Perry , Fumio Maniwa , Yuki Hata , Akemi Takayama
摘要： The present invention relates to use of carotenoid preparations for promoting skin whitening. Particularly, the present invention discloses that a combination of phytoene and phytofluene is effective in whitening skin. The present invention further relates to carotenoid compositions comprising a combination of phytofluene and phytofluene effective in whitening skin and at least one additional carotenoid, particularly carotenoids devoid of highly intense color.
摘要翻译： 本发明涉及类胡萝卜素制剂用于促进皮肤美白的用途。 特别地，本发明公开了番茄红素和植物荧光素的组合对于增白皮肤有效。 本发明进一步涉及类胡萝卜素组合物，其包含有效美白皮肤的植物荧光素和植物荧光素的组合，以及至少一种额外的类胡萝卜素，特别是没有高度强烈颜色的类胡萝卜素。
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公开(公告)号：US20060160702A1
公开(公告)日：2006-07-20
申请号：US11289156
申请日：2005-11-28
申请人： Etienne Soudant , Lea Oppen-Bezalel , Meira Ziv , Inon Perry
发明人： Etienne Soudant , Lea Oppen-Bezalel , Meira Ziv , Inon Perry
摘要： The invention relates to anti-proliferative agents derived from plants, wherein the agents are capable of inducing a plant organ into a state of dormancy or maintaining the organ in the state of dormancy. The invention further discloses compositions comprising the anti-proliferative agents and the use of said compositions to inhibit undesired or deleterious cell proliferation in plant or mammal tissue.
摘要翻译： 本发明涉及来自植物的抗增殖剂，其中所述试剂能够诱导植物器官进入休眠状态或维持器官处于休眠状态。 本发明还公开了包含抗增殖剂的组合物和所述组合物在植物或哺乳动物组织中抑制不需要的或有害的细胞增殖的用途。
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公开(公告)号：US08398958B2
公开(公告)日：2013-03-19
申请号：US12306888
申请日：2007-05-29
申请人： Liki Von Oppen Bezalel , Etienne Soudant , Inon Perry , Fumio Maniwa , Yuki Hata , Akemi Takayama
发明人： Liki Von Oppen Bezalel , Etienne Soudant , Inon Perry , Fumio Maniwa , Yuki Hata , Akemi Takayama
摘要： The present invention relates to use of carotenoid preparations for promoting skin whitening. Particularly, the present invention discloses that a combination of phytoene and phytofluene is effective in whitening skin. The present invention further relates to carotenoid compositions comprising a combination of phytofluene and phytofluene effective in whitening skin and at least one additional carotenoid, particularly carotenoids devoid of highly intense color.
摘要翻译： 本发明涉及类胡萝卜素制剂用于促进皮肤美白的用途。 特别地，本发明公开了番茄红素和植物荧光素的组合对于增白皮肤有效。 本发明进一步涉及类胡萝卜素组合物，其包含有效美白皮肤的植物荧光素和植物荧光素的组合，以及至少一种额外的类胡萝卜素，特别是没有高度强烈颜色的类胡萝卜素。
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公开(公告)号：US20110171332A1
公开(公告)日：2011-07-14
申请号：US13063009
申请日：2009-09-13
IPC分类号： A61K36/185 , A61P21/02 , A61K8/97 , A61Q19/08
摘要： The present invention relates to Leucojum extracts, particularly to aqueous extract of Leucojum bulbs effective in inhibiting contraction of muscle cells or tissues and as an anti-oxidant, composition comprising same and use thereof for inhibiting muscle contractions, particularly cutaneous muscles effective in treating and preventing wrinkles, fine lines and oxidative damages of the skin.
摘要翻译： 本发明涉及白菜提取物，特别是涉及有效抑制肌肉细胞或组织收缩的白念珠菌的水提取物，以及作为抗氧化剂，包含其的组合物及其用于抑制肌肉收缩的用途，特别是有效治疗和预防的肌肉 皱纹，细纹和皮肤氧化损伤。
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