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公开(公告)号:US08883852B2
公开(公告)日:2014-11-11
申请号:US13124924
申请日:2009-10-21
申请人: Michael Epperly , Joel Greenberger , Jianfei Jiang , Valerian Kagan , John Lazo , Peter McDonald
发明人: Michael Epperly , Joel Greenberger , Jianfei Jiang , Valerian Kagan , John Lazo , Peter McDonald
IPC分类号: A61K31/64 , A61K31/17 , A61K31/4965 , A61K31/47 , A61K31/40
CPC分类号: A61K31/64
摘要: Provided herein are methods, for reducing, preventing, mitigating and treating damage caused by radiation. The methods comprise delivering a compound, as described herein, to a patient in an amount and dosage regimen effective to prevent, mitigate or treat damage caused by radiation or to mitigate apoptosis. The compounds comprise glyburide or other sulfonylurea hypoglycemic compounds or potassium channel inhibitors.
摘要翻译: 本文提供了减少,预防,减轻和治疗由辐射引起的损害的方法。 所述方法包括以有效预防,减轻或治疗由辐射引起的损伤或减轻细胞凋亡的量和剂量方案向患者递送本文所述的化合物。 化合物包括格列本脲或其他磺酰脲降血糖化合物或钾通道抑制剂。
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公开(公告)号:US3196551A
公开(公告)日:1965-07-27
申请号:US27966363
申请日:1963-05-08
申请人: PROVOST JOSEPH R , GIFFORD EDMUND C , JOHN LAZO
发明人: PROVOST JOSEPH R , GIFFORD EDMUND C , JOHN LAZO
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公开(公告)号:US20110288178A1
公开(公告)日:2011-11-24
申请号:US13124924
申请日:2009-10-21
申请人: Michael Epperly , Joel Greenberger , Jianfei Jiang , Valerian Kagan , John Lazo , Peter McDonald
发明人: Michael Epperly , Joel Greenberger , Jianfei Jiang , Valerian Kagan , John Lazo , Peter McDonald
CPC分类号: A61K31/64
摘要: Provided herein are methods, for reducing, preventing, mitigating and treating damage caused by radiation. The methods comprise delivering a compound, as described herein, to a patient in an amount and dosage regimen effective to prevent, mitigate or treat damage caused by radiation or to mitigate apoptosis. The compounds comprise glyburide or other sulfonylurea hypoglycemic compounds or potassium channel inhibitors.
摘要翻译: 本文提供了减少,预防,减轻和治疗由辐射引起的损害的方法。 所述方法包括以有效预防,减轻或治疗由辐射引起的损伤或减轻细胞凋亡的量和剂量方案向患者递送本文所述的化合物。 化合物包括格列本脲或其他磺酰脲降血糖化合物或钾通道抑制剂。
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公开(公告)号:US2761056A
公开(公告)日:1956-08-28
申请号:US33689753
申请日:1953-02-13
申请人: JOHN LAZO
发明人: JOHN LAZO
CPC分类号: G02B6/0018 , G01D11/28 , G02B6/0046 , Y10S116/36
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