公开(公告)号：US4906741A

公开(公告)日：1990-03-06

申请号：US280087

申请日：1988-12-05

申请人： James R. Hazen ,  William R. Lee

发明人： James R. Hazen ,  William R. Lee

IPC分类号： C09B27/00

摘要： The invention is directed toward compounds having the formula: ##STR1## wherein A is a substituent independently selected from the group consisting of lower alkyl having from 1 to 3 carbon atoms, chloro or fluoro; n is an integer independently selected from 0 to 2; and X is a halogen selected from the group consisting of chloro and fluoro.Compounds of this invention are useful as intermediates in the preparation of the corresponding diamine compounds resulting from the reductive cleavage of the azo linkage. They may also be used to prepare dyestuffs and photosensitive materials.

摘要翻译： 本发明涉及具有下式的化合物：其中A是独立地选自具有1至3个碳原子的低级烷基，氯或氟的取代基; n是独立地选自0至2的整数; X是选自氯和氟的卤素。 本发明的化合物可用作制备由偶氮键的还原性裂解产生的相应的二胺化合物的中间体。 它们也可用于制备染料和感光材料。

公开(公告)号：US4033986A

公开(公告)日：1977-07-05

申请号：US657304

申请日：1976-02-11

申请人： Richard L. Castenson ,  James R. Hazen ,  Rex Y. Tien

发明人： Richard L. Castenson ,  James R. Hazen ,  Rex Y. Tien

IPC分类号： C07C51/363 ,  C07C63/72 ,  C07D311/02

CPC分类号： C07C63/72 ,  C07C51/363

摘要： A novel method for the preparation of 4-bromo-1,8-naphthalic acid anhydride is disclosed. This method is carried out by the bromination, with alkali metal bromide or molecular bromine in the presence of a hypohalite, of a di-alkali metal salt of 1,8-naphthalic acid in aqueous solution at a pH of between 6.5 and 9.5 and at a temperature of between 0.degree. and 30.degree. C. to a di-alkali metal salt of 4-bromo-1,8-naphthalic acid and cyclizing to produce 4-bromo-1,8-naphthalic acid anhydride. This novel direct bromination method produces the desired product in good yields and high purity. 4-Bromo-1,8-naphthalic acid anhydride is a valuable intermediate for the preparation of dyestuffs, pigments and optical brighteners.

摘要翻译： 公开了制备4-溴-1,8-萘二甲酸酐的新方法。 该方法通过溴化，碱金属溴化物或分子溴在次卤酸盐存在下，在pH 6.5至9.5之间的水溶液中的1,8-萘二甲酸二碱金属盐和 温度在0℃至30℃之间，与4-溴-1,8-萘二甲酸的二碱金属盐反应，并环化生成4-溴-1,8-萘二甲酸酐。 这种新的直接溴化方法以良好的产率和高纯度产生所需的产物。 4-溴-1,8-萘二甲酸酐是制备染料，颜料和荧光增白剂的有价值的中间体。

公开(公告)号：US4749523A

公开(公告)日：1988-06-07

申请号：US725068

申请日：1985-04-24

申请人： James R. Hazen

发明人： James R. Hazen

IPC分类号： C07C309/15 ,  C07C67/00 ,  C07C301/00 ,  C07C303/22 ,  C07C303/32 ,  C07C309/51 ,  C07C143/53

CPC分类号： C07C309/15

摘要： This invention is directed to the acylation of aminosulfonic acids in the solid phase. Two discrete, sequential chemical reactions occur, i.e. (1) the neutralization of the aminosulfonic acid, and (2) the subsequent amine acylation, to produce an improved neutralized acyl-aminosulfonic acid at a reduced cost. Aminosulfonic acids having the general formula HO.sub.3 S-A-NH.sub.2 are acylated to neutralized acyl-aminosulfonic acids having the general formula RCONH-A-SO.sub.3 M, where A is an unsubstituted or substituted aliphatic, aromatic or heteroaromatic group and M is a neutralizing agent moiety. The yield is virtually quantitative.

摘要翻译： 本发明涉及固相中氨基磺酸的酰化。 发生两个不连续的连续化学反应，即（1）氨基磺酸的中和，和（2）随后的胺酰化，以降低的成本产生改进的中和的酰基 - 氨基磺酸。 将具有通式HO 3 S-A-NH 2的氨基磺酸酰化以中和具有通式RCONH-A-SO3M的酰基氨基磺酸，其中A是未取代或取代的脂族，芳族或杂芳族基团，M是中和剂部分。 产量实际上是定量的。

公开(公告)号：US5011997A

公开(公告)日：1991-04-30

申请号：US105857

申请日：1987-10-07

申请人： James R. Hazen ,  William R. Lee

发明人： James R. Hazen ,  William R. Lee

IPC分类号： C07C211/52 ,  B01J23/40 ,  C07B61/00 ,  C07C67/00 ,  C07C209/00 ,  C07C209/42 ,  C07C209/50 ,  C07C209/56 ,  C07C209/58 ,  C07C211/50 ,  C07C211/58

CPC分类号： C07C209/56 ,  C07C209/58

摘要： This invention is an improved process for preparing 2,2-bis(4-aminophenyl)hexafluoropropane which comprises subjecting 2,2-bis(4-aminocarbonylphenyl)hexafluoropropane to the Hofmann reaction and then treating that reaction product under reducing conditions to produce the desired amine in high yield.

公开(公告)号：US4769182A

公开(公告)日：1988-09-06

申请号：US741060

申请日：1985-06-05

申请人： James R. Hazen

发明人： James R. Hazen

IPC分类号： C07F9/30

CPC分类号： C07F9/304 ,  C07F9/301

摘要： 3-(Hydroxyphenylphosphinyl)-propanoic acid is produced by reacting phenylphosphonous dichloride with a 0 to 20 percent molar excess of acrylic acid at a temperature of 60.degree. to 150.degree. C., heating the reaction mixture at a temperature of 115.degree. to 150.degree. for at least 45 minutes, and then hydrolyzing the mixture to obtain the desired product.

摘要翻译： 3-（羟基苯基氧膦基） - 丙酸是通过使苯基二氯化膦与0至20摩尔过量的丙烯酸在60至150℃的温度下反应制得的，在115℃至150℃的温度下加热该反应混合物 至少45分钟，然后水解该混合物以获得所需的产物。