公开(公告)号：US5648208A

公开(公告)日：1997-07-15

申请号：US433805

申请日：1995-05-03

申请人： Jean Fourcart ,  Chantal Buffevant ,  Alain Huc

发明人： Jean Fourcart ,  Chantal Buffevant ,  Alain Huc

IPC分类号： G01N33/543 ,  G01N33/544 ,  C12Q1/70

CPC分类号： G01N33/544 ,  G01N33/54326 ,  Y10S436/814

摘要： The invention relates to the use of collagen as solid binding substrate for a sensor called ligand or refining agent, capable of reacting specifically with an element to be detected in a biological medium, to form a specific complex.Preferably, the solid substrate comprises atelocollagen or a mixture of atelocollagen and of polyholoside.The invention thus makes it possible to provide a biological reactant of high specificity and of which the constituents are of natural origin. It can be used easily and quickly.

摘要翻译： 本发明涉及胶原作为称为配体或精制剂的传感器的固体结合底物的用途，其能够与生物培养基中要检测的元件特异性反应以形成特定的复合物。 优选地，固体基质包含胶原蛋白或者胶原和多聚壳苷的混合物。 因此，本发明使得可以提供高特异性的生物反应物，并且其成分是天然来源的。 它可以方便快捷地使用。

公开(公告)号：US5567806A

公开(公告)日：1996-10-22

申请号：US469790

申请日：1995-06-06

申请人： Nabil Abdul-Malak ,  Jean Fourcart ,  Alain Huc

发明人： Nabil Abdul-Malak ,  Jean Fourcart ,  Alain Huc

IPC分类号： A61L27/00 ,  A61F2/00 ,  A61L27/24 ,  A61L31/00 ,  A61L31/04 ,  A61K35/32 ,  A61K38/39 ,  A61L15/20 ,  C07K14/78

CPC分类号： A61L31/044 ,  A61L27/24 ,  A61F2310/00365 ,  Y10S128/08 ,  Y10S530/84 ,  Y10S530/842 ,  Y10S602/90

摘要： Suturable, biocompatible, control-resorbing membranes are disclosed for use in guided tissue regeneration, comprising a cross-linked collagen material either obtained by crosslinking a starting collagen material in the coagulated state produced by coagulation of a collagen material gel with a coagulating agent or obtained by crosslinking of a sponge of a collagen material on which a collagen material gel has been poured before performing the crosslinking.

摘要翻译： 公开了用于引导组织再生的可固化，生物相容的控制吸收膜，其包括交联的胶原材料，其通过将由胶原材料凝胶凝结产生的凝固状态的起始胶原材料与凝固剂交联或获得 通过在进行交联之前交联其上已经注入了胶原材料凝胶的胶原材料的海绵。