Methods and systems for evaluating health risk factors by measurement of DNA damage and DNA repair
    1.
    发明申请
    Methods and systems for evaluating health risk factors by measurement of DNA damage and DNA repair 审中-公开
    通过测量DNA损伤和DNA修复来评估健康危险因素的方法和系统

    公开(公告)号:US20070269824A1

    公开(公告)日:2007-11-22

    申请号:US11713451

    申请日:2007-03-02

    IPC分类号: C12Q1/68

    摘要: Disclosed are methods for measuring the effects of environmental, physiological, or lifestyle variables on DNA damage and DNA repair activity as well as the use of measurements of DNA damage and DNA repair activity to predict increased risk for disease. Embodiments of the methods involve the use of a combination of assays to measure DNA damage and DNA repair activity in an individual and comparing these measurements to suitable controls using the selected assays for normal healthy individuals of varying ages. In other embodiments, the methods may comprise a comparison of DNA damage levels to DNA repair levels to obtain an apparent net measurement of DNA damage accumulation.

    摘要翻译: 公开了测量环境,生理或生活方式变量对DNA损伤和DNA修复活性的影响的方法,以及使用DNA损伤和DNA修复活动的测量来预测增加的疾病风险。 方法的实施方案涉及使用测定的组合来测量个体中的DNA损伤和DNA修复活性,并且使用针对不同年龄的正常健康个体的所选测定将这些测量与合适的对照进行比较。 在其他实施方案中,所述方法可以包括DNA损伤水平与DNA修复水平的比较,以获得DNA损伤积累的明显净测量。

    TOWED VEHICLE STABILIZING APPARATUS
    2.
    发明申请
    TOWED VEHICLE STABILIZING APPARATUS 审中-公开
    强制车辆稳定装置

    公开(公告)号:US20090200782A1

    公开(公告)日:2009-08-13

    申请号:US12027415

    申请日:2008-02-07

    IPC分类号: B60S9/04

    CPC分类号: B60S9/04

    摘要: An apparatus for stabilizing a towed vehicle when stationary, such as a fifth wheel trailer. A pair of independent stabilizing legs is attached to the pin box for towed vehicle, each of the leg being attached to an opposite side of the pin box by means of a universal joint. When deployed, a fine adjustment extends between the legs for altering the leg spacing. When stowed, each of the leg is located in a bracket shaped to engage and retain the leg.

    摘要翻译: 一种用于在静止时稳定拖车的装置,例如第五轮拖车。 一对独立的稳定腿连接到用于拖车的销盒,每个腿通过万向接头附接到销盒的相对侧。 当部署时,在腿之间进行微调,以改变腿间距。 当收起时,每个腿都位于托架和托架中。

    MEDICAL MANAGEMENT SYSTEM
    3.
    发明申请
    MEDICAL MANAGEMENT SYSTEM 审中-公开
    医疗管理系统

    公开(公告)号:US20080046295A1

    公开(公告)日:2008-02-21

    申请号:US11857684

    申请日:2007-09-19

    申请人: JEFFREY ALBRECHT

    发明人: JEFFREY ALBRECHT

    IPC分类号: G06Q50/00 G06F17/30 G06F17/40

    摘要: A medical management system. The burdensome task of medication logging is greatly reduced for a patient when compared to conventional methods to perform these tasks. Moreover, the invention allows for pharmaceutical supplier/providers and healthcare providers the ability better to manage, track, and trend the medication and products that must be provided to patients. This integrated ability allows for better management of the inventory of highly perishable and life-saving medications for chronically ill patients. The invention also allows for highly accurate communication between patients and other parties including his/her medical doctor, a pharmaceutical supplier/provider who provides medications and products for the patient, as well as the insurance provider providing medical insurance coverage for the patient. The system integrates embedded functionality that ensures that in the accidental event that a patient is prescribed tainted medication, the patient is warned of the taint in due time before self-administering the medication to avoid potentially contracting a disease or other ailment from the tainted medication. Patient medication is tracked and trending over the lifetime of the medication and the treatment period for the patient. Exceptions that outlay the trending of the patient's medication are identified and properly communicated, sometimes automatically, to a healthcare provider or medical doctor who treats the patient. The system is adaptable for use generally or to treat specific diseases, such as chronic diseases as hemophilia, diabetes, asthma, HIV, and other diseases requiring long term treatment and ongoing administration of medications and products.

    摘要翻译: 医疗管理系统 与执行这些任务的常规方法相比,患者的用药记录的繁重任务大大减少。 此外,本发明允许药物供应商/提供者和医疗保健提供者更好地管理,跟踪和趋势必须提供给患者的药物和产品。 这种综合能力可以更好地管理长期患病患者高度易腐和挽救生命的药物。 本发明还允许患者和其他方之间的高度准确的通信,包括他/她的医生,为患者提供药物和产品的药物供应商/供应商以及为患者提供医疗保险的保险提供者。 该系统集成了嵌入式功能,确保在患者被规定的感染药物的意外事件中,病人在适当的时候被警告,在自行管理药物之前,以避免潜在地将疾病或其他疾病从受污染的药物中收缩。 病人的药物在药物的使用期限和患者的治疗期间被跟踪和趋向。 识别病人药物趋势的例外情况,并有时自动通知给治疗患者的医护人员或医生。 该系统适用于一般使用或治疗特定疾病,如慢性疾病如血友病,糖尿病,哮喘,艾滋病毒等需要长期治疗和持续管理药物和产品的其他疾病。

    Wedge-type breechblock bidirectional make-break assembly
    4.
    发明授权
    Wedge-type breechblock bidirectional make-break assembly 有权
    楔形臀部双向断裂装配

    公开(公告)号:US08371206B1

    公开(公告)日:2013-02-12

    申请号:US12749700

    申请日:2010-03-30

    IPC分类号: F41A19/00

    摘要: A gun with a wedge-type breechblock containing a single make-break junction assembly, located between the stationary mass of the cradle and the breechblock. The make-break junction assembly having a first set of contacts located along the bottom of the ramp structure affixed to the cradle and a second set of contacts housed in a shoe affixed to the bottom of the breechblock, at a location corresponding to the first set of contacts. Such that, when the breechblock is in-battery and the gun loaded, this shoe will be aligned with and adjacent to the first set of contacts, so that the make-break circuit will be completed.

    摘要翻译: 具有楔形膛形枪的枪,其包含位于支架的静止质量块和后膛块之间的单个断裂连接部件。 所述断裂连接组件具有沿着固定到所述托架的所述斜坡结构的底部定位的第一组触点,以及容纳在固定到所述后膛的底部的鞋中的第二组触点,在对应于所述第一组的位置 的联系人。 这样,当膛体处于电池状态并且枪装载时,该鞋将与第一组触点对准并相邻,使得断线回路完成。