摘要:
Disclosed are methods for measuring the effects of environmental, physiological, or lifestyle variables on DNA damage and DNA repair activity as well as the use of measurements of DNA damage and DNA repair activity to predict increased risk for disease. Embodiments of the methods involve the use of a combination of assays to measure DNA damage and DNA repair activity in an individual and comparing these measurements to suitable controls using the selected assays for normal healthy individuals of varying ages. In other embodiments, the methods may comprise a comparison of DNA damage levels to DNA repair levels to obtain an apparent net measurement of DNA damage accumulation.
摘要:
An apparatus for stabilizing a towed vehicle when stationary, such as a fifth wheel trailer. A pair of independent stabilizing legs is attached to the pin box for towed vehicle, each of the leg being attached to an opposite side of the pin box by means of a universal joint. When deployed, a fine adjustment extends between the legs for altering the leg spacing. When stowed, each of the leg is located in a bracket shaped to engage and retain the leg.
摘要:
A medical management system. The burdensome task of medication logging is greatly reduced for a patient when compared to conventional methods to perform these tasks. Moreover, the invention allows for pharmaceutical supplier/providers and healthcare providers the ability better to manage, track, and trend the medication and products that must be provided to patients. This integrated ability allows for better management of the inventory of highly perishable and life-saving medications for chronically ill patients. The invention also allows for highly accurate communication between patients and other parties including his/her medical doctor, a pharmaceutical supplier/provider who provides medications and products for the patient, as well as the insurance provider providing medical insurance coverage for the patient. The system integrates embedded functionality that ensures that in the accidental event that a patient is prescribed tainted medication, the patient is warned of the taint in due time before self-administering the medication to avoid potentially contracting a disease or other ailment from the tainted medication. Patient medication is tracked and trending over the lifetime of the medication and the treatment period for the patient. Exceptions that outlay the trending of the patient's medication are identified and properly communicated, sometimes automatically, to a healthcare provider or medical doctor who treats the patient. The system is adaptable for use generally or to treat specific diseases, such as chronic diseases as hemophilia, diabetes, asthma, HIV, and other diseases requiring long term treatment and ongoing administration of medications and products.
摘要:
A gun with a wedge-type breechblock containing a single make-break junction assembly, located between the stationary mass of the cradle and the breechblock. The make-break junction assembly having a first set of contacts located along the bottom of the ramp structure affixed to the cradle and a second set of contacts housed in a shoe affixed to the bottom of the breechblock, at a location corresponding to the first set of contacts. Such that, when the breechblock is in-battery and the gun loaded, this shoe will be aligned with and adjacent to the first set of contacts, so that the make-break circuit will be completed.